Success Metrics

Clinical Success Rate
83.7%

Based on 170 completed trials

Completion Rate
84%(170/203)
Active Trials
50(16%)
Results Posted
49%(84 trials)
Terminated
33(11%)

Phase Distribution

Ph early_phase_1
4
1%
Ph phase_3
73
24%
Ph not_applicable
17
6%
Ph phase_4
5
2%
Ph phase_2
149
48%
Ph phase_1
60
19%

Phase Distribution

64

Early Stage

149

Mid Stage

78

Late Stage

Phase Distribution308 total trials
Early Phase 1First-in-human
4(1.3%)
Phase 1Safety & dosage
60(19.5%)
Phase 2Efficacy & side effects
149(48.4%)
Phase 3Large-scale testing
73(23.7%)
Phase 4Post-market surveillance
5(1.6%)
N/ANon-phased studies
17(5.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.6%

170 of 211 finished

Non-Completion Rate

19.4%

41 ended early

Currently Active

50

trials recruiting

Total Trials

309

all time

Status Distribution
Active(50)
Completed(170)
Terminated(41)
Other(48)

Detailed Status

Completed170
unknown47
Terminated33
Active, not recruiting25
Recruiting25
Withdrawn8

Development Timeline

Analytics

Development Status

Total Trials
309
Active
50
Success Rate
83.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (1.3%)
Phase 160 (19.5%)
Phase 2149 (48.4%)
Phase 373 (23.7%)
Phase 45 (1.6%)
N/A17 (5.5%)

Trials by Status

terminated3311%
completed17055%
active_not_recruiting258%
recruiting258%
unknown4715%
withdrawn83%
suspended10%

Recent Activity

Clinical Trials (309)

Showing 20 of 309 trialsScroll for more
NCT07321912Phase 2

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

Recruiting
NCT04833114Phase 3

Polatuzumab Vedotin Plus Rituximab, Ifosfamide, Carboplatin and Etoposide (Pola-R-ICE) Versus R-ICE Alone in Second Line Treatment of Diffuse Large B-cell Lymphoma (DLBCL)

Completed
NCT06239272Phase 1

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

Recruiting
NCT02306161Phase 3

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Active Not Recruiting
NCT05533775Phase 1

A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

Recruiting
NCT02112916Phase 3

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

Active Not Recruiting
NCT03016871Phase 2

Nivolumab, Ifosfamide, Carboplatin, and Etoposide as Second-Line Therapy in Treating Patients With Refractory or Relapsed HL

Active Not Recruiting
NCT00077285Phase 2

Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma

Active Not Recruiting
NCT07194044Phase 1

Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes

Recruiting
NCT05221645Phase 2

Pembrolizumab in Combination With R-ICE Chemotherapy in Relapsed/Refractory Diffuse Large B-cell Lymphoma

Active Not Recruiting
NCT06230224Phase 3

A Trial to Learn How Effective and Safe Odronextamab is Compared to Standard of Care for Adult Participants With Previously Treated Aggressive B-cell Non-Hodgkin Lymphoma

Active Not Recruiting
NCT04043494Phase 3

International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma

Recruiting
NCT04322318Phase 2

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Recruiting
NCT04684368Phase 2

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Recruiting
NCT06647953Phase 3

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

Recruiting
NCT02180867Phase 2

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Active Not Recruiting
NCT03007147Phase 3

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03206671Phase 3

Treatment Protocol of the NHL-BFM and the NOPHO Study Groups for Mature Aggressive B-cell Lymphoma and Leukemia in Children and Adolescents

Active Not Recruiting
NCT01871766Phase 2

Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

Active Not Recruiting
NCT04968106Phase 2

Neoadjuvant Chemotherapy and Retifanlimab in Patients With Selected Sarcomas (TORNADO)

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
309