Success Metrics

Clinical Success Rate
79.0%

Based on 132 completed trials

Completion Rate
79%(132/167)
Active Trials
83(29%)
Results Posted
89%(117 trials)
Terminated
35(12%)

Phase Distribution

Ph phase_2
123
43%
Ph phase_1
108
38%
Ph phase_3
39
14%
Ph phase_4
2
1%
Ph early_phase_1
2
1%

Phase Distribution

110

Early Stage

123

Mid Stage

41

Late Stage

Phase Distribution274 total trials
Early Phase 1First-in-human
2(0.7%)
Phase 1Safety & dosage
108(39.4%)
Phase 2Efficacy & side effects
123(44.9%)
Phase 3Large-scale testing
39(14.2%)
Phase 4Post-market surveillance
2(0.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.4%

132 of 185 finished

Non-Completion Rate

28.6%

53 ended early

Currently Active

83

trials recruiting

Total Trials

284

all time

Status Distribution
Active(84)
Completed(132)
Terminated(53)
Other(15)

Detailed Status

Completed132
Active, not recruiting62
Terminated35
Recruiting21
Withdrawn18
unknown15

Development Timeline

Analytics

Development Status

Total Trials
284
Active
83
Success Rate
79.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (0.7%)
Phase 1108 (39.4%)
Phase 2123 (44.9%)
Phase 339 (14.2%)
Phase 42 (0.7%)

Trials by Status

active_not_recruiting6222%
not_yet_recruiting10%
terminated3512%
unknown155%
withdrawn186%
completed13246%
recruiting217%

Recent Activity

Clinical Trials (284)

Showing 20 of 284 trialsScroll for more
NCT02048813Phase 3

Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Active Not Recruiting
NCT02443077Phase 3

Ibrutinib Before and After Stem Cell Transplant in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

Active Not Recruiting
NCT01804686Phase 3

A Long-term Extension Study of PCI-32765 (Ibrutinib)

Recruiting
NCT05963074Phase 2

A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT02756897Phase 2

Venetoclax and Ibrutinib in Treating Patients With Chronic or Small Lymphocytic Leukemia

Active Not Recruiting
NCT04840602Phase 2

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

Recruiting
NCT03223610Phase 1

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

Recruiting
NCT03478514Phase 2

Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma

Active Not Recruiting
NCT04212013Phase 3

A Study of Ibrutinib With Rituximab in People With Untreated Marginal Zone Lymphoma

Active Not Recruiting
NCT02251548Phase 2

A Phase II Study of Ibrutinib Plus FCR in Previously Untreated, Younger Patients With Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT06136559Phase 3

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Recruiting
NCT03701282Phase 3

Assessing the Ability of Combination Treatment With Venetoclax to Permit Time Limited Therapy in Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT05254743Phase 3

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Recruiting
NCT03737981Phase 3

Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT03282396Phase 2

Ibrutinib in Treating Participants With Untreated High Risk Smoldering Mantle Cell Lymphoma

Active Not Recruiting
NCT06649812Phase 2

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Recruiting
NCT07082868Phase 1

A Study of Epcoritamab and Ibrutinib in People With Central Nervous System Lymphoma (CNSL)

Recruiting
NCT01880567Phase 2

Ibrutinib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Older Patients With Newly Diagnosed Mantle Cell Lymphoma

Active Not Recruiting
NCT05283720Phase 2

A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma

Active Not Recruiting
NCT03021460Phase 1

Pembrolizumab and Ibrutinib in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
284