Success Metrics

Clinical Success Rate
89.4%

Based on 228 completed trials

Completion Rate
89%(228/255)
Active Trials
22(7%)
Results Posted
30%(68 trials)
Terminated
27(9%)

Phase Distribution

Ph not_applicable
3
1%
Ph phase_1
113
36%
Ph early_phase_1
3
1%
Ph phase_2
159
50%
Ph phase_3
36
11%
Ph phase_4
2
1%

Phase Distribution

116

Early Stage

159

Mid Stage

38

Late Stage

Phase Distribution316 total trials
Early Phase 1First-in-human
3(0.9%)
Phase 1Safety & dosage
113(35.8%)
Phase 2Efficacy & side effects
159(50.3%)
Phase 3Large-scale testing
36(11.4%)
Phase 4Post-market surveillance
2(0.6%)
N/ANon-phased studies
3(0.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

86.0%

228 of 265 finished

Non-Completion Rate

14.0%

37 ended early

Currently Active

22

trials recruiting

Total Trials

317

all time

Status Distribution
Active(25)
Completed(228)
Terminated(37)
Other(27)

Detailed Status

Completed228
Terminated27
unknown26
Active, not recruiting16
Withdrawn10
Recruiting6

Development Timeline

Analytics

Development Status

Total Trials
317
Active
22
Success Rate
89.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (0.9%)
Phase 1113 (35.8%)
Phase 2159 (50.3%)
Phase 336 (11.4%)
Phase 42 (0.6%)
N/A3 (0.9%)

Trials by Status

unknown268%
withdrawn103%
active_not_recruiting165%
completed22872%
not_yet_recruiting31%
suspended10%
recruiting62%
terminated279%

Recent Activity

Clinical Trials (317)

Showing 20 of 317 trialsScroll for more
NCT06662786Phase 3

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Recruiting
NCT06995872Phase 1

Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma

Recruiting
NCT06958328Phase 3

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

Recruiting
NCT00980460Phase 3

Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer

Active Not Recruiting
NCT02567435Phase 3

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Active Not Recruiting
NCT01787500Phase 1

Vemurafenib, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery

Completed
NCT00093353Phase 1

N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma

Completed
NCT00509353Phase 1

N2004-06: Irinotecan and Vincristine With 131I-MIBG Therapy for Resistant/Relapsed High-Risk Neuroblastoma

Completed
NCT02595931Phase 1

M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Active Not Recruiting
NCT00045201Phase 1

Erlotinib Hydrochloride and Irinotecan Hydrochloride in Treating Patients With Advanced Solid Tumors

Active Not Recruiting
NCT07518147Phase 3

A Study Comparing BL-M05D1 With the Investigator's Choice of Treatment Regimen in Patients With Claudin (CLDN)18.2-Positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma (GC/GEJC) Who Have Received Prior First-Line Treatment

Not Yet Recruiting
NCT02366819Phase 4

Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer

Suspended
NCT07466316Phase 3

A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

Not Yet Recruiting
NCT02047474Phase 2

Combination Chemotherapy Before and After Surgery in Treating Patients With Localized Pancreatic Cancer

Completed
NCT02890355Phase 2

FOLFIRI or Modified FOLFIRI and Veliparib as Second Line Therapy in Treating Patients With Metastatic Pancreatic Cancer

Active Not Recruiting
NCT04094688Phase 3

Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

Active Not Recruiting
NCT03794349Phase 2

Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma

Active Not Recruiting
NCT06820957Phase 2

Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body

Active Not Recruiting
NCT04340141Phase 3

Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer

Active Not Recruiting
NCT03365882Phase 2

S1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

Completed

Drug Details

Intervention Type
DRUG
Total Trials
317