Success Metrics

Clinical Success Rate
76.8%

Based on 96 completed trials

Completion Rate
77%(96/125)
Active Trials
142(45%)
Results Posted
97%(93 trials)
Terminated
29(9%)

Phase Distribution

Ph not_applicable
2
1%
Ph phase_1
94
30%
Ph phase_4
6
2%
Ph early_phase_1
9
3%
Ph phase_2
165
53%
Ph phase_3
31
10%

Phase Distribution

103

Early Stage

165

Mid Stage

37

Late Stage

Phase Distribution307 total trials
Early Phase 1First-in-human
9(2.9%)
Phase 1Safety & dosage
94(30.6%)
Phase 2Efficacy & side effects
165(53.7%)
Phase 3Large-scale testing
31(10.1%)
Phase 4Post-market surveillance
6(2.0%)
N/ANon-phased studies
2(0.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

70.6%

96 of 136 finished

Non-Completion Rate

29.4%

40 ended early

Currently Active

142

trials recruiting

Total Trials

313

all time

Status Distribution
Active(148)
Completed(96)
Terminated(40)
Other(29)

Detailed Status

Completed96
Active, not recruiting81
Recruiting61
Terminated29
unknown28
Withdrawn11

Development Timeline

Analytics

Development Status

Total Trials
313
Active
142
Success Rate
76.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 19 (2.9%)
Phase 194 (30.6%)
Phase 2165 (53.7%)
Phase 331 (10.1%)
Phase 46 (2.0%)
N/A2 (0.7%)

Trials by Status

suspended10%
recruiting6119%
terminated299%
not_yet_recruiting52%
enrolling_by_invitation10%
unknown289%
active_not_recruiting8126%
completed9631%
withdrawn114%

Recent Activity

Clinical Trials (313)

Showing 20 of 313 trialsScroll for more
NCT06966700Phase 3

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Recruiting
NCT03486873Phase 3

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Recruiting
NCT04421963Phase 3

Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib

Active Not Recruiting
NCT02208375Phase 1

mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian

Active Not Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT04858334Phase 2

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

Recruiting
NCT07641855Phase 2

A Study of BL-B01D1 Combination Therapy in Patients With Metastatic Castration-resistant Prostate Cancer

Not Yet Recruiting
NCT03375307Phase 2

Testing Olaparib in Patients With Advanced or Metastatic (Cancer That Has Spread) Bladder Cancer and Other Genitourinary Tumors With DNA-Repair Genetic Changes

Active Not Recruiting
NCT03317392Phase 1

Testing the Safety of Different Doses of Olaparib Given Radium-223 for Men With Advanced Prostate Cancer With Bone Metastasis

Active Not Recruiting
NCT04728230Phase 1

Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial

Active Not Recruiting
NCT03737643Phase 3

Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients

Active Not Recruiting
NCT06909825Phase 2

FPI-2265 (225Ac-PSMA-I&T) and Olaparib for Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Active Not Recruiting
NCT04931342Phase 2

A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors

Active Not Recruiting
NCT04585958Phase 1

Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer

Recruiting
NCT05379972Phase 2

Study of SBRT/Olaparib Followed by Pembrolizumab/Olaparib in Gastric Cancers

Completed
NCT05887609Phase 2

An Evaluation of Maintenance Therapy Combination Mirvetuximab Soravtansine and Olaparib

Recruiting
NCT06856499Phase 1

Cirtuvivint/Olaparib in Breast Cancer Susceptibility Gene/Homologous Recombination Deficiency Platinum Resistant Ovarian Cancer

Recruiting
NCT04729387Phase 3

Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected

Terminated
NCT05554328Phase 2

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

Recruiting
NCT02446600Phase 3

Testing the Use of A Single Drug (Olaparib) or the Combination of Two Drugs (Cediranib and Olaparib) Compared to the Usual Chemotherapy for Women With Platinum Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
313