Success Metrics

Clinical Success Rate
87.5%

Based on 28 completed trials

Completion Rate
88%(28/32)
Active Trials
6(15%)
Results Posted
96%(27 trials)
Terminated
4(10%)

Phase Distribution

Ph phase_1
9
23%
Ph phase_3
3
8%
Ph phase_2
27
69%

Phase Distribution

9

Early Stage

27

Mid Stage

3

Late Stage

Phase Distribution39 total trials
Phase 1Safety & dosage
9(23.1%)
Phase 2Efficacy & side effects
27(69.2%)
Phase 3Large-scale testing
3(7.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

84.8%

28 of 33 finished

Non-Completion Rate

15.2%

5 ended early

Currently Active

6

trials recruiting

Total Trials

39

all time

Status Distribution
Active(6)
Completed(28)
Terminated(5)

Detailed Status

Completed28
Active, not recruiting5
Terminated4
Recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
39
Active
6
Success Rate
87.5%
Most Advanced
Phase 3

Trials by Phase

Phase 19 (23.1%)
Phase 227 (69.2%)
Phase 33 (7.7%)

Trials by Status

completed2872%
active_not_recruiting513%
recruiting13%
terminated410%
withdrawn13%

Recent Activity

Clinical Trials (39)

Showing 20 of 39 trialsScroll for more
NCT03077542Phase 1

Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

Active Not Recruiting
NCT03663933Phase 2

Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation

Active Not Recruiting
NCT03249831Phase 1

A Blood Stem Cell Transplant for Sickle Cell Disease

Active Not Recruiting
NCT05757310Phase 1

A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia

Recruiting
NCT03112603Phase 3

A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)

Completed
NCT01059786Phase 2

Randomized Phase II Trial of Rituximab With Either Pentostatin or Bendamustine for Multiply Relapsed or Refractory Hairy Cell Leukemia

Active Not Recruiting
NCT01352312Phase 1

Combination of Pentostatin, Bendamustine and Ofatumumab for Treatment of Chronic Lymphocytic Leukemia and Lymphoma

Terminated
NCT02105766Phase 2

Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

Active Not Recruiting
NCT00571662Phase 2

Safety and Efficacy of Pentostatin and Low Dose TBI With Allogenic Peripheral Blood Stem Cell Transplant

Completed
NCT00816413Phase 1

Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological Cancer

Withdrawn
NCT00074282Phase 2

Pentostatin, Cyclophosphamide, and Rituximab Followed By Campath-1H in Patients With Relapsed or Refractory B-Cell CLL

Completed
NCT00045305Phase 2

Reduced-Intensity Regimen Before Donor Bone Marrow Transplant in Treating Patients With Myelodysplastic Syndromes

Completed
NCT00057954Phase 2

Reduced-Intensity Regimen Before Allogeneic Transplant for Patients With Relapsed Non-Hodgkin's or Hodgkin's Lymphoma

Terminated
NCT00074035Phase 2

Pentostatin in Treating Patients With Refractory Chronic Graft-Versus-Host Disease

Completed
NCT00224874Phase 2

Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302)

Completed
NCT00096161Phase 2

Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell Transplant

Completed
NCT00602836Phase 2

Rituximab, Pentostatin, Cyclophosphamide, and Lenalidomide in Treating Patients With Previously Untreated B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Completed
NCT01362790Phase 1

SS1P and Pentostatin Plus Cyclophosphamide for Mesothelioma

Completed
NCT01024010Phase 2

Ofatumumab, Pentostatin, and Cyclophosphamide in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Completed
NCT00923845Phase 2

Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney Cancer

Completed

Drug Details

Intervention Type
DRUG
Total Trials
39