Success Metrics

Clinical Success Rate
60.0%

Based on 6 completed trials

Completion Rate
60%(6/10)
Active Trials
9(35%)
Results Posted
33%(2 trials)
Terminated
4(15%)

Phase Distribution

Ph phase_2
11
42%
Ph phase_3
2
8%
Ph early_phase_1
4
15%
Ph not_applicable
3
12%
Ph phase_1
5
19%
Ph phase_4
1
4%

Phase Distribution

9

Early Stage

11

Mid Stage

3

Late Stage

Phase Distribution26 total trials
Early Phase 1First-in-human
4(15.4%)
Phase 1Safety & dosage
5(19.2%)
Phase 2Efficacy & side effects
11(42.3%)
Phase 3Large-scale testing
2(7.7%)
Phase 4Post-market surveillance
1(3.8%)
N/ANon-phased studies
3(11.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

54.5%

6 of 11 finished

Non-Completion Rate

45.5%

5 ended early

Currently Active

9

trials recruiting

Total Trials

26

all time

Status Distribution
Active(9)
Completed(6)
Terminated(5)
Other(6)

Detailed Status

Recruiting8
Completed6
Terminated4
unknown4
Suspended2
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
26
Active
9
Success Rate
60.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (15.4%)
Phase 15 (19.2%)
Phase 211 (42.3%)
Phase 32 (7.7%)
Phase 41 (3.8%)
N/A3 (11.5%)

Trials by Status

active_not_recruiting14%
recruiting831%
suspended28%
terminated415%
completed623%
unknown415%
withdrawn14%

Recent Activity

Clinical Trials (26)

Showing 20 of 26 trialsScroll for more
NCT04848519Phase 2

Immune Checkpoint Inhibitors With or Without Propranolol Hydrochloride In Patients With Urothelial Carcinoma

Active Not Recruiting
NCT05997732Phase 4

Sympathetic Neurovascular Transduction: Role of Adrenergic Receptors and Sex Differences

Recruiting
NCT05651594Phase 2

Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma

Recruiting
NCT04713657Phase 1

Beta-blocker Administration for Cardiomyocyte Division

Recruiting
NCT06833320Phase 1

Propranolol Treatment for Postoperative Chylothorax

Recruiting
NCT05085782Phase 2

Reconsolidation Therapy With Propranolol as a Treatment for Chronic Pain

Completed
NCT06787066Early Phase 1

Sympathetic Vascular Transduction Across the Menopause Transition: Contributing Mechanisms

Recruiting
NCT06445166Phase 2

Propranolol for the Treatment of Kaposi Sarcoma in Adults

Recruiting
NCT05419193Phase 2

PROpranolol for Cerebral Hemorrhage-ASsociated pnEumonia (PRO-CHASE)

Completed
NCT03384836Phase 1

Propranolol Hydrochloride and Pembrolizumab in Treating Patients With Stage IIIC-IV Melanoma That Cannot Be Removed by Surgery

Suspended
NCT05219799Early Phase 1

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Recruiting
NCT03633747Phase 1

Efficacy Evaluation of Propranolol Treatment of Hepatic Hemangioma

Terminated
NCT03152786Phase 2

Propranolol Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery

Terminated
NCT05979818Phase 1

Propranolol Hydrochloride in Combination With Sintilimab and Platinum-based Chemotherapy for Treatment of Advanced Non-small Cell Lung Cancer

Recruiting
NCT05525416Not Applicable

Sex Differences in Sympathetic Vascular Reactivity at High Altitude

Completed
NCT04299438Phase 3

Propranolol Rescue of Prolonged Labor

Terminated
NCT02013492Early Phase 1

Propranolol Hydrochloride in Treating Patients With Locally Recurrent or Metastatic Solid Tumors That Cannot Be Removed By Surgery

Completed
NCT04467086Phase 3

Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical Ventilation

Completed
NCT01555554Not Applicable

Perioperative Propranolol in Patients With Post Traumatic Stress Disorder (PTSD)

Terminated
NCT03152175Phase 2

Posttraumatic Stress Disorders in Police, Correctional Service Officers, and 911 Operators

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
26