Success Metrics

Clinical Success Rate

78.0%

Based on 71 completed trials

Completion Rate

78%(71/91)

Active Trials

19(13%)

Results Posted

87%(62 trials)

Terminated

20(14%)

Phase Distribution

Ph phase_2

12%

Ph phase_4

54%

Ph early_phase_1

Ph not_applicable

Ph phase_1

Ph phase_3

19%

Phase Distribution

Early Stage

Mid Stage

106

Late Stage

Phase Distribution141 total trials

Early Phase 1First-in-human

3(2.1%)

Phase 1Safety & dosage

5(3.5%)

Phase 2Efficacy & side effects

17(12.1%)

Phase 3Large-scale testing

27(19.1%)

Phase 4Post-market surveillance

79(56.0%)

N/ANon-phased studies

10(7.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

70.3%

71 of 101 finished

Non-Completion Rate

29.7%

30 ended early

Currently Active

trials recruiting

Total Trials

145

all time

Status Distribution

Active(25)

Completed(71)

Terminated(30)

Other(19)

Detailed Status

Completed71

Terminated20

unknown18

Recruiting13

Withdrawn10

Active, not recruiting6

Development Timeline

Analytics

Development Status

Total Trials

145

Active

Success Rate

78.0%

Most Advanced

Phase 4

Trials by Phase

Early Phase 13 (2.1%)

Phase 15 (3.5%)

Phase 217 (12.1%)

Phase 327 (19.1%)

Phase 479 (56.0%)

N/A10 (7.1%)

Trials by Status

unknown1812%

completed7149%

active_not_recruiting64%

not_yet_recruiting43%

recruiting139%

terminated2014%

withdrawn107%

enrolling_by_invitation21%

suspended11%

Recent Activity

19 active trials

Showing 5 of 145

not_yet_recruitingphase_4

A Study Of Stellate Ganglion Blockade With Liposomal Bupivacaine In Preventing Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting Surgery

NCT07570940

completedphase_2

Video-assisted Thoracoscopic Surgery - Exparel Study

NCT04864210

terminatedphase_4

Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients

NCT05900427

not_yet_recruitingphase_4

Liposomal Bupivacaine vs Perineural Adjuvants in Adductor Canalf and iPACK Blocks in Total Knee Arthroplasty

NCT07097493

active_not_recruitingphase_2

Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)

NCT04189783

View all 145 trials

Clinical Trials (145)

Showing 20 of 145 trialsScroll for more

NCT07570940Phase 4

A Study Of Stellate Ganglion Blockade With Liposomal Bupivacaine In Preventing Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting Surgery

Not Yet Recruiting

NCT04864210Phase 2

Video-assisted Thoracoscopic Surgery - Exparel Study

Completed

NCT05900427Phase 4

Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients

Terminated

NCT07097493Phase 4

Liposomal Bupivacaine vs Perineural Adjuvants in Adductor Canalf and iPACK Blocks in Total Knee Arthroplasty

Not Yet Recruiting

NCT04189783Phase 2

Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)

Active Not Recruiting

NCT03854344Phase 4

Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain

Completed

NCT05044468Phase 2

EXPAREL or Lidocane as Local Anesthetic in Patients Undergoing Pleuroscopy With Pleural Biopsy and Indwelling Pleural Catheter Placement

Active Not Recruiting

NCT03214510Phase 3

Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery

Active Not Recruiting

NCT07271979Not Applicable

Liposomal Bupivacaine Versus Ropivacaine for Preperitoneal Infiltration Analgesia in Upper Abdominal Laparotomy

Recruiting

NCT04333095Phase 4

Sternal Block With Liposomal Bupivacaine vs. Saline Prior to Incision in Cardiac Surgery

Completed

NCT06411795Phase 2

Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy

Recruiting

NCT06575699Phase 4

Rectus Sheath Block for Analgesia After Gynecological Laparotomy

Completed

NCT05140499Phase 4

Liposomal Bupivacaine vs Continuous Nerve Catheters for Below the Knee Amputations

Terminated

NCT05891613Phase 4

A Study of Liposomal Bupivacaine Versus 0.25% Bupivacaine Hydrochloride Post Breast Reduction

Completed

NCT03599635Phase 4

Pec Infiltration With Liposomal Bupivacaine for Breast Surgery

Completed

NCT07222748Phase 3

A Study of TLC590 for Postsurgical Pain Following Bunionectomy

Recruiting

NCT06179004Phase 3

Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery

Recruiting

NCT05795413

Quality of Recovery From Mastectomy With and Without PECS Blocks

Active Not Recruiting

NCT05177991Early Phase 1

Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs

Active Not Recruiting

NCT05862792

Liposomal Bupivacaine and Transoral Robotic Surgery

Recruiting

Drug Details

Intervention Type: DRUG
Total Trials: 145