Success Metrics

Clinical Success Rate
80.9%

Based on 38 completed trials

Completion Rate
81%(38/47)
Active Trials
2(3%)
Results Posted
24%(9 trials)
Terminated
9(11%)

Phase Distribution

Ph phase_1
1
1%
Ph phase_2
20
25%
Ph phase_4
26
33%
Ph phase_3
16
20%
Ph not_applicable
7
9%

Phase Distribution

1

Early Stage

20

Mid Stage

42

Late Stage

Phase Distribution70 total trials
Phase 1Safety & dosage
1(1.4%)
Phase 2Efficacy & side effects
20(28.6%)
Phase 3Large-scale testing
16(22.9%)
Phase 4Post-market surveillance
26(37.1%)
N/ANon-phased studies
7(10.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

77.6%

38 of 49 finished

Non-Completion Rate

22.4%

11 ended early

Currently Active

2

trials recruiting

Total Trials

79

all time

Status Distribution
Active(3)
Completed(38)
Terminated(11)
Other(27)

Detailed Status

Completed38
unknown27
Terminated9
Withdrawn2
Recruiting2
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
79
Active
2
Success Rate
80.9%
Most Advanced
Phase 4

Trials by Phase

Phase 11 (1.4%)
Phase 220 (28.6%)
Phase 316 (22.9%)
Phase 426 (37.1%)
N/A7 (10.0%)

Trials by Status

withdrawn23%
not_yet_recruiting11%
completed3848%
terminated911%
unknown2734%
recruiting23%

Recent Activity

Clinical Trials (79)

Showing 20 of 79 trialsScroll for more
NCT03624010Phase 2

Open-Label Rollover Study of Levosimendan in PH-HFpEF Patients

Completed
NCT04158674Phase 3

Interest of Levosimendan in Reducing Weaning Failures of ExtraCorporeal Life Support - ECLS

Terminated
NCT07105202Phase 4

Shorter Weaning From Invasive Ventilation With Levosimendan

Recruiting
NCT07262723Phase 2

Levosimendan in Acute Decompensated Heart Failure

Not Yet Recruiting
NCT07186062

Clinical Outcomes of Levosimendan Versus Dobutamine Versus Milrinone in Cases With Acute Decompensated Heart Failure With Impaired Renal Function

Completed
NCT05664191Phase 2

Levosimendan as Treatment of Aneurysmal SubArachnoid Haemorrhage

Recruiting
NCT04705337Phase 4

Levosimendan In Ambulatory Heart Failure Patients

Terminated
NCT04329624Phase 3

Effect Levosimendan Administration on Postoperative NT-proBNP in Cardiac Risk Patients

Completed
NCT04728932Phase 3

LEVOSIMENDAN to Facilitate Weaning From ECMO in Severe Cardiogenic Shock Patients

Completed
NCT03541603Phase 2

Hemodynamic Evaluation of Levosimendan in Patients With PH-HFpEF

Completed
NCT02232399Phase 2

Is Levosimendan Superior to Milrinone Regarding Acute Kidney Injury After Cardiac Surgery for Congenital Heart Disease?

Completed
NCT04330755Phase 4

Levosimendan Versus Combination With Magnesium Sulphate on Spine Protection by NIRS in Infants Undergoing Coarctectomy

Completed
NCT06021587

Interest of Levosimendan Preconditioning for Cardiac Surgery Under CEC in Heart Failure Patients With Impaired Ejection Fraction

Unknown
NCT05233202Phase 3

Levosimendan Versus Placebo Before Tricuspid Valve Surgery in Patients With Right Ventricular Dysfunction

Unknown
NCT05768230Phase 2

Using TEE to Evaluate the Effect of Levosimendan on Patients With ARDS Associated With RVD During MV

Unknown
NCT03948178Phase 3

Effects of Oral Levosimendan on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis (ALS): Open-Label Extension

Terminated
NCT05730907

Efficacy and Clinical Outcomes of Levosimendan in E-CPR

Unknown
NCT05685537

Impact of Levosimendan Preconditioning on Critical Care and In-hospital Lengths of Stay After Cardiac Surgery With Bypass Surgery

Unknown
NCT03022877Not Applicable

Acute and Chronic Protective Effects of Peri-interventional Administration of Levosimendan in ST Elevation Myocardial Infarctions

Withdrawn
NCT03505021Phase 3

Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS

Completed

Drug Details

Intervention Type
DRUG
Total Trials
79