Success Metrics

Clinical Success Rate
76.2%

Based on 64 completed trials

Completion Rate
76%(64/84)
Active Trials
28(19%)
Results Posted
58%(37 trials)
Terminated
20(13%)

Phase Distribution

Ph phase_2
65
44%
Ph early_phase_1
1
1%
Ph not_applicable
1
1%
Ph phase_3
39
26%
Ph phase_4
9
6%
Ph phase_1
23
15%

Phase Distribution

24

Early Stage

65

Mid Stage

48

Late Stage

Phase Distribution138 total trials
Early Phase 1First-in-human
1(0.7%)
Phase 1Safety & dosage
23(16.7%)
Phase 2Efficacy & side effects
65(47.1%)
Phase 3Large-scale testing
39(28.3%)
Phase 4Post-market surveillance
9(6.5%)
N/ANon-phased studies
1(0.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.6%

64 of 87 finished

Non-Completion Rate

26.4%

23 ended early

Currently Active

28

trials recruiting

Total Trials

149

all time

Status Distribution
Active(34)
Completed(64)
Terminated(23)
Other(28)

Detailed Status

Completed64
unknown28
Terminated20
Recruiting16
Active, not recruiting12
Not yet recruiting6

Development Timeline

Analytics

Development Status

Total Trials
149
Active
28
Success Rate
76.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.7%)
Phase 123 (16.7%)
Phase 265 (47.1%)
Phase 339 (28.3%)
Phase 49 (6.5%)
N/A1 (0.7%)

Trials by Status

unknown2819%
active_not_recruiting128%
not_yet_recruiting64%
withdrawn32%
completed6443%
recruiting1611%
terminated2013%

Recent Activity

Clinical Trials (149)

Showing 20 of 149 trialsScroll for more
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT04307576Phase 3

A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

Recruiting
NCT05816785Early Phase 1

Pilot Study of Imatinib Cetuximab Combo for H & N Cancer

Active Not Recruiting
NCT06090669Phase 1

Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency

Recruiting
NCT03578367Phase 2

Study of Efficacy and Safety of Asciminib in Combination With Imatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Who Have Been Previously Treated With Imatinib and Have Not Achieved Deep Molecular Response.

Completed
NCT07530367Phase 3

A Phase III Randomized Controlled Trial Evaluating the Efficacy and Safety of Tofacitinib Combined With Imatinib in Patients With Moderate-to-Severe Palmoplantar Pustulosis

Not Yet Recruiting
NCT07493408Phase 2

Asciminib & Standard-of-Care Integration in Maintenance Therapy for POST Allogeneic Stem Cell Transplant (Allo-HSCT) of Patient With Ph+ B-ALL or Blastic Transformed CML

Not Yet Recruiting
NCT07171203Phase 1

Neoadjuvant Imatinib and Fampridine in KIT Mutant Gastrointestinal Stromal Tumor

Recruiting
NCT04394416Phase 3

Trial of Imatinib for Hospitalized Adults With COVID-19

Terminated
NCT00044304Phase 2

Tyrosine Kinase Inhibition to Treat Myeloid Hypereosinophilic Syndrome

Active Not Recruiting
NCT00421317Phase 2

Imatinib in Adult Patients With Metastatic Ocular Melanoma

Terminated
NCT04971226Phase 3

A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP

Active Not Recruiting
NCT04877522Phase 4

Asciminib Roll-over Study

Recruiting
NCT05493215Phase 2

Imatinib TDM in GIST

Recruiting
NCT05245968Phase 1

A Study of Pimitespib in Combination With Imatinib in Patients With GIST (CHAPTER-GIST-101)

Active Not Recruiting
NCT03654768Phase 2

Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

Active Not Recruiting
NCT02881086Phase 3

Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment

Completed
NCT06682169Phase 3

Evaluation of Rovadicitinib Compared to the Protocol Selected by Researchers in Third Line and Subsequent Studies of Moderate to Severe Chronic Graft-versus-host Disease

Recruiting
NCT03589326Phase 3

A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT04070443Phase 2

Safety and Efficacy of Ponatinib Followed by Imatinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
149