MEK162
MEK162 is a pharmaceutical drug with 22 clinical trials. Currently 1 active trials ongoing. Historical success rate of 80.0%.
Success Metrics
Based on 16 completed trials
Phase Distribution
Phase Distribution
14
Early Stage
6
Mid Stage
2
Late Stage
Highest Phase Reached
Phase 3Trial Status & Enrollment
76.2%
16 of 21 finished
23.8%
5 ended early
1
trials recruiting
22
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma
MEK162 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST)
Study of MEK162 for Children With Low-Grade Gliomas
Sequential Combo Immuno and Target Therapy (SECOMBIT) Study
A Phase Ib/II Study of LGX818 in Combination With MEK162 in Adult Patients With BRAF Dependent Advanced Solid Tumors
Clinical Trials (22)
Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma
MEK162 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST)
Study of MEK162 for Children With Low-Grade Gliomas
Sequential Combo Immuno and Target Therapy (SECOMBIT) Study
A Phase Ib/II Study of LGX818 in Combination With MEK162 in Adult Patients With BRAF Dependent Advanced Solid Tumors
LGX818 and MEK162 in Combination With a Third Agent (BKM120, LEE011, BGJ398 or INC280) in Advanced BRAF Melanoma
A Phase II Study of Single Agent MEK162 in Patients With Advanced Melanoma
A Phase I/IB Trial of MEK162 in Combination With Erlotinib in NSCLC Harboring KRAS or EGFR Mutation
A Study of MEK162 (Binimetinib) in Combination With Pexidartinib in Patients With Advanced Gastrointestinal Stromal Tumor (GIST)
Study Comparing the Efficacy of MEK162 Versus Dacarbazine in Unresectable or Metastatic NRAS Mutation-positive Melanoma
MEK162 for Patients With RAS/RAF/MEK Activated Tumors
Phase Ib/II Study of Efficacy and Safety of MEK162 and Panitumumab, in Adult mCRC Patients With Mutant or Wild-type RAS Tumors
A Phase II, Open Label, Multiple Arm Study of AUY922, BYL719, INC280, LDK378 and MEK162 in Chinese Patients With Advanced Non-small Cell Lung Cancer
A Study of MEK162 and AMG 479 in Patients With Selected Solid Tumors
A Phase Ib/II Study of LEE011 in Combination With MEK162 in Patients With NRAS Mutant Melanoma
First Line Gemcitabine, Cisplatin and MEK162 in Advanced Biliary Tract Carcinoma
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MEK162 in Noonan Syndrome Hypertrophic Cardiomyopathy
A Phase I Study of Oral MEK162 in Japanese Patients With Advanced Solid Tumors
MEK162 in Healthy Subjects With Normal Hepatic Function and Subjects With Impaired Hepatic Function
A Phase Ib/II Study of AEB071 and MEK162 in Adult Patients With Metastatic Uveal Melanoma
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 22