Success Metrics

Clinical Success Rate
89.8%

Based on 97 completed trials

Completion Rate
90%(97/108)
Active Trials
4(3%)
Results Posted
39%(38 trials)
Terminated
11(9%)

Phase Distribution

Ph not_applicable
12
10%
Ph phase_4
26
21%
Ph phase_3
27
22%
Ph phase_1
30
25%
Ph phase_2
16
13%

Phase Distribution

30

Early Stage

16

Mid Stage

53

Late Stage

Phase Distribution111 total trials
Phase 1Safety & dosage
30(27.0%)
Phase 2Efficacy & side effects
16(14.4%)
Phase 3Large-scale testing
27(24.3%)
Phase 4Post-market surveillance
26(23.4%)
N/ANon-phased studies
12(10.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

88.2%

97 of 110 finished

Non-Completion Rate

11.8%

13 ended early

Currently Active

4

trials recruiting

Total Trials

121

all time

Status Distribution
Active(5)
Completed(97)
Terminated(13)
Other(6)

Detailed Status

Completed97
Terminated11
unknown6
Recruiting4
Withdrawn2
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
121
Active
4
Success Rate
89.8%
Most Advanced
Phase 4

Trials by Phase

Phase 130 (27.0%)
Phase 216 (14.4%)
Phase 327 (24.3%)
Phase 426 (23.4%)
N/A12 (10.8%)

Trials by Status

unknown65%
not_yet_recruiting11%
completed9780%
withdrawn22%
recruiting43%
terminated119%

Recent Activity

Clinical Trials (121)

Showing 20 of 121 trialsScroll for more
NCT05450978

Physiological-based Pharmacokinetics Approach to Medication Exposure During Pregnancy and Breastfeeding

Recruiting
NCT06929273Phase 3

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

Recruiting
NCT06184581Phase 4

Lithium Versus Lamotrigine in Bipolar Disorder, Type II

Recruiting
NCT06729970Phase 1

A Study to Evaluate the Effects of Lithium, Valproic Acid, and Lamotrigine on the Pharmacokinetics of KarXT and Effects of KarXT on the Pharmacokinetics of Lithium, Valproic Acid, and Lamotrigine in Healthy Participants

Completed
NCT03196466

Population Pharmacokinetics of Antiepileptic in Pediatrics

Completed
NCT04770493Phase 2

Enhancing the Effects of Alcohol Treatment With Lamotrigine

Completed
NCT03497143

Bariatric Surgery and Pharmacokinetics of Lamotrigine

Recruiting
NCT00835263Phase 1

Bioequivalence Study of 200 mg Lamotrigine Tablet Under Non-Fasting Conditions

Completed
NCT00834561Phase 1

Bioequivalence Study of 200 mg Lamotrigine Tablet Under Fasting Conditions

Completed
NCT05881928Phase 4

Effect of Adding Lamotrigine to Sodium Valproate in Childhood Epilepsy: Clinicolabratory Study

Not Yet Recruiting
NCT04602221Phase 1

A Study in Healthy Men to Test Whether BI 409306, BI 425809 or Lamotrigine Can Reverse the Memory Problems Caused by Ketamine

Completed
NCT02893371

Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies

Terminated
NCT03504501Phase 2

Synaptic Plasticity and Cognitive Function in RASopathies

Terminated
NCT00007670Phase 3

Does Gabapentin and Lamotriginel Have Significantly Fewer Side-effects While Providing Equal or Better Seizure Control Than the Current Drug Choice, Carbamazepine, for the Treatment of Seizures in the Elderly.

Completed
NCT05697614Phase 4

The Benefit and Safety of Older Generation Anti-Epileptic Drugs (AEDs) in Drug-Resistant Epilepsy Children

Unknown
NCT05639257Not Applicable

Treatment of Myotonia - Lamotrigine Versus Namuscla

Unknown
NCT01996293

Pregnant Women Taking Lamictal for Bipolar Disorder

Completed
NCT01880957Not Applicable

PET and MRI Brain Imaging of Bipolar Disorder

Completed
NCT02158585Phase 2

Study of Lamotrigine to Treat Ménière's Disease

Completed
NCT04156035Not Applicable

Ketamine-Induced Brain Changes and Their Modulation by Lamotrigine

Completed

Drug Details

Intervention Type
DRUG
Total Trials
121