M7824
M7824 is a pharmaceutical drug with 22 clinical trials. Currently 6 active trials ongoing. Historical success rate of 62.5%.
Success Metrics
Based on 10 completed trials
Phase Distribution
Phase Distribution
15
Early Stage
6
Mid Stage
1
Late Stage
Highest Phase Reached
Phase 3Trial Status & Enrollment
62.5%
10 of 16 finished
37.5%
6 ended early
6
trials recruiting
22
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma
Bintrafusp Alfa (M7824) and PDS01ADC Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies
Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies
A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer
Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma
Clinical Trials (22)
PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma
Bintrafusp Alfa (M7824) and PDS01ADC Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies
Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies
A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer
Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma
HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers
Phase I/II Study of Immunotherapy Combination BN-Brachyury Vaccine, M7824, N-803 and Epacadostat (QuEST1)
Anti-PD-L1/TGF-beta Trap (M7824) Alone and in Combination With TriAd Vaccine and N-803 for Resectable Head and Neck Squamous Cell Carcinoma Not Associated With Human Papillomavirus Infection
M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers
M7824 Versus Pembrolizumab as a First-line (1L) Treatment in Participants With Programmed Death-ligand 1 (PD-L1) Expressing Advanced Non-small Cell Lung Cancer (NSCLC)
Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT)
Bintrafusp Alfa Combination Therapy in Participants With Cervical Cancer (INTR@PID 046)
M7824 With cCRT in Unresectable Stage III Non-small Cell Lung Cancer (NSCLC)
Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTC
M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer)
M7824 in Combination With Chemotherapy in Stage IV Non-small Cell Lung Cancer (NSCLC)
M7824 in Subjects With HPV Associated Malignancies
Bioimaging Study of 89Zr-M7824 in NSCLC
M7824 in People With Recurrent Respiratory Papillomatosis
Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas Cancer
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 22