Success Metrics

Clinical Success Rate
88.5%

Based on 337 completed trials

Completion Rate
88%(337/381)
Active Trials
17(4%)
Results Posted
35%(117 trials)
Terminated
44(9%)

Phase Distribution

Ph phase_1
149
31%
Ph phase_3
64
13%
Ph not_applicable
24
5%
Ph phase_4
1
0%
Ph phase_2
237
49%
Ph early_phase_1
2
0%

Phase Distribution

151

Early Stage

237

Mid Stage

65

Late Stage

Phase Distribution477 total trials
Early Phase 1First-in-human
2(0.4%)
Phase 1Safety & dosage
149(31.2%)
Phase 2Efficacy & side effects
237(49.7%)
Phase 3Large-scale testing
64(13.4%)
Phase 4Post-market surveillance
1(0.2%)
N/ANon-phased studies
24(5.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

82.6%

337 of 408 finished

Non-Completion Rate

17.4%

71 ended early

Currently Active

17

trials recruiting

Total Trials

479

all time

Status Distribution
Active(18)
Completed(337)
Terminated(71)
Other(53)

Detailed Status

Completed337
unknown52
Terminated44
Withdrawn27
Active, not recruiting11
Recruiting6

Development Timeline

Analytics

Development Status

Total Trials
479
Active
17
Success Rate
88.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (0.4%)
Phase 1149 (31.2%)
Phase 2237 (49.7%)
Phase 364 (13.4%)
Phase 41 (0.2%)
N/A24 (5.0%)

Trials by Status

active_not_recruiting112%
completed33770%
not_yet_recruiting10%
recruiting61%
suspended10%
terminated449%
unknown5211%
withdrawn276%

Recent Activity

Clinical Trials (479)

Showing 20 of 479 trialsScroll for more
NCT00114101Phase 3

Lenalidomide in Treating Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplant

Active Not Recruiting
NCT03259503Phase 1

Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant

Completed
NCT00792948Phase 2

Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03626285

Bone Marrow Transplantation Using CD34-Selected Stem Cells From Related or Unrelated Donors in Treating Participants With Cancer or Other Disorders

Unknown
NCT04370301Phase 2

Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis

Recruiting
NCT03670966Phase 1

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

Recruiting
NCT03128034Phase 1

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

Recruiting
NCT03622788Phase 1

Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant

Active Not Recruiting
NCT00534430Phase 2

Busulfan, Etoposide, and Total-Body Irradiation in Treating Patients Undergoing Donor Stem Cell or Bone Marrow Transplant for Advanced Hematologic Cancer

Completed
NCT05364762Phase 2

Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants

Active Not Recruiting
NCT00544115Phase 2

Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

Active Not Recruiting
NCT02220985Phase 2

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

Completed
NCT06752694Phase 2

Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic Anemia

Active Not Recruiting
NCT02797470Phase 1

Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant

Active Not Recruiting
NCT07582172Phase 2

Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome

Not Yet Recruiting
NCT07225985Phase 1

Pralatrexate With Bendamustine and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma

Recruiting
NCT04684368Phase 2

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Recruiting
NCT01318317Phase 1

Genetically Engineered Lymphocyte Therapy After Peripheral Blood Stem Cell Transplant in Treating Patients With High-Risk, Intermediate-Grade, B-cell Non-Hodgkin Lymphoma

Active Not Recruiting
NCT00641381Phase 1

Carmustine, Etoposide, Cyclophosphamide, and Stem Cell Transplant in Treating Patients With HIV-Associated Lymphoma

Completed
NCT01231412Phase 3

Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

Completed

Drug Details

Intervention Type
PROCEDURE
Total Trials
479