Success Metrics

Clinical Success Rate
75.0%

Based on 3 completed trials

Completion Rate
75%(3/4)
Active Trials
15(58%)
Results Posted
100%(3 trials)
Terminated
1(4%)

Phase Distribution

Ph not_applicable
1
4%
Ph phase_2
15
58%
Ph phase_3
4
15%
Ph phase_1
6
23%

Phase Distribution

6

Early Stage

15

Mid Stage

4

Late Stage

Phase Distribution26 total trials
Phase 1Safety & dosage
6(23.1%)
Phase 2Efficacy & side effects
15(57.7%)
Phase 3Large-scale testing
4(15.4%)
N/ANon-phased studies
1(3.8%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

3 of 6 finished

Non-Completion Rate

50.0%

3 ended early

Currently Active

15

trials recruiting

Total Trials

26

all time

Status Distribution
Active(20)
Completed(3)
Terminated(3)

Detailed Status

Recruiting11
Not yet recruiting5
Active, not recruiting4
Completed3
Withdrawn2
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
26
Active
15
Success Rate
75.0%
Most Advanced
Phase 3

Trials by Phase

Phase 16 (23.1%)
Phase 215 (57.7%)
Phase 34 (15.4%)
N/A1 (3.8%)

Trials by Status

recruiting1142%
withdrawn28%
terminated14%
completed312%
active_not_recruiting415%
not_yet_recruiting519%

Recent Activity

Clinical Trials (26)

Showing 20 of 26 trialsScroll for more
NCT07076212Phase 2

Evaluating NALIRIFOX vs Modified Gemcitabine, Nab-Paclitaxel and Cisplatin in Patients With Locally Advanced and Metastatic Pancreatic Adenocarcinoma

Recruiting
NCT07570914Phase 2

Hepatic Arterial Infusion of Liposomal Irinotecan Plus Oxaliplatin and Capecitabine as Adjuvant Therapy for Colorectal Cancer Liver Metastases

Not Yet Recruiting
NCT04233866Phase 2

Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread

Active Not Recruiting
NCT06625320Phase 3

Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

Active Not Recruiting
NCT07409272Phase 3

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

Recruiting
NCT05382559Phase 1

A Study of ASP3082 in Adults With Advanced Solid Tumors

Recruiting
NCT05854498Phase 2

Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal Cancer

Recruiting
NCT07479732Phase 1

Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma

Recruiting
NCT07474103Not Applicable

SCRT-NALIRIXELOX+Sintilimab as TNT for High-Risk LARC

Recruiting
NCT03483038Phase 2

A Study of the Safety and Activity of Liposomal Irinotecan in Combination With the 5-FU and Oxaliplatin in the Preoperative Treatment of Pancreatic Adenocarcinoma

Active Not Recruiting
NCT06023641Phase 2

Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

Recruiting
NCT07104604Phase 1

Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Toripalimab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement

Recruiting
NCT03764553Phase 2

Liposomal iRInotecan, Carboplatin or oXaliplatin for Esophagogastric Cancer

Active Not Recruiting
NCT03861702Phase 2

Liposomal Irinotecan in Combination With Oxaliplatin, Leucovorin, and 5-fluorouracil for Patients With Locally Advanced Pancreatic Carcinoma:

Completed
NCT06210971Phase 2

Neoadjuvant Chemoradiation With Nal-IRI and Capecitabine Guided by UGT1A1 Status in Patients With Rectal Cancer

Recruiting
NCT03736720Phase 2

Liposomal Irinotecan, Fluorouracil and Leucovorin in Treating Patients With Refractory Advanced High Grade Neuroendocrine Cancer of Gastrointestinal, Unknown, or Pancreatic Origin

Terminated
NCT03837977Phase 2

Second-line Therapy for Patients With Progressive Poorly Differentiated Extra-pulmonary Neuroendocrine Carcinoma

Completed
NCT06184698Phase 2

Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal Cancer

Recruiting
NCT06571461Phase 3

Liposomal Irinotecan in Combination With Oxaliplatin and S-1 Versus Gemcitabine Combined With Capecitabine as Postoperative Adjuvant Therapy for Pancreatic Cancer

Not Yet Recruiting
NCT06501664Phase 3

Liposomal Irinotecan and 5-FU as Second-line Therapy for Patients With ESCC

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
26