Success Metrics

Clinical Success Rate
90.9%

Based on 20 completed trials

Completion Rate
91%(20/22)
Active Trials
0(0%)
Results Posted
45%(9 trials)
Terminated
2(9%)

Phase Distribution

Ph phase_1
13
59%
Ph phase_2
8
36%
Ph phase_3
1
5%

Phase Distribution

13

Early Stage

8

Mid Stage

1

Late Stage

Phase Distribution22 total trials
Phase 1Safety & dosage
13(59.1%)
Phase 2Efficacy & side effects
8(36.4%)
Phase 3Large-scale testing
1(4.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

90.9%

20 of 22 finished

Non-Completion Rate

9.1%

2 ended early

Currently Active

0

trials recruiting

Total Trials

22

all time

Status Distribution
Completed(20)
Terminated(2)

Detailed Status

Completed20
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
22
Active
0
Success Rate
90.9%
Most Advanced
Phase 3

Trials by Phase

Phase 113 (59.1%)
Phase 28 (36.4%)
Phase 31 (4.5%)

Trials by Status

completed2091%
terminated29%

Recent Activity

Clinical Trials (22)

Showing 20 of 22 trialsScroll for more
NCT04006457Phase 3

Long-Term PF-06651600 for the Treatment of Alopecia Areata

Completed
NCT04517864Phase 2

PLACEBO-CONTROLLED SAFETY STUDY OF RITLECITINIB (PF-06651600) IN ADULTS WITH ALOPECIA AREATA

Terminated
NCT05549934Phase 2

Ritlecitinib for Cicatricial Alopecia

Completed
NCT03395184Phase 2

Study To Evaluate The Efficacy And Safety Of Oral PF-06651600 And PF-06700841 In Subjects With Moderate To Severe Crohn's Disease

Completed
NCT04413617Phase 2

TO ASSESS THE EFFICACY AND SAFETY OF PF-06650833, PF-06651600, AND TOFACITINIB ALONE AND IN COMBINATION IN PARTICIPANTS WITH ACTIVE RHEUMATOID ARTHRITIS WITH AN INADEQUATE RESPONSE TO METHOTREXATE

Completed
NCT02958865Phase 2

Study to Compare Oral PF-06651600, PF-06700841 and Placebo in Subjects With Moderate to Severe Ulcerative Colitis

Completed
NCT03715829Phase 2

A Phase 2b Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Active Non-segmental Vitiligo Subjects

Completed
NCT04390776Phase 1

Bioequivalence Study of PF-06651600 Capsules Relative to Tablets and Estimation of Food Effect on Capsules.

Completed
NCT04037865Phase 1

A Renal Impairment Study for PF-06651600

Terminated
NCT04634565Phase 1

PHARMACOKINETIC CHARACTERIZATION OF PF-06651600 IN CHINESE ADULT PARTICIPANTS

Completed
NCT04266509Phase 1

Study to Evaluate the Effect of Repeat-Dose Rifampin on the Pharmacokinetics (PK) of PF-06651600

Completed
NCT04355845Phase 1

A STUDY TO EVALUATE THE EFFECT OF PF-06651600 ON PHARMACOKINETICS OF SINGLE DOSE SUMATRIPTAN IN HEALTHY PARTICIPANTS.

Completed
NCT02974868Phase 2

Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Subjects With Alopecia Areata

Completed
NCT04092595Phase 1

A Study of PF-06651600 Effect on Rosuvastatin Pharmacokinetics in Healthy Participants

Completed
NCT04018274Phase 1

Effect of PF-06651600 on the Pharmacokinetics of Oral Contraceptive Steroids

Completed
NCT04004663Phase 1

Bioavailability Study of PF-06651600 Formulations in Healthy Participants

Completed
NCT03929510Phase 1

Study to Characterize Absorption, Distribution, Metabolism and Excretion of 14C PF-06651600 and to Evaluate the Absolute Oral Bioavailability and Fraction Absorbed of PF-06651600.

Completed
NCT03608241Phase 1

A STUDY TO ESTIMATE THE EFFECT OF PF-06651600 ON THE PHARMACOKINETICS (PK) OF ORAL CONTRACEPTIVE (OC)

Completed
NCT03762928Phase 1

ESTIMATION OF THE EFFECT OF MULTIPLE DOSE PF-06651600 ON THE PHARMACOKINETICS OF SINGLE DOSE MIDAZOLAM AND EFAVIRENZ

Completed
NCT02969044Phase 2

Study To Assess The Efficacy And Safety Of Pf-06651600 In Subjects With Rheumatoid Arthritis With An Inadequate Response To Methotrexate

Completed

Drug Details

Intervention Type
DRUG
Total Trials
22