Success Metrics

Clinical Success Rate
66.7%

Based on 6 completed trials

Completion Rate
67%(6/9)
Active Trials
16(50%)
Results Posted
150%(9 trials)
Terminated
3(9%)

Phase Distribution

Ph phase_2
9
28%
Ph phase_3
2
6%
Ph not_applicable
12
38%
Ph phase_1
6
19%

Phase Distribution

6

Early Stage

9

Mid Stage

2

Late Stage

Phase Distribution29 total trials
Phase 1Safety & dosage
6(20.7%)
Phase 2Efficacy & side effects
9(31.0%)
Phase 3Large-scale testing
2(6.9%)
N/ANon-phased studies
12(41.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

6 of 12 finished

Non-Completion Rate

50.0%

6 ended early

Currently Active

16

trials recruiting

Total Trials

32

all time

Status Distribution
Active(16)
Completed(6)
Terminated(6)
Other(4)

Detailed Status

Recruiting9
Active, not recruiting7
Completed6
unknown4
Terminated3
Withdrawn3

Development Timeline

Analytics

Development Status

Total Trials
32
Active
16
Success Rate
66.7%
Most Advanced
Phase 3

Trials by Phase

Phase 16 (20.7%)
Phase 29 (31.0%)
Phase 32 (6.9%)
N/A12 (41.4%)

Trials by Status

completed619%
terminated39%
unknown413%
active_not_recruiting722%
recruiting928%
withdrawn39%

Recent Activity

Clinical Trials (32)

Showing 20 of 32 trialsScroll for more
NCT01419067Phase 2

A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection

Active Not Recruiting
NCT02792582Phase 2

A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection

Active Not Recruiting
NCT07213934Phase 1

Phase I/ II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma

Recruiting
NCT03323463Phase 2

Major De-escalation to 30 Gy for Select Human Papillomavirus Associated Oropharyngeal Carcinoma

Active Not Recruiting
NCT07450560

Research on Real-time Proton Therapy Guidance Through Monitoring Proton Range Using All-digital PET

Active Not Recruiting
NCT07412314Not Applicable

Proton Therapy for Recurrent Nasopharyngeal Carcinoma

Recruiting
NCT04908709Not Applicable

Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors

Recruiting
NCT02125786Phase 2

A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma

Active Not Recruiting
NCT01449149Not Applicable

Proton Radiation for Chordomas and Chondrosarcomas

Completed
NCT05856773Phase 3

Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy

Recruiting
NCT01352429

Mild Hypofractionation With Proton Therapy or IMRT for Intermediate-Risk Prostate Cancer

Active Not Recruiting
NCT06883604Not Applicable

Clinical Investigation of Proton Treatment in Hodgkin Lymphoma Patients - PRO-Hodgkin

Recruiting
NCT05350475Not Applicable

Protons Vs. Photons for High-risk Prostate Cancer

Recruiting
NCT01839838Phase 1

APBI Proton Feasibility and Phase II Study

Completed
NCT06180434

Short Term Outcomes After PRoton and PhotoN RadiOtherapy for IDH Mutated Grade 2 and 3 Gliomas

Recruiting
NCT03018418Phase 2

Proton Therapy in Reducing Toxicity in Anal Cancer

Active Not Recruiting
NCT06462378Phase 2

Proton Therapy for Locally Advanced Cervical Cancer

Recruiting
NCT03267836Phase 1

Neoadjuvant Avelumab and Hypofractionated Proton Radiation Therapy Followed by Surgery for Recurrent Radiation-refractory Meningioma

Terminated
NCT05203120Not Applicable

A National Phase II Study of Proton Therapy in Hepatocellular Carcinoma

Recruiting
NCT01795300Not Applicable

Comparison of Proton and Carbon Ion Radiotherapy With Advanced Photon Radiotherapy in Skull Base Meningiomas: The PINOCCHIO Trial.

Withdrawn

Drug Details

Intervention Type
DEVICE
Total Trials
32