Success Metrics

Clinical Success Rate

78.5%

Based on 73 completed trials

Completion Rate

78%(73/93)

Active Trials

19(13%)

Results Posted

89%(65 trials)

Terminated

20(14%)

Phase Distribution

Ph not_applicable

Ph phase_1

Ph early_phase_1

Ph phase_2

12%

Ph phase_3

18%

Ph phase_4

54%

Phase Distribution

Early Stage

Mid Stage

107

Late Stage

Phase Distribution144 total trials

Early Phase 1First-in-human

3(2.1%)

Phase 1Safety & dosage

5(3.5%)

Phase 2Efficacy & side effects

18(12.5%)

Phase 3Large-scale testing

27(18.8%)

Phase 4Post-market surveillance

80(55.6%)

N/ANon-phased studies

11(7.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

70.9%

73 of 103 finished

Non-Completion Rate

29.1%

30 ended early

Currently Active

trials recruiting

Total Trials

148

all time

Status Distribution

Active(27)

Completed(73)

Terminated(30)

Other(18)

Detailed Status

Completed73

Terminated20

unknown17

Recruiting12

Withdrawn10

Active, not recruiting7

Development Timeline

Analytics

Development Status

Total Trials

148

Active

Success Rate

78.5%

Most Advanced

Phase 4

Trials by Phase

Early Phase 13 (2.1%)

Phase 15 (3.5%)

Phase 218 (12.5%)

Phase 327 (18.8%)

Phase 480 (55.6%)

N/A11 (7.6%)

Trials by Status

withdrawn107%

unknown1711%

suspended11%

terminated2014%

completed7349%

active_not_recruiting75%

enrolling_by_invitation32%

not_yet_recruiting53%

recruiting128%

Recent Activity

19 active trials

Showing 5 of 148

not_yet_recruitingphase_4

A Study Of Stellate Ganglion Blockade With Liposomal Bupivacaine In Preventing Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting Surgery

NCT07570940

not_yet_recruitingphase_4

Effect of Liposomal Bupivacaine on Rebound Pain After Peripheral Nerve Block in Orthopedic Surgery.

NCT07606911

not_yet_recruitingphase_4

Liposomal Bupivacaine vs Perineural Adjuvants in Adductor Canalf and iPACK Blocks in Total Knee Arthroplasty

NCT07097493

recruitingphase_2

Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia

NCT07689162

terminatedphase_4

Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients

NCT05900427

View all 148 trials

Clinical Trials (148)

Showing 20 of 148 trialsScroll for more

NCT07570940Phase 4

A Study Of Stellate Ganglion Blockade With Liposomal Bupivacaine In Preventing Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting Surgery

Not Yet Recruiting

NCT07606911Phase 4

Effect of Liposomal Bupivacaine on Rebound Pain After Peripheral Nerve Block in Orthopedic Surgery.

Not Yet Recruiting

NCT07097493Phase 4

Liposomal Bupivacaine vs Perineural Adjuvants in Adductor Canalf and iPACK Blocks in Total Knee Arthroplasty

Not Yet Recruiting

NCT07689162Phase 2

Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia

Recruiting

NCT05900427Phase 4

Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients

Terminated

NCT07271979Not Applicable

Liposomal Bupivacaine Versus Ropivacaine for Preperitoneal Infiltration Analgesia in Upper Abdominal Laparotomy

Completed

NCT03214510Phase 3

Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery

Active Not Recruiting

NCT07222748Phase 3

A Study of TLC590 for Postsurgical Pain Following Bunionectomy

Active Not Recruiting

NCT07587203Not Applicable

Effect of Liposomal Bupivacaine and Bupivacaine Hydrochloride for Superior Trunk Block of the Interscalene Brachial Plexus on Postoperative Diaphragmatic Function and Analgesia

Enrolling By Invitation

NCT05374499Phase 4

Double-Blinded Randomized Controlled Study Investigating the Efficacy of Exparel (Liposomal Bupivacaine) for Postoperative Pain Relief in Mandibular Third Molar Extractions

Completed

NCT04117074Phase 3

Thoracic Epidural Analgesia vs Surgical Site Infiltration With Liposomal Bupivacaine Following Open Gynecologic Surgery

Completed

NCT04928664Phase 4

Continuous vs Liposomal Bupivacaine Interscalene Block for Proximal Humeral Fracture (CLIP)

Completed

NCT04864210Phase 2

Video-assisted Thoracoscopic Surgery - Exparel Study

Completed

NCT04189783Phase 2

Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)

Active Not Recruiting

NCT03854344Phase 4

Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain

Completed

NCT05044468Phase 2

EXPAREL or Lidocane as Local Anesthetic in Patients Undergoing Pleuroscopy With Pleural Biopsy and Indwelling Pleural Catheter Placement

Active Not Recruiting

NCT04333095Phase 4

Sternal Block With Liposomal Bupivacaine vs. Saline Prior to Incision in Cardiac Surgery

Completed

NCT06411795Phase 2

Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy

Recruiting

NCT06575699Phase 4

Rectus Sheath Block for Analgesia After Gynecological Laparotomy

Completed

NCT05140499Phase 4

Liposomal Bupivacaine vs Continuous Nerve Catheters for Below the Knee Amputations

Terminated

Drug Details

Intervention Type: DRUG
Total Trials: 148