Success Metrics

Clinical Success Rate
81.6%

Based on 213 completed trials

Completion Rate
82%(213/261)
Active Trials
98(23%)
Results Posted
67%(142 trials)
Terminated
48(11%)

Phase Distribution

Ph phase_2
178
41%
Ph phase_4
36
8%
Ph phase_1
58
13%
Ph phase_3
95
22%
Ph not_applicable
39
9%
Ph early_phase_1
12
3%

Phase Distribution

70

Early Stage

178

Mid Stage

131

Late Stage

Phase Distribution418 total trials
Early Phase 1First-in-human
12(2.9%)
Phase 1Safety & dosage
58(13.9%)
Phase 2Efficacy & side effects
178(42.6%)
Phase 3Large-scale testing
95(22.7%)
Phase 4Post-market surveillance
36(8.6%)
N/ANon-phased studies
39(9.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

77.2%

213 of 276 finished

Non-Completion Rate

22.8%

63 ended early

Currently Active

98

trials recruiting

Total Trials

433

all time

Status Distribution
Active(107)
Completed(213)
Terminated(63)
Other(50)

Detailed Status

Completed213
Recruiting52
unknown49
Terminated48
Active, not recruiting46
Withdrawn15

Development Timeline

Analytics

Development Status

Total Trials
433
Active
98
Success Rate
81.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 112 (2.9%)
Phase 158 (13.9%)
Phase 2178 (42.6%)
Phase 395 (22.7%)
Phase 436 (8.6%)
N/A39 (9.3%)

Trials by Status

active_not_recruiting4611%
suspended10%
enrolling_by_invitation10%
recruiting5212%
terminated4811%
withdrawn153%
completed21349%
unknown4911%
not_yet_recruiting82%

Recent Activity

Clinical Trials (433)

Showing 20 of 433 trialsScroll for more
NCT07391774Phase 3

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

Recruiting
NCT05827081Phase 3

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

Recruiting
NCT00310180Phase 3

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Active Not Recruiting
NCT05161195Phase 4

Roll-over Study to Allow Continued Access to Ribociclib

Active Not Recruiting
NCT01272037Phase 3

Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer

Active Not Recruiting
NCT03283384Phase 2

Tailoring NEOadjuvant Therapy in Hormone Receptor Positive, HER2 Negative, Luminal Breast Cancer.

Active Not Recruiting
NCT07492641Phase 3

BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease

Recruiting
NCT06120283Phase 1

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

Recruiting
NCT06075953Phase 2

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

Recruiting
NCT05867251Phase 1

Study of AVZO-021 in Patients With Advanced Solid Tumors

Recruiting
NCT02188745Phase 2

ER Reactivation Therapy for Breast Cancer

Completed
NCT06979596Phase 2

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

Recruiting
NCT07842796Phase 2

Sequential vs. Combined Letrozole and Methotrexate for Tubal Ectopic Pregnancy.

Active Not Recruiting
NCT07054190Phase 2

A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer

Recruiting
NCT06179303Phase 2

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

Recruiting
NCT07085767Phase 3

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

Recruiting
NCT04964934Phase 3

Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)

Active Not Recruiting
NCT07174336Phase 3

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Recruiting
NCT07679269Phase 2

Roll-Over Study of Alpelisib (BYL719) for Continued Access and Long-Term Safety.

Not Yet Recruiting
NCT01872260Phase 1

Study of LEE011, BYL719 and Letrozole in Advanced ER+ Breast Cancer

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
433