Success Metrics

Clinical Success Rate

100.0%

Based on 9 completed trials

Completion Rate

100%(9/9)

Active Trials

0(0%)

Results Posted

33%(3 trials)

Phase Distribution

Ph phase_2

45%

Ph phase_4

27%

Ph phase_3

18%

Ph phase_1

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution11 total trials

Phase 1Safety & dosage

1(9.1%)

Phase 2Efficacy & side effects

5(45.5%)

Phase 3Large-scale testing

2(18.2%)

Phase 4Post-market surveillance

3(27.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

90.0%

9 of 10 finished

Non-Completion Rate

10.0%

1 ended early

Currently Active

trials recruiting

Total Trials

all time

Status Distribution

Completed(9)

Terminated(1)

Other(1)

Detailed Status

Completed9

unknown1

Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials

Active

Success Rate

100.0%

Most Advanced

Phase 4

Trials by Phase

Phase 11 (9.1%)

Phase 25 (45.5%)

Phase 32 (18.2%)

Phase 43 (27.3%)

Trials by Status

unknown19%

withdrawn19%

completed982%

Recent Activity

0 active trials

Showing 5 of 11

completedphase_2

Phase 2 Bunionectomy HTX-011 Administration Study

NCT03718039

completedphase_3

Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen

NCT03974932

completedphase_2

Clinical Trials (11)

Showing 11 of 11 trials

NCT03718039Phase 2

Phase 2 Bunionectomy HTX-011 Administration Study

Completed

NCT03974932Phase 3

Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen

Completed

NCT03695367Phase 2

Phase 2 Herniorrhaphy Study for Opioid Elimination

Completed

NCT06109415Phase 4

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE.

Completed

NCT06109428Phase 4

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE

Completed

NCT05109312Phase 4

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.

Unknown

NCT04911062Phase 2

HTX-011 in Spinal Surgery

Completed

NCT03922048Phase 2

Pediatric Postoperative Analgesia Herniorrhaphy Study

Withdrawn

NCT03955211Phase 2

HTX-011 Administration Study in Planned Caesarean Section Procedure

Completed

NCT03907176Phase 3

Herniorrhaphy Study for Opioid Elimination

Completed

NCT04398329Phase 1

Dose-Escalation Study of HTX-034 Following Bunionectomy

Completed

All 11 trials loaded

Drug Details

Intervention Type: DEVICE
Total Trials: 11