Success Metrics

Clinical Success Rate
66.7%

Based on 20 completed trials

Completion Rate
67%(20/30)
Active Trials
0(0%)
Results Posted
75%(15 trials)
Terminated
10(31%)

Phase Distribution

Ph phase_1
19
59%
Ph phase_2
13
41%

Phase Distribution

19

Early Stage

13

Mid Stage

0

Late Stage

Phase Distribution32 total trials
Phase 1Safety & dosage
19(59.4%)
Phase 2Efficacy & side effects
13(40.6%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

64.5%

20 of 31 finished

Non-Completion Rate

35.5%

11 ended early

Currently Active

0

trials recruiting

Total Trials

32

all time

Status Distribution
Completed(20)
Terminated(11)
Other(1)

Detailed Status

Completed20
Terminated10
unknown1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
32
Active
0
Success Rate
66.7%
Most Advanced
Phase 2

Trials by Phase

Phase 119 (59.4%)
Phase 213 (40.6%)

Trials by Status

completed2063%
terminated1031%
unknown13%
withdrawn13%

Recent Activity

Clinical Trials (32)

Showing 20 of 32 trialsScroll for more
NCT02717455Phase 1

Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma

Completed
NCT01238692Phase 2

A Phase II Study of Oral Panobinostat (LBH589) and Rituximab to Treat Diffuse Large B Cell Lymphoma (DLBCL)

Completed
NCT00550277Phase 2

LBH589 Treatment for Refractory Clear Cell Renal Carcinoma

Completed
NCT00449761Phase 2

Efficacy and Safety of LBH589B in Adult Patients With Refractory Chronic Myeloid Leukemia in Accelerated or Blast Phase

Terminated
NCT00451035Phase 2

Efficacy and Safety of LBH589 in Adult Patients With Refractory Chronic Myeloid Leukemia (CML) in Chronic Phase

Terminated
NCT00445068Phase 2

Efficacy and Safety of LBH589B in Adult Patients With Multiple Myeloma

Terminated
NCT00936611Phase 2

LBH589 in Relapsed or Relapsed and Refractory Waldenstrom's Macroglobulinemia

Completed
NCT00621244Phase 1

A Study of Oral LBH589 in Adult Patients With Advanced Hematological Malignancies

Completed
NCT00503451Phase 1

A Study to Investigate the Effects of Ketoconazole on LBH589 in Patients With Advanced Solid Tumors

Completed
NCT00535951Phase 1

Pharmacokinetic, Safety, and Efficacy Effects of Oral LBH589 on Dextromethorphan in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer or Malignant Pleural Mesothelioma

Completed
NCT00739414Phase 1

Dose-escalating Study of LBH589 in Adult Patients With Advanced Solid Tumors

Completed
NCT01007968Phase 1

Pharmacokinetics and Safety of Panobinostat in Patients With Advanced Solid Tumors and Various Degrees of Hepatic Function

Completed
NCT00532389Phase 1

Safety Study of LBH589 When Given in Combination With Bortezomib in Adult Patients With Multiple Myeloma

Completed
NCT00570284Phase 1

A Study to Investigate the Effect of Food on Oral LBH589 Absorption in Patients With Advanced Solid Tumors

Completed
NCT00532675Phase 1

Safety Study of LBH589 When Given in Combination With Lenalidomide and Dexamethasone in Adult Patients With Multiple Myeloma.

Completed
NCT00493766Phase 1

Safety of LBH589 Alone and in Combination With IV Docetaxel and Prednisone

Terminated
NCT01013597Phase 2

Trial of LBH589 in Metastatic Thyroid Cancer

Completed
NCT00939159Phase 2

Study of LBH589 for Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)

Terminated
NCT01034657Phase 2

LBH589 Alone or in Combination With Erythropoietin Stimulating Agents (ESA) in Patients With Low or Int-1 Risk Myelodysplastic Syndromes (MDS)

Terminated
NCT01065467Phase 1

Panobinostat (LBH589) in Patients With Metastatic Melanoma

Completed

Drug Details

Intervention Type
DRUG
Total Trials
32