Success Metrics

Clinical Success Rate
82.7%

Based on 1,139 completed trials

Completion Rate
83%(1139/1377)
Active Trials
437(20%)
Results Posted
59%(671 trials)
Terminated
238(11%)

Phase Distribution

Ph phase_4
15
1%
Ph not_applicable
34
2%
Ph early_phase_1
11
1%
Ph phase_2
1,007
47%
Ph phase_1
586
27%
Ph phase_3
477
22%

Phase Distribution

597

Early Stage

1007

Mid Stage

492

Late Stage

Phase Distribution2130 total trials
Early Phase 1First-in-human
11(0.5%)
Phase 1Safety & dosage
586(27.5%)
Phase 2Efficacy & side effects
1,007(47.3%)
Phase 3Large-scale testing
477(22.4%)
Phase 4Post-market surveillance
15(0.7%)
N/ANon-phased studies
34(1.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.4%

1139 of 1452 finished

Non-Completion Rate

21.6%

313 ended early

Currently Active

437

trials recruiting

Total Trials

2,161

all time

Status Distribution
Active(486)
Completed(1139)
Terminated(313)
Other(223)

Detailed Status

Completed1139
Terminated238
Recruiting230
unknown215
Active, not recruiting207
Withdrawn75

Development Timeline

Analytics

Development Status

Total Trials
2161
Active
437
Success Rate
82.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 111 (0.5%)
Phase 1586 (27.5%)
Phase 21007 (47.3%)
Phase 3477 (22.4%)
Phase 415 (0.7%)
N/A34 (1.6%)

Trials by Status

enrolling_by_invitation30%
recruiting23011%
suspended80%
not_yet_recruiting462%
unknown21510%
active_not_recruiting20710%
completed113953%
terminated23811%
withdrawn753%

Recent Activity

Clinical Trials (2,161)

Showing 20 of 2,161 trialsScroll for more
NCT04267848Phase 3

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Recruiting
NCT07743164Phase 3

A Clinical Trial of Raludotatug Deruxtecan (R-DXd) With or Without Bevacizumab in Participants With Ovarian Cancer Who Have Progressed During Treatment With PARP-inhibitors Treatment on First Line Maintenance (MK-5909-008/ENGOT-ov107/GOG-3142 / REJOICE-Ovarian05)

Not Yet Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT06203600Phase 2

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Recruiting
NCT06623422Phase 3

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Recruiting
NCT06058377Phase 3

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Recruiting
NCT07063745Phase 2

A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Recruiting
NCT04892953Phase 2

Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy

Recruiting
NCT06926868Phase 2

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Recruiting
NCT04253964Phase 2

Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy

Recruiting
NCT06448754Phase 2

Volrustomig Priming Regimens Exploratory Phase II Platform Study

Recruiting
NCT07198074Phase 3

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Recruiting
NCT07756645Phase 3

A Study to Assess Intravenous ABBV-1480 Combined With Chemotherapy Versus Pembrolizumab Combined With Chemotherapy for the First Line Treatment of Locally Advanced/Metastatic Non-Small Cell Lung Cancer in Adult Participants

Not Yet Recruiting
NCT06161441Phase 2

A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemotherapy in Adult Patients With Non-Small Cell Lung Cancer That Can be Treated With Surgery

Active Not Recruiting
NCT07060807Phase 3

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Recruiting
NCT04001829Phase 2

Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer

Active Not Recruiting
NCT07419295Phase 3

A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)

Recruiting
NCT07216703Phase 3

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

Recruiting
NCT04269200Phase 3

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
2,161