Success Metrics

Clinical Success Rate

62.5%

Based on 15 completed trials

Completion Rate

63%(15/24)

Active Trials

1(3%)

Results Posted

60%(9 trials)

Terminated

9(23%)

Phase Distribution

Ph phase_4

Ph phase_1

15%

Ph phase_3

30%

Ph early_phase_1

Ph phase_2

28%

Ph not_applicable

10%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution38 total trials

Early Phase 1First-in-human

2(5.3%)

Phase 1Safety & dosage

6(15.8%)

Phase 2Efficacy & side effects

11(28.9%)

Phase 3Large-scale testing

12(31.6%)

Phase 4Post-market surveillance

3(7.9%)

N/ANon-phased studies

4(10.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

53.6%

15 of 28 finished

Non-Completion Rate

46.4%

13 ended early

Currently Active

trials recruiting

Total Trials

all time

Status Distribution

Active(4)

Completed(15)

Terminated(13)

Other(8)

Detailed Status

Completed15

Terminated9

unknown8

Withdrawn4

Not yet recruiting2

Enrolling by invitation1

Development Timeline

Analytics

Development Status

Total Trials

Active

Success Rate

62.5%

Most Advanced

Phase 4

Trials by Phase

Early Phase 12 (5.3%)

Phase 16 (15.8%)

Phase 211 (28.9%)

Phase 312 (31.6%)

Phase 43 (7.9%)

N/A4 (10.5%)

Trials by Status

terminated923%

enrolling_by_invitation13%

unknown820%

active_not_recruiting13%

withdrawn410%

completed1538%

not_yet_recruiting25%

Recent Activity

1 active trials

Showing 5 of 40

not_yet_recruitingphase_1

Clinical Trials (40)

Showing 20 of 40 trialsScroll for more

NCT04231760Phase 1

The Effect of Inhaled Nitric Oxide on Pulmonary Gas-exchange in COPD

Not Yet Recruiting

NCT05612074Early Phase 1

Methemoglobin Concentration in High Dose Inhaled Nitric Oxide

Active Not Recruiting

NCT07247240Phase 4

Efficacy of Inhaled Nitric Oxide in Congenital Diaphragmatic Hernia

Not Yet Recruiting

NCT05616910Phase 2

Inhaled Nitric Oxide for Microvascular Dysfunction in Traumatic Brain Injury

Enrolling By Invitation

NCT03260569Phase 3

Inhaled Nitric Oxide in Brain Injury

Completed

NCT03576885Phase 1

Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia

Terminated

NCT00515281Phase 2

Inhaled Nitric Oxide and Neuroprotection in Premature Infants

Terminated

NCT02151877Not Applicable

Efficacy of Nitric Oxide Administration in Attenuating Ischemia/Reperfusion Injury During Neonatal Cardiopulmonary Bypass

Completed

NCT02652429Phase 3

Long-Term Extension Study of Inhaled Nitric Oxide (iNO) for PAH

Unknown

NCT05587400Not Applicable

Consistency of Electrical Cardiometry and Pulmonary Artery Catheter

Unknown

NCT04988932Not Applicable

Inhaled Nitric Oxide Treatment for Aneurysmal SAH Patients With Intractable Cerebral Vasospasm

Completed

NCT04224103

Nitric Oxide in Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO)

Unknown

NCT04032366

iNO as Salvage Treatment of Hypoxemia After TAAD Surgery

Unknown

NCT01891500Phase 4

Early iNO for Oxidative Stress, Vascular Tone and Inflammation in Babies With Hypoxic Respiratory Failure

Withdrawn

NCT03873298Phase 2

Inhaled NO in IPF and COPD During 6 Minute Walk Test

Unknown

NCT04134078Early Phase 1

Improving Outcomes in Cardiac Arrest With Inhaled Nitric Oxide

Unknown

NCT02851472Phase 1

Prevention of Transfusion Related Acute Gut Injury (TRAGI) in Extremely Low Gestational Age Neonates (ELGANs) Using iNO

Unknown

NCT01939301Phase 2

Nitric Oxide to Treat Pulmonary Embolism

Completed

NCT00001303Phase 1

Effects of Endotoxin in Normal Human Volunteers

Completed

NCT01607983Phase 3

Effects of Pulmonary Vasodilation Upon VA Coupling in Fontan Patients

Withdrawn

Drug Details

Intervention Type: DRUG
Total Trials: 40