Success Metrics

Clinical Success Rate
66.7%

Based on 8 completed trials

Completion Rate
67%(8/12)
Active Trials
4(24%)
Results Posted
38%(3 trials)
Terminated
4(24%)

Phase Distribution

Ph phase_2
1
6%
Ph not_applicable
2
12%
Ph phase_1
7
41%
Ph phase_4
3
18%
Ph phase_3
3
18%
Ph early_phase_1
1
6%

Phase Distribution

8

Early Stage

1

Mid Stage

6

Late Stage

Phase Distribution17 total trials
Early Phase 1First-in-human
1(5.9%)
Phase 1Safety & dosage
7(41.2%)
Phase 2Efficacy & side effects
1(5.9%)
Phase 3Large-scale testing
3(17.6%)
Phase 4Post-market surveillance
3(17.6%)
N/ANon-phased studies
2(11.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

66.7%

8 of 12 finished

Non-Completion Rate

33.3%

4 ended early

Currently Active

4

trials recruiting

Total Trials

17

all time

Status Distribution
Active(4)
Completed(8)
Terminated(4)
Other(1)

Detailed Status

Completed8
Recruiting4
Terminated4
unknown1

Development Timeline

Analytics

Development Status

Total Trials
17
Active
4
Success Rate
66.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (5.9%)
Phase 17 (41.2%)
Phase 21 (5.9%)
Phase 33 (17.6%)
Phase 43 (17.6%)
N/A2 (11.8%)

Trials by Status

recruiting424%
completed847%
terminated424%
unknown16%

Recent Activity

4 active trials
Showing 5 of 17
recruitingphase_4

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

NCT06962306
recruitingphase_3

Methadone in TKA for Post-op Pain and Opioid Reduction

NCT07226076
recruitingphase_1

MethaLoad Dose-Finding Study

NCT06877858
completedphase_4

Perioperative Methadone Compared to Placebo in Elderly Hip Fracture Patients

NCT06086171
recruitingphase_3

Intraoperative Methadone for the Prevention of Postoperative Pain

NCT05831345
View all 17 trials

Clinical Trials (17)

Showing 17 of 17 trials
NCT06962306Phase 4

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

Recruiting
NCT07226076Phase 3

Methadone in TKA for Post-op Pain and Opioid Reduction

Recruiting
NCT06877858Phase 1

MethaLoad Dose-Finding Study

Recruiting
NCT06086171Phase 4

Perioperative Methadone Compared to Placebo in Elderly Hip Fracture Patients

Completed
NCT05831345Phase 3

Intraoperative Methadone for the Prevention of Postoperative Pain

Recruiting
NCT04680286Phase 3

Intraoperative Methadone in Children Undergoing Surgery

Terminated
NCT00930332Phase 1

Methadone Hydrochloride as First-Line Therapy in Treating Patients With Chronic Neuropathic Cancer Pain

Terminated
NCT02989597Phase 4

Intraoperative Methadone Administration for Improved Pain Control in Spinal Fusion Patients

Terminated
NCT02531906Phase 1

Gabapentin, Methadone Hydrochloride, and Oxycodone Hydrochloride in Improving Quality of Life in Patients With Stage II-IV Head and Neck Cancer During Chemoradiation

Completed
NCT00000906Phase 1

Interactions of HIV Protease Inhibitors and Methadone in HIV-Infected Patients

Completed
NCT00000800Phase 1

Methadone Effects on Zidovudine (ZDV, AZT) Disposition

Completed
NCT00000788Phase 1

A Study to Assess the Effect of Concomitant Administration of Fluconazole on the Clinical Pharmacokinetics of Methadone

Completed
NCT00726830Not Applicable

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

Terminated
NCT04112550Phase 1

Clinical Effectiveness of Pre-operative Methadone in Single Level Lateral Transpsoas Interbody Fusions

Unknown
NCT03525509Early Phase 1

Epidural Methadone in Healthy Volunteers

Completed
NCT01795495Phase 2

Methadone vs Magnesium in Spinal Fusion

Completed
NCT00001008Not Applicable

A Study of Azidothymidine Plus Methadone in Patients With AIDS and AIDS Related Complex (ARC)

Completed

All 17 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
17