Interleukin-2
Interleukin-2 is a biological therapy with 147 clinical trials. Currently 33 active trials ongoing. Historical success rate of 72.3%.
Success Metrics
Based on 60 completed trials
Phase Distribution
Phase Distribution
70
Early Stage
59
Mid Stage
11
Late Stage
Highest Phase Reached
Phase 4Trial Status & Enrollment
68.2%
60 of 88 finished
31.8%
28 ended early
33
trials recruiting
147
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
CIML NK Cells With Venetoclax for AML
Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)
"Re-Stimulated" TILs And IL-2 Therapy for Platinum Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Interleukin-2 and Pembrolizumab for Metastatic Kidney Cancer
Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma
Clinical Trials (147)
CIML NK Cells With Venetoclax for AML
Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)
"Re-Stimulated" TILs And IL-2 Therapy for Platinum Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Interleukin-2 and Pembrolizumab for Metastatic Kidney Cancer
Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma
Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled Study
A FIH, Phase I/IIa, Trial Assessing Feasibility of Administrations of TIL-based Immunotherapy in Patients With Metastatic CRC and PC
Ph1 T-Regulatory Cells in Amyotrophic Lateral Sclerosis
Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation
A Phase 1/2 Study of KSQ-004EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate Genes Encoding SOCS1 and Regnase-1, in Patients With Select Advanced Solid Tumors
Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma
Therapy for Children With Advanced Stage Neuroblastoma
Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma
IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients
Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma
Lymphodepletion Plus Adoptive Cell Therapy With High Dose IL-2 in Adolescent and Young Adult Patients With Soft Tissue Sarcoma
A Phase II Trial of Low-Dose Interleukin-2 (IL-2) Added to Extra-Corporeal Photopheresis for Steroid-Refractory cGVHD
Daily IL-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease
A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors
TIL Therapy in cSCC and MCC
Drug Details
- Intervention Type
- BIOLOGICAL
- Total Trials
- 147