Success Metrics

Clinical Success Rate
81.3%

Based on 209 completed trials

Completion Rate
81%(209/257)
Active Trials
101(23%)
Results Posted
67%(141 trials)
Terminated
48(11%)

Phase Distribution

Ph phase_2
176
41%
Ph phase_3
95
22%
Ph phase_4
36
8%
Ph early_phase_1
12
3%
Ph phase_1
58
13%
Ph not_applicable
39
9%

Phase Distribution

70

Early Stage

176

Mid Stage

131

Late Stage

Phase Distribution416 total trials
Early Phase 1First-in-human
12(2.9%)
Phase 1Safety & dosage
58(13.9%)
Phase 2Efficacy & side effects
176(42.3%)
Phase 3Large-scale testing
95(22.8%)
Phase 4Post-market surveillance
36(8.7%)
N/ANon-phased studies
39(9.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.8%

209 of 272 finished

Non-Completion Rate

23.2%

63 ended early

Currently Active

101

trials recruiting

Total Trials

431

all time

Status Distribution
Active(109)
Completed(209)
Terminated(63)
Other(50)

Detailed Status

Completed209
Recruiting57
unknown49
Terminated48
Active, not recruiting44
Withdrawn15

Development Timeline

Analytics

Development Status

Total Trials
431
Active
101
Success Rate
81.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 112 (2.9%)
Phase 158 (13.9%)
Phase 2176 (42.3%)
Phase 395 (22.8%)
Phase 436 (8.7%)
N/A39 (9.4%)

Trials by Status

completed20948%
terminated4811%
enrolling_by_invitation10%
recruiting5713%
unknown4911%
withdrawn153%
not_yet_recruiting72%
active_not_recruiting4410%
suspended10%

Recent Activity

Clinical Trials (431)

Showing 20 of 431 trialsScroll for more
NCT06072781Phase 3

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

Recruiting
NCT01272037Phase 3

Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer

Active Not Recruiting
NCT00310180Phase 3

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Active Not Recruiting
NCT01797523Phase 2

A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma

Completed
NCT05649956Phase 2

Letrozole in Uterine Leiomyosarcoma

Recruiting
NCT07174336Phase 3

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Recruiting
NCT07288359Phase 1

Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

Recruiting
NCT06380751Phase 3

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Recruiting
NCT06998407Phase 1

ORION-1: Study of AVZO-023 as a Single Agent and in Combination With AVZO-021, and/or Endocrine Therapy in Advanced Solid Tumors

Recruiting
NCT07492641Phase 3

BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease

Recruiting
NCT06120283Phase 1

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

Recruiting
NCT07391774Phase 3

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

Recruiting
NCT06075953Phase 2

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

Recruiting
NCT07716046Phase 2

Fulvestaciclib Combined With Anti-HER2 and Endocrine Therapy for HR+/HER2+ Advanced Breast Cancer

Not Yet Recruiting
NCT05774951Phase 3

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Recruiting
NCT06394804Phase 2

A Study of Avutometinib, Defactinib, and Letrozole in People With Low-Grade Serous Ovarian Cancer

Recruiting
NCT05464810Early Phase 1

Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer

Recruiting
NCT07085767Phase 3

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

Recruiting
NCT05827081Phase 3

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

Recruiting
NCT04469764Phase 2

Abemaciclib for the Treatment of Recurrent Ovarian or Endometrial Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
431