Success Metrics

Clinical Success Rate
94.7%

Based on 36 completed trials

Completion Rate
95%(36/38)
Active Trials
0(0%)
Results Posted
100%(36 trials)
Terminated
2(5%)

Phase Distribution

Ph phase_2
23
61%
Ph phase_4
1
3%
Ph phase_3
12
32%

Phase Distribution

0

Early Stage

23

Mid Stage

13

Late Stage

Phase Distribution36 total trials
Phase 2Efficacy & side effects
23(63.9%)
Phase 3Large-scale testing
12(33.3%)
Phase 4Post-market surveillance
1(2.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

94.7%

36 of 38 finished

Non-Completion Rate

5.3%

2 ended early

Currently Active

0

trials recruiting

Total Trials

38

all time

Status Distribution
Completed(36)
Terminated(2)

Detailed Status

Completed36
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
38
Active
0
Success Rate
94.7%
Most Advanced
Phase 4

Trials by Phase

Phase 223 (63.9%)
Phase 312 (33.3%)
Phase 41 (2.8%)

Trials by Status

completed3695%
terminated25%

Recent Activity

Clinical Trials (38)

Showing 20 of 38 trialsScroll for more
NCT02292706

A Registry for Participants With Cirrhosis Who Achieve a Sustained Virologic Response Following Treatment With a Sofosbuvir-Based Regimen Without Interferon for Chronic Hepatitis C Infection

Terminated
NCT02951364

Harvoni in Patients With Chronic Hepatitis C Virus (HCV) Infection in Korea

Completed
NCT02613871Phase 3

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination in Adults With Chronic HCV and HBV Coinfection

Completed
NCT02021656Phase 3

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination in Participants With Chronic Genotype 1 HCV Infection

Completed
NCT03036839Phase 2

Ledipasvir/Sofosbuvir in Adults With Chronic Hepatitis C Virus (HCV) Infection Who Are on Dialysis for End Stage Renal Disease

Completed
NCT02868242Phase 2

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed Dose Combination in the Treatment of Hepatitis C Virus (HCV) Infection in Pediatric Participants Undergoing Cancer Chemotherapy

Completed
NCT02249182Phase 2

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination +/- Ribavirin in Adolescents and Children With Chronic HCV-Infection

Completed
NCT01984294Phase 2

Ledipasvir/Sofosbuvir Fixed-Dose Combination With Ribavirin or GS-9669 in Subjects With Chronic Genotype 1 HCV Infection

Completed
NCT02251717Phase 2

Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed Dose Combination (FDC) for 12 or 24 Weeks in Kidney Transplant Recipients With Chronic HCV Infection

Completed
NCT02301936Phase 2

Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 or 24 Weeks in Genotype 1 or 4 HCV Infected Adults With Sickle Cell Disease

Completed
NCT01924949Phase 2

Ledipasvir/Sofosbuvir Fixed-Dose Combination in Adults With Nosocomial Genotype 1 HCV Infection

Completed
NCT02350569Phase 2

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination Administered in Patients Infected With Chronic Genotype 1 or 4 HCV for Use in the Peri-Operative Liver Transplantation Setting

Completed
NCT02081079Phase 2

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination in Treatment-Naive and Treatment-Experienced Subjects With Chronic Genotype 4 or 5 HCV Infection

Completed
NCT02010255Phase 2

Ledipasvir/Sofosbuvir Fixed-Dose Combination Plus Ribavirin in Participants With Chronic HCV With Advanced Liver Disease or Post-Liver Transplant

Completed
NCT01987453Phase 2

Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin in Participants With Chronic Genotype 1 HCV Who Participated in a Prior Gilead-Sponsored HCV Treatment Study

Completed
NCT01701401Phase 3

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination (FDC) With and Without Ribavirin for the Treatment of HCV

Completed
NCT01975675Phase 3

Efficacy and Safety of Sofosbuvir/Ledipasvir ± Ribavirin in Japanese Participants With Chronic Genotype 1 HCV Infection

Completed
NCT02472886Phase 3

Safety and Efficacy of Ledipasvir/Sofosbuvir in Adults With Chronic HCV Infection

Completed
NCT02413593Phase 2

Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed Dose Combination Tablet With Ribavirin for 12 Weeks in Treatment-naive Adults With Chronic HCV Genotype 3 Infection

Completed
NCT02202980Phase 2

Efficacy and Safety of Oral Regimens for the Treatment of Chronic HCV Infection

Completed

Drug Details

Intervention Type
DRUG
Total Trials
38