MK-3475
MK-3475 is a pharmaceutical drug with 29 clinical trials. Currently 4 active trials ongoing. Historical success rate of 88.0%.
Success Metrics
Based on 22 completed trials
Phase Distribution
Phase Distribution
19
Early Stage
10
Mid Stage
0
Late Stage
Highest Phase Reached
Phase 2Trial Status & Enrollment
88.0%
22 of 25 finished
12.0%
3 ended early
4
trials recruiting
29
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
A Pilot Surgical Trial To Evaluate Early Immunologic Pharmacodynamic Parameters For The PD-1 Checkpoint Inhibitor, Pembrolizumab (MK-3475), In Patients With Surgically Accessible Recurrent/Progressive Glioblastoma
MK-3475 and Gemcitabine in Non-Small Cell Lung Cancer (NSCLC)
Pembrolizumab + Imprime PGG for Metastatic Non-small Cell Lung Cancer After Progression on First-Line Therapy: Big Ten Cancer Research Consortium BTCRC-LUN15-017
A Study of Enhancing Response to MK-3475 in Advanced Colorectal Cancer
Pembrolizumab and EV With Radiation Therapy for MIBC Patients (PEVRAD)
Clinical Trials (29)
A Pilot Surgical Trial To Evaluate Early Immunologic Pharmacodynamic Parameters For The PD-1 Checkpoint Inhibitor, Pembrolizumab (MK-3475), In Patients With Surgically Accessible Recurrent/Progressive Glioblastoma
MK-3475 and Gemcitabine in Non-Small Cell Lung Cancer (NSCLC)
Pembrolizumab + Imprime PGG for Metastatic Non-small Cell Lung Cancer After Progression on First-Line Therapy: Big Ten Cancer Research Consortium BTCRC-LUN15-017
A Study of Enhancing Response to MK-3475 in Advanced Colorectal Cancer
Pembrolizumab and EV With Radiation Therapy for MIBC Patients (PEVRAD)
MK-3475 in Combination With MRI-guided Laser Ablation in Recurrent Malignant Gliomas
Radiation Therapy and MK-3475 for Patients With Recurrent/Metastatic Head and Neck Cancer, Renal Cell Cancer, Melanoma, and Lung Cancer
Study of MK-3475 (Pembrolizumab) in Patients With Microsatellite Unstable (MSI) Tumors (Cohort D)
Reirradiation With Pembrolizumab in Locoregional Inoperable Recurrence or Second Primary Squamous Cell CA of the Head and Neck
MK-3475 Immunotherapy in Endometrial Carcinoma
Evaluating the Combination of MK-3475 and Sterotactic Body Radiotherapy in Patients With Metastatic Melanoma or NSCLC
First-line CBDCA/PTX/LEN/Pembrolizumab Combination for Previously Untreated Advanced or Recurrent Thymic Carcinomas (Artemis)
Optimal Sequencing of Pembrolizumab (MK-3475) and Standard Platinum-based Chemotherapy in First-Line NSCLC
Phase Ib and Phase II Studies of MK-3475 in Combination + for Renal Cell Carcinoma:
Study of MK-3475 Alone or in Combination With Copanlisib in Relapsed or Refractory NK and T-cell Non-Hodgkin Lymphoma
Study of Pembrolizumab in Metastatic Biliary Tract Cancer as Second-line Treatment After Failing to at Least One Cytotoxic Chemotherapy Regimen: Integration of Genomic Analysis to Identify Predictive Molecular Subtypes
Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancers
A Dose Finding Study To Evaluate Safety, Drug Interaction, Tumor Markers Of Axitinib In Combination With MK-3475 In Adult Patients With Previously Untreated Advanced Renal Cell Cancer
Treatment of Advanced Melanoma With MK-3475 and Peginterferon
MK-3475 in Melanoma and NSCLC Patients With Brain Metastases
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 29