Success Metrics

Clinical Success Rate
73.7%

Based on 14 completed trials

Completion Rate
74%(14/19)
Active Trials
3(10%)
Results Posted
86%(12 trials)
Terminated
5(17%)

Phase Distribution

Ph phase_1
14
48%
Ph phase_3
4
14%
Ph phase_2
10
34%

Phase Distribution

14

Early Stage

10

Mid Stage

4

Late Stage

Phase Distribution28 total trials
Phase 1Safety & dosage
14(50.0%)
Phase 2Efficacy & side effects
10(35.7%)
Phase 3Large-scale testing
4(14.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

58.3%

14 of 24 finished

Non-Completion Rate

41.7%

10 ended early

Currently Active

3

trials recruiting

Total Trials

29

all time

Status Distribution
Active(4)
Completed(14)
Terminated(10)
Other(1)

Detailed Status

Completed14
Withdrawn5
Terminated5
Active, not recruiting3
Not yet recruiting1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
29
Active
3
Success Rate
73.7%
Most Advanced
Phase 3

Trials by Phase

Phase 114 (50.0%)
Phase 210 (35.7%)
Phase 34 (14.3%)

Trials by Status

not_yet_recruiting13%
withdrawn517%
unknown13%
active_not_recruiting310%
completed1448%
terminated517%

Recent Activity

Clinical Trials (29)

Showing 20 of 29 trialsScroll for more
NCT04809467Phase 1

A Study Evaluating Safety, PK, and Efficacy of Tafasitamab and Parsaclisib in Participants With Relapsed/Refractory Non Hodgkin Lymphoma (R/R NHL) or Chronic Lymphocytic Leukemia (CLL)

Terminated
NCT04323956Phase 1

Parsaclisib Plus the Standard Drug Therapy in Patients With Newly Diagnosed, High Risk Diffuse Large B-cell Lymphoma

Active Not Recruiting
NCT04661007Phase 1

To Assess the Safety and Tolerability of Tafasitamab Alone or in Combination With Other Drugs in Japanese Participants With Non-Hodgkins Lymphoma (NHL)

Active Not Recruiting
NCT04509700Phase 2

Rollover Study to Provide Continued Treatment for Participants With B-Cell Malignancies Previously Enrolled in Studies of Parsaclisib (INCB050465)

Active Not Recruiting
NCT05083208Phase 1

PI3Kδ Inhibitor Parsaclisib Combined With Chidamide for the Treatment of Relapsed/Refractory Peripheral T-cell Lymphoma

Terminated
NCT04551066Phase 3

To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)

Terminated
NCT04551053Phase 3

To Evaluate Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis Who Have Suboptimal Response to Ruxolitinib (LIMBER-304)

Terminated
NCT07149818

A Single-arm Phase 2 Prospective Clinical Study of Linprixel in the Treatment of Relapsed/Refractory Autoimmune Hemolytic Anemia

Not Yet Recruiting
NCT02998476Phase 2

A Phase 2 Safety and Efficacy Study of INCB050465 in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (CITADEL-202)

Completed
NCT03424122Phase 1

INCB050465 in Combination With Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)

Completed
NCT03039114Phase 1

Study Evaluating Safety and Efficacy of INCB050465 Combined With Bendamustine and Obinutuzumab in Relapsed or Refractory Follicular Lymphoma (CITADEL-102)

Completed
NCT03538041Phase 2

A Study of INCB050465 in Participants With Autoimmune Hemolytic Anemia

Completed
NCT03144674Phase 2

A Study of INCB050465 in Subjects With Relapsed or Refractory Marginal Zone Lymphoma (CITADEL-204)

Completed
NCT03235544Phase 2

A Study of INCB050465 in Relapsed or Refractory Mantle Cell Lymphoma Previously Treated With or Without a Bruton's Tyrosine Kinase (BTK) Inhibitor

Completed
NCT03126019Phase 2

A Study of INCB050465 in Relapsed or Refractory Follicular Lymphoma

Completed
NCT04774068Phase 1

Romidepsin and Parsaclisib for the Treatment of Relapsed or Refractory T-Cell Lymphomas

Completed
NCT04434937Phase 2

Open-Label Study of Parsaclisib, in Japanese Participants With Relapsed or Refractory Follicular Lymphoma (CITADEL-213)

Completed
NCT02718300Phase 2

A Study of INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis

Terminated
NCT05867030Phase 1

Parsaclisib in Patients With Relapsed or Refractory Follicular Lymphoma

Withdrawn
NCT02018861Phase 1

A Phase 1/2, Open-Label, Dose Escalation, Safety and Tolerability Study of INCB050465 and Itacitinib in Subjects With Previously Treated B-Cell Malignancies (CITADEL-101)

Completed

Drug Details

Intervention Type
DRUG
Total Trials
29