Success Metrics

Clinical Success Rate
72.7%

Based on 32 completed trials

Completion Rate
73%(32/44)
Active Trials
24(32%)
Results Posted
84%(27 trials)
Terminated
12(16%)

Phase Distribution

Ph phase_1
5
7%
Ph phase_2
6
8%
Ph phase_4
14
18%
Ph phase_3
30
39%

Phase Distribution

5

Early Stage

6

Mid Stage

44

Late Stage

Phase Distribution55 total trials
Phase 1Safety & dosage
5(9.1%)
Phase 2Efficacy & side effects
6(10.9%)
Phase 3Large-scale testing
30(54.5%)
Phase 4Post-market surveillance
14(25.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.1%

32 of 45 finished

Non-Completion Rate

28.9%

13 ended early

Currently Active

24

trials recruiting

Total Trials

76

all time

Status Distribution
Active(26)
Completed(32)
Terminated(13)
Other(5)

Detailed Status

Completed32
Active, not recruiting15
Terminated12
Recruiting9
unknown4
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
76
Active
24
Success Rate
72.7%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (9.1%)
Phase 26 (10.9%)
Phase 330 (54.5%)
Phase 414 (25.5%)

Trials by Status

active_not_recruiting1520%
terminated1216%
withdrawn11%
unknown45%
suspended11%
completed3242%
recruiting912%
enrolling_by_invitation11%
not_yet_recruiting11%

Recent Activity

Clinical Trials (76)

Showing 20 of 76 trialsScroll for more
NCT05285891Phase 4

Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

Recruiting
NCT04998812Phase 4

A Study Evaluating B Cell Levels In Infants Potentially Exposed To Ocrelizumab During Pregnancy

Completed
NCT06780150

A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS)

Recruiting
NCT04548999Phase 3

A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)

Active Not Recruiting
NCT06846281Phase 3

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

Recruiting
NCT07282574Phase 2

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis (MS)

Recruiting
NCT06495593Phase 4

Effects of Ocrelizumab Treatment on Immune Cells in Lymph Nodes in Multiple Sclerosis

Enrolling By Invitation
NCT04544449Phase 3

A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis

Active Not Recruiting
NCT07483450Phase 4

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Ocrelizumab in Participants With Relapsing Multiple Sclerosis and Primary Progressive Multiple Sclerosis

Recruiting
NCT05974852

Effect of Ocrelizumab on Choroid Plexus Changes in Patients With PPMS

Completed
NCT04035005Phase 3

A Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis

Active Not Recruiting
NCT06675955Phase 3

An Extension Study to Assess Impact of Multiple Sclerosis (MS) on Physical Function and Provide Continued Ocrelizumab Treatment

Recruiting
NCT04544436Phase 3

A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Relapsing Multiple Sclerosis (RMS)

Active Not Recruiting
NCT03593590

Non-interventional Study of Ocrelizumab in Participants With Relapsing or Primary Progressive Multiple Sclerosis

Completed
NCT07389590Phase 4

Study of Ublituximab for Ocrelizumab Wearing-Off in Multiple Sclerosis

Not Yet Recruiting
NCT04377555Phase 4

Prospective Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) After Initiation and During Treatment With Ocrelizumab

Completed
NCT04387734Phase 4

Effects of Ocrevus in Relapsing Multiple Sclerosis

Active Not Recruiting
NCT05269004Phase 3

A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis

Active Not Recruiting
NCT03523858Phase 3

A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis

Active Not Recruiting
NCT05123703Phase 3

A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis (RRMS)

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
76