Success Metrics

Clinical Success Rate
66.7%

Based on 4 completed trials

Completion Rate
67%(4/6)
Active Trials
2(17%)
Results Posted
125%(5 trials)
Terminated
2(17%)

Phase Distribution

Ph phase_2
4
33%
Ph early_phase_1
1
8%
Ph phase_4
1
8%
Ph phase_3
5
42%

Phase Distribution

1

Early Stage

4

Mid Stage

6

Late Stage

Phase Distribution11 total trials
Early Phase 1First-in-human
1(9.1%)
Phase 2Efficacy & side effects
4(36.4%)
Phase 3Large-scale testing
5(45.5%)
Phase 4Post-market surveillance
1(9.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

40.0%

4 of 10 finished

Non-Completion Rate

60.0%

6 ended early

Currently Active

2

trials recruiting

Total Trials

12

all time

Status Distribution
Active(2)
Completed(4)
Terminated(6)

Detailed Status

Completed4
Withdrawn4
Active, not recruiting2
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
12
Active
2
Success Rate
66.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (9.1%)
Phase 24 (36.4%)
Phase 35 (45.5%)
Phase 41 (9.1%)

Trials by Status

active_not_recruiting217%
completed433%
withdrawn433%
terminated217%

Recent Activity

Clinical Trials (12)

Showing 12 of 12 trials
NCT03045029

ADAPT - A Patient Registry of the Real-world Use of Orenitram®

Active Not Recruiting
NCT05203510Phase 4

A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial Hypertension

Active Not Recruiting
NCT02276872Phase 2

Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years

Completed
NCT02583789Early Phase 1

Assess Efficacy of of Oral Treprostinil in Patients With Symptomatic Primary or Secondary Raynaud's Phenomenon

Completed
NCT02663895Phase 2

Safety and Efficacy of Oral Treprostinil in the Treatment of Calcinosis in Patients With Systemic Sclerosis

Completed
NCT01027949Phase 3

An Open-Label Extension Trial of UT-15C Sustained-release (SR) in Subjects With Pulmonary Arterial Hypertension

Completed
NCT03037580Phase 3

Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction

Terminated
NCT03043651Phase 3

Open-label Extension of Oral Treprostinil in Subjects With PH Associated With HFpEF

Terminated
NCT02999906Phase 3

Study to Compare Triple Therapy (Oral Treprostinil, Ambrisentan, and Tadalafil) With Dual Therapy (Ambrisentan, Tadalafil, and Placebo) in Subjects With Pulmonary Arterial Hypertension

Withdrawn
NCT03016468Phase 2

Safety of Transition From Selexipag to Remodulin® Then Oral Treprostinil in Symptomatic Adult PAH

Withdrawn
NCT03055234Phase 3

Study to Evaluate Efficacy and Safety of Oral Treprostinil in Subjects With Pulmonary Hypertension (PH) Associated With Sickle Cell Disease (SCD)

Withdrawn
NCT02603068Phase 2

Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis

Withdrawn

All 12 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
12