Success Metrics

Clinical Success Rate
88.4%

Based on 336 completed trials

Completion Rate
88%(336/380)
Active Trials
18(4%)
Results Posted
35%(116 trials)
Terminated
44(9%)

Phase Distribution

Ph early_phase_1
2
0%
Ph not_applicable
24
5%
Ph phase_3
64
13%
Ph phase_2
236
49%
Ph phase_4
1
0%
Ph phase_1
149
31%

Phase Distribution

151

Early Stage

236

Mid Stage

65

Late Stage

Phase Distribution476 total trials
Early Phase 1First-in-human
2(0.4%)
Phase 1Safety & dosage
149(31.3%)
Phase 2Efficacy & side effects
236(49.6%)
Phase 3Large-scale testing
64(13.4%)
Phase 4Post-market surveillance
1(0.2%)
N/ANon-phased studies
24(5.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

82.6%

336 of 407 finished

Non-Completion Rate

17.4%

71 ended early

Currently Active

18

trials recruiting

Total Trials

478

all time

Status Distribution
Active(18)
Completed(336)
Terminated(71)
Other(53)

Detailed Status

Completed336
unknown52
Terminated44
Withdrawn27
Active, not recruiting11
Recruiting7

Development Timeline

Analytics

Development Status

Total Trials
478
Active
18
Success Rate
88.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (0.4%)
Phase 1149 (31.3%)
Phase 2236 (49.6%)
Phase 364 (13.4%)
Phase 41 (0.2%)
N/A24 (5.0%)

Trials by Status

terminated449%
unknown5211%
withdrawn276%
suspended10%
recruiting71%
active_not_recruiting112%
completed33670%

Recent Activity

Clinical Trials (478)

Showing 20 of 478 trialsScroll for more
NCT01318317Phase 1

Genetically Engineered Lymphocyte Therapy After Peripheral Blood Stem Cell Transplant in Treating Patients With High-Risk, Intermediate-Grade, B-cell Non-Hodgkin Lymphoma

Active Not Recruiting
NCT04684368Phase 2

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Recruiting
NCT03670966Phase 1

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

Recruiting
NCT00641381Phase 1

Carmustine, Etoposide, Cyclophosphamide, and Stem Cell Transplant in Treating Patients With HIV-Associated Lymphoma

Completed
NCT01231412Phase 3

Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

Completed
NCT07225985Phase 1

Pralatrexate With Bendamustine and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma

Recruiting
NCT00114101Phase 3

Lenalidomide in Treating Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplant

Active Not Recruiting
NCT01857934Phase 2

Therapy for Children With Advanced Stage Neuroblastoma

Completed
NCT02250937Phase 2

Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

Active Not Recruiting
NCT03856216Phase 2

Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation

Terminated
NCT00083135Phase 1

N2000-01: Double Infusion of Iodine I 131 Metaiodobenzylguanidine Followed by Autologous Stem Cell Transplantation

Completed
NCT00792948Phase 2

Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT02333162Phase 1

Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

Suspended
NCT00576979Phase 1

Intensity-Modulated Radiation Therapy, Etoposide, and Cyclophosphamide Followed By Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

Completed
NCT06752694Phase 2

Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic Anemia

Recruiting
NCT04965597Phase 2

Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

Completed
NCT00716066Phase 2

Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases

Active Not Recruiting
NCT00003042Phase 2

Chemotherapy and Stem Cell Transplantation in Treating Patients With Stage IIIB Breast Cancer

Completed
NCT04370301Phase 2

Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis

Recruiting
NCT01746849Phase 2

Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

Active Not Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
478