Success Metrics

Clinical Success Rate

94.4%

Based on 68 completed trials

Completion Rate

94%(68/72)

Active Trials

3(3%)

Results Posted

47%(32 trials)

Terminated

4(5%)

Phase Distribution

Ph phase_2

11%

Ph phase_3

Ph phase_4

10%

Ph early_phase_1

Ph phase_1

24%

Ph not_applicable

33%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution85 total trials

Early Phase 1First-in-human

8(9.4%)

Phase 1Safety & dosage

21(24.7%)

Phase 2Efficacy & side effects

10(11.8%)

Phase 3Large-scale testing

8(9.4%)

Phase 4Post-market surveillance

9(10.6%)

N/ANon-phased studies

29(34.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

89.5%

68 of 76 finished

Non-Completion Rate

10.5%

8 ended early

Currently Active

trials recruiting

Total Trials

all time

Status Distribution

Active(4)

Completed(68)

Terminated(8)

Other(7)

Detailed Status

Completed68

Withdrawn4

unknown4

Terminated4

Suspended3

Recruiting3

Development Timeline

Analytics

Development Status

Total Trials

Active

Success Rate

94.4%

Most Advanced

Phase 4

Trials by Phase

Early Phase 18 (9.4%)

Phase 121 (24.7%)

Phase 210 (11.8%)

Phase 38 (9.4%)

Phase 49 (10.6%)

N/A29 (34.1%)

Trials by Status

not_yet_recruiting11%

completed6878%

suspended33%

withdrawn45%

unknown45%

recruiting33%

terminated45%

Recent Activity

3 active trials

Showing 5 of 87

completedphase_1

Acute Pharmacokinetic and Pharmacodynamic Effects of "Tobacco-Free" Oral Nicotine Pouches in Smokers

NCT05335915

recruitingphase_1

Clinical Trials (87)

Showing 20 of 87 trialsScroll for more

NCT05335915Phase 1

Acute Pharmacokinetic and Pharmacodynamic Effects of "Tobacco-Free" Oral Nicotine Pouches in Smokers

Completed

NCT07585006Phase 1

Comparative Evaluation of Nicotine Analogs

Recruiting

NCT06334016Early Phase 1

Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream

Not Yet Recruiting

NCT04521647Phase 1

Effects of Menthol in E-cigarettes on Smoking Behaviors

Completed

NCT06096714Early Phase 1

Addictive Threshold of Nicotine

Recruiting

NCT03652740Phase 1

Effects of Commonly Used Medications on Mood and Choice

Completed

NCT05999383Phase 2

Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration

Recruiting

NCT03635333Phase 1

Effects of E-Cigarette Flavors on Adults TCORS 2.0

Completed

NCT05278065Not Applicable

E-cigarettes for Harm Reduction in Adults With Asthma

Completed

NCT04231539Not Applicable

Pharmacokinetics, Subjective Effects, and Abuse Liability of Nicotine Salt-Based Vaping Products With Tobacco or Unflavored E-liquids, SALTVAPE Study

Completed

NCT03281694Phase 1

The Use of AVL-3288 to Potentiate the Attention-Enhancing Effects of Low-Dose Nicotine

Withdrawn

NCT00385216Phase 4

Nicotine as an Adjuvant Analgesic for Third Molar Surgery

Completed

NCT04535362Early Phase 1

Nicotine's Potential Abuse With Menthol

Completed

NCT03634839Phase 1

Effects of E-cigarette Flavors on Youth TCORS 2.0

Completed

NCT03235505Phase 4

Efficacy and Safety of E-cigarettes for Smoking Cessation in Middle-aged Heavy Smokers

Completed

NCT03091699Phase 3

Effects of Exercise and Nicotine on Cognition in Smokers

Completed

NCT04124432Phase 1

Behavioral Pharmacology of Cannabis and Nicotine

Completed

NCT06259630Phase 4

Nicotine Virtual Reality Conditioned Place Preference

Withdrawn

NCT06027723Early Phase 1

Nicotine and Pavlovian Bias

Unknown

NCT02955329Phase 3

Vaping THC From Electronic Cigarettes

Completed

Drug Details

Intervention Type: OTHER
Total Trials: 87