Success Metrics

Clinical Success Rate
25.0%

Based on 5 completed trials

Completion Rate
25%(5/20)
Active Trials
1(4%)
Results Posted
380%(19 trials)
Terminated
15(54%)

Phase Distribution

Ph phase_3
3
11%
Ph phase_2
11
39%
Ph phase_1
13
46%

Phase Distribution

13

Early Stage

11

Mid Stage

3

Late Stage

Phase Distribution27 total trials
Phase 1Safety & dosage
13(48.1%)
Phase 2Efficacy & side effects
11(40.7%)
Phase 3Large-scale testing
3(11.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

19.2%

5 of 26 finished

Non-Completion Rate

80.8%

21 ended early

Currently Active

1

trials recruiting

Total Trials

28

all time

Status Distribution
Active(1)
Completed(5)
Terminated(21)
Other(1)

Detailed Status

Terminated15
Withdrawn6
Completed5
unknown1
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
28
Active
1
Success Rate
25.0%
Most Advanced
Phase 3

Trials by Phase

Phase 113 (48.1%)
Phase 211 (40.7%)
Phase 33 (11.1%)

Trials by Status

withdrawn621%
unknown14%
completed518%
active_not_recruiting14%
terminated1554%

Recent Activity

Clinical Trials (28)

Showing 20 of 28 trialsScroll for more
NCT04435691Phase 1

Magrolimab, Azacitidine, and Venetoclax for the Treatment of Acute Myeloid Leukemia

Terminated
NCT04751383Phase 1

Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma

Completed
NCT04854499Phase 2

Study of Magrolimab Combination Therapy in Patients With Head and Neck Squamous Cell Carcinoma

Terminated
NCT04958785Phase 2

Study of Magrolimab Combination Therapy in Patients With Non-Surgically Removable Locally Advanced or Metastatic Triple-Negative Breast Cancer

Terminated
NCT06046482Phase 2

Phase II Trial of Magrolimab and Cetuximab With Pembrolizumab or Docetaxel for Recurrent/Metastatic Head Neck Squamous Cell Carcinoma

Terminated
NCT04541017Phase 1

Testing the Addition of an Anti-cancer Drug, Hu5F9-G4 (Magrolimab), to the Usual Chemotherapy Treatment (Mogamulizumab) in T-Cell (a Type of Immune Cell) Lymphoma That Has Returned After Treatment or Does Not Respond to Treatment

Terminated
NCT05169944Phase 1

Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors

Completed
NCT05330429Phase 2

Study of Magrolimab Given Together With FOLFIRI/Bevacizumab (BEV) in Participants With Previously Treated Advanced Inoperable Metastatic Colorectal Cancer (mCRC)

Terminated
NCT02953509Phase 1

Trial of Magrolimab (Hu5F9-G4) in Combination With Rituximab or Rituximab + Chemotherapy in Participants With Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

Terminated
NCT04827576Phase 2

Study of Magrolimab in Patients With Solid Tumors

Terminated
NCT04892446Phase 2

Study of Magrolimab Combinations in Patients With Relapsed/Refractory Multiple Myeloma

Terminated
NCT05079230Phase 3

Study of Magrolimab Versus Placebo in Combination With Venetoclax and Azacitidine in Participants With Acute Myeloid Leukemia

Terminated
NCT04788043Phase 2

Study of Magrolimab and Pembrolizumab in Relapsed or Refractory Classic Hodgkin Lymphoma

Active Not Recruiting
NCT04778410Phase 2

Study of Magrolimab Combinations in Participants With Myeloid Malignancies

Terminated
NCT04778397Phase 3

Study of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Patients With TP53 Mutant Acute Myeloid Leukemia That Have Not Been Treated

Terminated
NCT04599634Phase 1

Venetoclax With Obinutuzumab and Magrolimab (VENOM) in Relapsed and Refractory Indolent B-cell Malignancies

Completed
NCT03248479Phase 1

Magrolimab Monotherapy or Magrolimab in Combination With Azacitidine in Participants With Hematological Malignancies

Terminated
NCT05835011Phase 2

A Study of Oral Decitabine/Cedazuridine in Combination With Magrolimab in Participants With Intermediate- to Very High-Risk Myelodysplastic Syndromes (MDS)

Terminated
NCT05823480Phase 1

Magrolimab in Combination with Azacitidine After Allogeneic HCTin Treating Patients with High-Risk AML or MDS

Withdrawn
NCT05738161Phase 1

Magrolimab in Combination With Cytotoxic Chemotherapy in Advanced Urothelial Carcinoma

Withdrawn

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
28