Success Metrics

Clinical Success Rate
100.0%

Based on 1 completed trials

Completion Rate
100%(1/1)
Active Trials
35(61%)
Results Posted
0%(0 trials)

Phase Distribution

Ph phase_2
34
60%
Ph phase_1
5
9%
Ph phase_3
10
18%
Ph phase_4
1
2%
Ph not_applicable
3
5%

Phase Distribution

5

Early Stage

34

Mid Stage

11

Late Stage

Phase Distribution53 total trials
Phase 1Safety & dosage
5(9.4%)
Phase 2Efficacy & side effects
34(64.2%)
Phase 3Large-scale testing
10(18.9%)
Phase 4Post-market surveillance
1(1.9%)
N/ANon-phased studies
3(5.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

100.0%

1 of 1 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

35

trials recruiting

Total Trials

57

all time

Status Distribution
Active(43)
Completed(1)
Other(13)

Detailed Status

Recruiting30
unknown13
Not yet recruiting8
Active, not recruiting5
Completed1

Development Timeline

Analytics

Development Status

Total Trials
57
Active
35
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (9.4%)
Phase 234 (64.2%)
Phase 310 (18.9%)
Phase 41 (1.9%)
N/A3 (5.7%)

Trials by Status

unknown1323%
active_not_recruiting59%
not_yet_recruiting814%
completed12%
recruiting3053%

Recent Activity

Clinical Trials (57)

Showing 20 of 57 trialsScroll for more
NCT07299019Phase 3

A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

Recruiting
NCT07067463Phase 3

A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

Recruiting
NCT07272499Phase 2

Orelabrutinib Plus Lisaftoclax and Rituximab in Untreated Mantle Cell Lymphoma With High-Risk Disease

Recruiting
NCT07719556Phase 2

Orelabrutinib Combined With Obinutuzumab and Short-Course Venetoclax in Patients With Treatment-Naïve Mantle Cell Lymphoma (MCL)

Recruiting
NCT07719855Phase 3

A Multicenter, Prospective, Open-Label, Randomized Controlled Clinical Study of Orelabrutinib Combined With Obinutuzumab and Lenalidomide Versus Obinutuzumab Plus Chemotherapy for Treatment-Naive Follicular Lymphoma

Not Yet Recruiting
NCT07585747Phase 2

A Exploratory Study on Untreated Follicular Lymphoma With Orelabrutinib, Tafasitamab, and Lenalidomide

Not Yet Recruiting
NCT07554898Phase 2

Ultra-low-dose Radiation Therapy Followed by Orelabrutinib as First-line Treatment for Stage Ⅰ-Ⅱ MALT Lymphoma

Recruiting
NCT04989621Phase 2

Orelabrutinib Plus Rituximab Followed by Maintenance With Orelabrutinib for Relapsed and Refractory Follicular Lymphoma(RR FL)

Recruiting
NCT07480863Phase 2

Treatment of Orelabrutinib+Hi-CVP Regimen for Previously Untreated MZL

Active Not Recruiting
NCT07499271Phase 2

Genetic Subtype-matched Targeted Therapy for the Treatment of Newly Diagnosed DLBCL With TP53 Mutation

Recruiting
NCT06793189Phase 2

MZL-IPI Risk-adapted Targeted Therapy in Untreated MZL

Recruiting
NCT07448324Phase 2

Orelabrutinib Combined With Rituximab ± Lenalidomide in Response-Adapted Stratified Therapy for Untreated MZL

Recruiting
NCT07441993Phase 2

Exploratory Study of Orelabrutinib in the Treatment of Early-stage Untreated MZL

Recruiting
NCT06583837Phase 2

Orelabrutinib Followed by Response-adapted Ultra-low Dose 4Gy Radiation as First-line Treatment of MALT Lymphoma

Active Not Recruiting
NCT07410520Phase 2

PD-1 Inhibitor Combined With Rituximab, Methotrexate, and Orelabrutinib (PD-1i+RMO) for Newly Diagnosed PCNSL and SCNSL.

Recruiting
NCT07400250Phase 2

Phase II Study of Orelabrutinib in Combination With Romiplostim N01 in Patients With Primary Immune Thrombocytopenia (ITP) Who Have Received At Least One Prior Line of Therapy

Not Yet Recruiting
NCT07377578Phase 3

A Study of Rocbrutinib Versus Investigator's Choice of BTK Inhibitors in Patients With Relapsed or Refractory Mantle Cell Lymphoma

Recruiting
NCT07355699Phase 4

Application of Orelabrutinib With or Without CD20 Monoclonal Antibody in Previously Untreated Marginal Zone Lymphoma

Recruiting
NCT07257510Not Applicable

Pomalidomide Plus Orelabrutinib and Zuberitamab in Untreated Mantle Cell Lymphoma

Recruiting
NCT06378138Phase 2

ICP-248 in Combination With Orelabrutinib in Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (APEX-03)

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
57