L-Citrulline
L-Citrulline is a dietary supplement with 39 clinical trials. Currently 6 active trials ongoing. Historical success rate of 84.6%.
Success Metrics
Based on 22 completed trials
Phase Distribution
Phase Distribution
9
Early Stage
3
Mid Stage
5
Late Stage
Highest Phase Reached
Phase 3Trial Status & Enrollment
84.6%
22 of 26 finished
15.4%
4 ended early
6
trials recruiting
39
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Safety and PK-PD Study of Oral L-CIT in Preterm Infants With BPD±PH and NEC
Novel Approaches for Improving Vascular Function in Veterans With HFpEF
Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease
L-citrulline to Improve Adverse Outcomes in Admitted Children (EChiLiBRiST, Clinical Trial 2, Inpatients)
Role of L-citrulline in Prevention of Pregnancy Associated Hypertension
Clinical Trials (39)
Safety and PK-PD Study of Oral L-CIT in Preterm Infants With BPD±PH and NEC
Novel Approaches for Improving Vascular Function in Veterans With HFpEF
Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease
L-citrulline to Improve Adverse Outcomes in Admitted Children (EChiLiBRiST, Clinical Trial 2, Inpatients)
Role of L-citrulline in Prevention of Pregnancy Associated Hypertension
L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE)
A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis
The Effect of 4 Weeks of L-Citrulline Supplementation on Macro- and Microvascular Function in Type 2 Diabetes
2 Weeks of Citrulline Supplementation on Arterial Function in Postmenopausal Women With Elevated Blood Pressure or Hypertension
Effect of L-citrulline and HIIT on Arterial Stiffness, Body Composition, and Lipid Profile in Adolescents with Steatosis Associated with Metabolic Dysfunction (MASLD)
L-citrulline Injection in Patients Aged 6-21 Years Old with Sickle Cell Disease Presenting with Vaso-Occlusive Crisis (VOC)
A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects
L-Citrulline Dose Finding Safety Study in MELAS
L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia
Oral Citrulline Supplementation in COPD Patients With Malnutrition
The Effect of Short-term L-citrulline Supplementation on Blood Pressure and Arterial Stiffness
Study to Improve Deployment Related Asthma by Using L-Citrulline Supplementation
L-citrulline for Prevention of Sequelae of Acute Lung Injury in Pediatrics Undergoing Cardiopulmonary Bypass for Heart Defects
Intravenous L-Citrulline Influence on the Need for Invasive Mechanical Ventilation for Acute Hypoxemic Respiratory Failure in Patients With COVID-19
Effects of L-Citrulline or Citrulline-malate on Neuromuscular Performance in Resistance-trained Adults
Drug Details
- Intervention Type
- DIETARY SUPPLEMENT
- Total Trials
- 39