Success Metrics

Clinical Success Rate
100.0%

Based on 1 completed trials

Completion Rate
100%(1/1)
Active Trials
13(62%)
Results Posted
0%(0 trials)

Phase Distribution

Ph not_applicable
3
14%
Ph phase_2
7
33%
Ph early_phase_1
1
5%
Ph phase_1
3
14%
Ph phase_3
5
24%

Phase Distribution

4

Early Stage

7

Mid Stage

5

Late Stage

Phase Distribution19 total trials
Early Phase 1First-in-human
1(5.3%)
Phase 1Safety & dosage
3(15.8%)
Phase 2Efficacy & side effects
7(36.8%)
Phase 3Large-scale testing
5(26.3%)
N/ANon-phased studies
3(15.8%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

1 of 1 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

13

trials recruiting

Total Trials

21

all time

Status Distribution
Active(17)
Completed(1)
Other(3)

Detailed Status

Recruiting12
Not yet recruiting4
unknown3
Completed1
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
21
Active
13
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (5.3%)
Phase 13 (15.8%)
Phase 27 (36.8%)
Phase 35 (26.3%)
N/A3 (15.8%)

Trials by Status

recruiting1257%
not_yet_recruiting419%
completed15%
unknown314%
active_not_recruiting15%

Recent Activity

Clinical Trials (21)

Showing 20 of 21 trialsScroll for more
NCT07178912Phase 2

Phase II Study of the Combination of Subcutaneous Blinatumomab and Olverembatinib in Patients With Philadelphia Chromosome (ph)-Positive and/or BCR::ABL1 Positive Acute Lymphoblastic Leukemia (ALL)

Not Yet Recruiting
NCT06051409Phase 3

A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)

Recruiting
NCT04501120Phase 1

Study of Lisaftoclax (APG-2575) Single Agent and Combination With Therapy in Patients Relapsed/Refractory AML

Recruiting
NCT06401603Phase 1

A Phase I Study of Decitabine, Lisaftoclax, and Olverembatinib in Patients With Advanced Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Myeloid Leukemia

Recruiting
NCT06817720Phase 2

Phase II Study Assessing the Efficacy and Toxicity of Olverembatinib Monotherapy in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase

Recruiting
NCT07454226Not Applicable

ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALL

Not Yet Recruiting
NCT07493161Not Applicable

Chemotherapy With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALL

Not Yet Recruiting
NCT06481228Not Applicable

Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL

Recruiting
NCT07152041Phase 3

Newly-diagnosed Pediatric Ph-positive B-ALL Protocol

Recruiting
NCT07074496Early Phase 1

Efficacy, Safety, and Pharmacokinetics of ThisCART19A Combined With Olverembatinib in Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia.

Active Not Recruiting
NCT06390306

The Efficacy and Safety of Third-generation TKIs Combined With Azacitidine and Bcl-2 Inhibitor in Patients With CML-MBP

Recruiting
NCT06423911Phase 3

Study of Olverembatinib (HQP1351) in Patients With CP-CML

Recruiting
NCT05594784Phase 2

Olverembatinib Combined With Reduced-Intensity Chemotherapy and Venetoclax for de Novo Ph+ ALL

Completed
NCT06757855Phase 1

Olverembatinib Combined With Venetoclax and Azacitidine in Blast Phase Ph Chromosome-positive CML

Recruiting
NCT06754267Phase 2

Venetoclax Combined With Olverembatinib and Predinisone in Treating Ph+ B-ALL

Recruiting
NCT06640361Phase 3

A Study of Olverembatinib in SDH-deficient GIST.

Recruiting
NCT05594758

Named Patient Program for Olverembatinib (HQP1351)

Unknown
NCT05931757Phase 2

A Study of Olverembatinib Combined With Blinatumomab in the Treatment of Ph+ ALL

Not Yet Recruiting
NCT05466175Phase 2

A Study of Olverembatinib in the Treatment of Ph+ ALL

Unknown
NCT05521204Phase 2

Olverembatinib for FGFR1-rearranged Neoplasms

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
21