Success Metrics

Clinical Success Rate
83.1%

Based on 1,121 completed trials

Completion Rate
83%(1121/1349)
Active Trials
433(20%)
Results Posted
58%(652 trials)
Terminated
228(11%)

Phase Distribution

Ph phase_2
999
47%
Ph not_applicable
34
2%
Ph phase_3
471
22%
Ph phase_4
14
1%
Ph phase_1
583
27%
Ph early_phase_1
11
1%

Phase Distribution

594

Early Stage

999

Mid Stage

485

Late Stage

Phase Distribution2112 total trials
Early Phase 1First-in-human
11(0.5%)
Phase 1Safety & dosage
583(27.6%)
Phase 2Efficacy & side effects
999(47.3%)
Phase 3Large-scale testing
471(22.3%)
Phase 4Post-market surveillance
14(0.7%)
N/ANon-phased studies
34(1.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.7%

1121 of 1424 finished

Non-Completion Rate

21.3%

303 ended early

Currently Active

433

trials recruiting

Total Trials

2,143

all time

Status Distribution
Active(486)
Completed(1121)
Terminated(303)
Other(233)

Detailed Status

Completed1121
Terminated228
unknown225
Recruiting222
Active, not recruiting211
Withdrawn75

Development Timeline

Analytics

Development Status

Total Trials
2143
Active
433
Success Rate
83.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 111 (0.5%)
Phase 1583 (27.6%)
Phase 2999 (47.3%)
Phase 3471 (22.3%)
Phase 414 (0.7%)
N/A34 (1.6%)

Trials by Status

enrolling_by_invitation20%
not_yet_recruiting512%
unknown22510%
active_not_recruiting21110%
completed112152%
suspended80%
terminated22811%
recruiting22210%
withdrawn753%

Recent Activity

Clinical Trials (2,143)

Showing 20 of 2,143 trialsScroll for more
NCT06058377Phase 3

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Recruiting
NCT05256225Phase 3

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Recruiting
NCT05296798Phase 3

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

Active Not Recruiting
NCT07061977Phase 3

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Recruiting
NCT01187199Phase 1

Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer

Active Not Recruiting
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Not Yet Recruiting
NCT04615013Phase 1

NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT07060807Phase 3

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Recruiting
NCT06741644Phase 1

A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors

Recruiting
NCT06524544Phase 3

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Recruiting
NCT06712316Phase 2

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

Recruiting
NCT06946797Phase 2

A Study to Evaluate Two Dosing Regimens of Subcutaneous Nivolumab in Combination With Intravenous Ipilimumab and Chemotherapy in Participants With Previously Untreated Metastatic or Recurrent Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT05039801Phase 1

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

Recruiting
NCT06203600Phase 2

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Recruiting
NCT04220827Phase 1

Paclitaxel for the Treatment of Gastric or Gastroesophageal Cancer

Active Not Recruiting
NCT02876107Phase 2

Carboplatin and Paclitaxel With or Without Panitumumab in Treating Patients With Invasive Triple Negative Breast Cancer

Active Not Recruiting
NCT05635708Phase 2

A Study of Tislelizumab in Combination With Investigational Agents in Participants With Non-Small Cell Lung Cancer

Active Not Recruiting
NCT04267848Phase 3

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Recruiting
NCT07020065Phase 2

Reduced-dose Carboplatin-doublet-chemotherapy + Cemiplimab vs Cemiplimab Monotherapy in Treatment Naive Older and Frail Patients With Metastatic NSCLC With PD-L1 <50%

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
2,143