Success Metrics

Clinical Success Rate
100.0%

Based on 1 completed trials

Completion Rate
100%(1/1)
Active Trials
34(63%)
Results Posted
0%(0 trials)

Phase Distribution

Ph phase_1
5
9%
Ph phase_2
32
59%
Ph phase_4
1
2%
Ph not_applicable
3
6%
Ph phase_3
9
17%

Phase Distribution

5

Early Stage

32

Mid Stage

10

Late Stage

Phase Distribution50 total trials
Phase 1Safety & dosage
5(10.0%)
Phase 2Efficacy & side effects
32(64.0%)
Phase 3Large-scale testing
9(18.0%)
Phase 4Post-market surveillance
1(2.0%)
N/ANon-phased studies
3(6.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

100.0%

1 of 1 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

34

trials recruiting

Total Trials

54

all time

Status Distribution
Active(40)
Completed(1)
Other(13)

Detailed Status

Recruiting29
unknown13
Not yet recruiting6
Active, not recruiting5
Completed1

Development Timeline

Analytics

Development Status

Total Trials
54
Active
34
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (10.0%)
Phase 232 (64.0%)
Phase 39 (18.0%)
Phase 41 (2.0%)
N/A3 (6.0%)

Trials by Status

unknown1324%
active_not_recruiting59%
not_yet_recruiting611%
recruiting2954%
completed12%

Recent Activity

Clinical Trials (54)

Showing 20 of 54 trialsScroll for more
NCT07299019Phase 3

A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

Recruiting
NCT07554898Phase 2

Ultra-low-dose Radiation Therapy Followed by Orelabrutinib as First-line Treatment for Stage Ⅰ-Ⅱ MALT Lymphoma: A Prospective, Multicenter Phase Ⅱ Study

Recruiting
NCT04989621Phase 2

Orelabrutinib Plus Rituximab Followed by Maintenance With Orelabrutinib for Relapsed and Refractory Follicular Lymphoma(RR FL)

Recruiting
NCT07480863Phase 2

Treatment of Orelabrutinib+Hi-CVP Regimen for Previously Untreated MZL

Active Not Recruiting
NCT07499271Phase 2

Genetic Subtype-matched Targeted Therapy for the Treatment of Newly Diagnosed DLBCL With TP53 Mutation

Recruiting
NCT06793189Phase 2

MZL-IPI Risk-adapted Targeted Therapy in Untreated MZL

Recruiting
NCT07448324Phase 2

Orelabrutinib Combined With Rituximab ± Lenalidomide in Response-Adapted Stratified Therapy for Untreated MZL

Recruiting
NCT07441993Phase 2

Exploratory Study of Orelabrutinib in the Treatment of Early-stage Untreated MZL

Recruiting
NCT06583837Phase 2

Orelabrutinib Followed by Response-adapted Ultra-low Dose 4Gy Radiation as First-line Treatment of MALT Lymphoma

Active Not Recruiting
NCT07410520Phase 2

PD-1 Inhibitor Combined With Rituximab, Methotrexate, and Orelabrutinib (PD-1i+RMO) for Newly Diagnosed PCNSL and SCNSL.

Recruiting
NCT07400250Phase 2

Phase II Study of Orelabrutinib in Combination With Romiplostim N01 in Patients With Primary Immune Thrombocytopenia (ITP) Who Have Received At Least One Prior Line of Therapy

Not Yet Recruiting
NCT07377578Phase 3

A Study of Rocbrutinib Versus Investigator's Choice of BTK Inhibitors in Patients With Relapsed or Refractory Mantle Cell Lymphoma

Recruiting
NCT07355699Phase 4

Application of Orelabrutinib With or Without CD20 Monoclonal Antibody in Previously Untreated Marginal Zone Lymphoma

Recruiting
NCT07272499Phase 2

Orelabrutinib Plus Lisaftoclax and Rituximab in Untreated Mantle Cell Lymphoma With High-Risk Disease

Recruiting
NCT07067463Phase 3

A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

Recruiting
NCT07257510Not Applicable

Pomalidomide Plus Orelabrutinib and Zuberitamab in Untreated Mantle Cell Lymphoma

Recruiting
NCT06378138Phase 2

ICP-248 in Combination With Orelabrutinib in Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (APEX-03)

Recruiting
NCT07208981Phase 2

Orelabrutinib Combined With Zebetuzumab and Lenalidomide for the Treatment of Newly Diagnosed MZL

Recruiting
NCT07199296Phase 2

Orelabrutinib and Rituximab With Optional Autologous Hematopoietic Stem Cell Transplantation in MCL Treatment

Recruiting
NCT07185373Phase 2

Orelabrutinib Combined With Teniposide, Rituximab and Methotrexate for Newly Diagnosed PCNSL

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
54