Success Metrics

Clinical Success Rate
92.7%

Based on 38 completed trials

Completion Rate
93%(38/41)
Active Trials
0(0%)
Results Posted
13%(5 trials)
Terminated
3(7%)

Phase Distribution

Ph phase_1
17
41%
Ph phase_2
21
51%
Ph phase_3
2
5%
Ph not_applicable
1
2%

Phase Distribution

17

Early Stage

21

Mid Stage

2

Late Stage

Phase Distribution41 total trials
Phase 1Safety & dosage
17(41.5%)
Phase 2Efficacy & side effects
21(51.2%)
Phase 3Large-scale testing
2(4.9%)
N/ANon-phased studies
1(2.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

92.7%

38 of 41 finished

Non-Completion Rate

7.3%

3 ended early

Currently Active

0

trials recruiting

Total Trials

41

all time

Status Distribution
Completed(38)
Terminated(3)

Detailed Status

Completed38
Terminated3

Development Timeline

Analytics

Development Status

Total Trials
41
Active
0
Success Rate
92.7%
Most Advanced
Phase 3

Trials by Phase

Phase 117 (41.5%)
Phase 221 (51.2%)
Phase 32 (4.9%)
N/A1 (2.4%)

Trials by Status

completed3893%
terminated37%

Recent Activity

Clinical Trials (41)

Showing 20 of 41 trialsScroll for more
NCT00053781Phase 2

Perifosine in Treating Patients With Metastatic or Recurrent Malignant Melanoma

Completed
NCT00053794Phase 2

Perifosine in Treating Patients With Metastatic or Locally Advanced Soft Tissue Sarcoma

Completed
NCT02238496Phase 1

Perifosine and Torisel (Temsirolimus) for Recurrent/Progressive Malignant Gliomas

Completed
NCT01051557Phase 1

Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma

Completed
NCT00590954Phase 2

Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomas

Completed
NCT00005794Phase 1

Perifosine in Treating Patients With Advanced Solid Tumors

Completed
NCT01048580Phase 1

Study of Perifosine + Capecitabine for Colon Cancer Patients

Completed
NCT00847366Not Applicable

Open Label Trial of Perifosine in Patients Currently Being Treated on Perifosine Trials in Solid Tumors or Multiple Myeloma

Completed
NCT00398710Phase 2

A Phase II Study of Perifosine in Patients With Relapsed/Refractory Waldenström's Macroglobulinemia

Completed
NCT00391560Phase 2

Phase II Study of Perifosine in Patients With Refractory and Relapsed Leukemia

Completed
NCT01224730Phase 1

A Food Effect and QTc Study of Perifosine in Patients With Advanced Malignancies

Completed
NCT00398879Phase 2

Placebo-Controlled Study of Perifosine + Single Agent Chemotherapy for Metastatic Cancer Patients

Completed
NCT00389077Phase 2

Trial of Two Schedules of Perifosine for Patients With Solid Tumors or Lymphomas

Completed
NCT00401388Phase 2

A Trial of Perifosine in Patients With Chemo-Insensitive Sarcomas

Completed
NCT00448721Phase 2

A Phase II Trial of Perifosine Following Tyrosine Kinase Inhibitor (TKI) - Failure in Patients With Renal Cancer

Completed
NCT00375791Phase 2

Efficacy of Perifosine Alone and in Combination With Dexamethasone for Patients With Multiple Myeloma

Completed
NCT00401011Phase 1

Safety & Efficacy Study of Perifosine + Bortezomib +/- Dexamethasone for Multiple Myeloma Patients

Completed
NCT00399789Phase 1

A Phase 1/2 Trial of Perifosine in the Treatment of Non-Small Cell Lung Cancer

Completed
NCT00455559Phase 2

Ph II Study of Perifosine Plus Gleevec for Patients With GIST

Completed
NCT01002248Phase 3

Assessment of Efficacy and Safety of Perifosine, Bortezomib and Dexamethasone in Multiple Myeloma Patients

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
41