Success Metrics

Clinical Success Rate
81.4%

Based on 57 completed trials

Completion Rate
81%(57/70)
Active Trials
13(14%)
Results Posted
68%(39 trials)
Terminated
13(14%)

Phase Distribution

Ph early_phase_1
4
4%
Ph phase_3
8
9%
Ph not_applicable
15
17%
Ph phase_4
35
39%
Ph phase_1
7
8%
Ph phase_2
17
19%

Phase Distribution

11

Early Stage

17

Mid Stage

43

Late Stage

Phase Distribution86 total trials
Early Phase 1First-in-human
4(4.7%)
Phase 1Safety & dosage
7(8.1%)
Phase 2Efficacy & side effects
17(19.8%)
Phase 3Large-scale testing
8(9.3%)
Phase 4Post-market surveillance
35(40.7%)
N/ANon-phased studies
15(17.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

79.2%

57 of 72 finished

Non-Completion Rate

20.8%

15 ended early

Currently Active

13

trials recruiting

Total Trials

90

all time

Status Distribution
Active(13)
Completed(57)
Terminated(15)
Other(5)

Detailed Status

Completed57
Terminated13
Recruiting11
unknown5
Withdrawn2
Active, not recruiting2

Development Timeline

Analytics

Development Status

Total Trials
90
Active
13
Success Rate
81.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (4.7%)
Phase 17 (8.1%)
Phase 217 (19.8%)
Phase 38 (9.3%)
Phase 435 (40.7%)
N/A15 (17.4%)

Trials by Status

withdrawn22%
recruiting1112%
terminated1314%
active_not_recruiting22%
unknown56%
completed5763%

Recent Activity

Clinical Trials (90)

Showing 20 of 90 trialsScroll for more
NCT05610072Early Phase 1

Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine)

Completed
NCT03427736

Anesthetics and Analgesics in Children

Recruiting
NCT07224620Phase 2

Fentanyl Versus Hydromorphone in Patients on Mechanical Ventilation

Recruiting
NCT06784180Phase 4

Intrathecal Hydromorphone vs Intrathecal Morphine to Treat Post Cesarean Pain in Patients With Opioid Use Disorder Taking Buprenorphine

Withdrawn
NCT06525740Phase 4

Methadone Versus Intrathecal Hydromorphone for Postoperative Pain Relief in Gynecologic Cancer Undergoing Surgery

Recruiting
NCT06411795Phase 2

Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy

Recruiting
NCT04296305Phase 4

Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer Pain

Active Not Recruiting
NCT03726268Phase 4

Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)

Completed
NCT06868589Phase 4

Reducing Pain With Methadone and Ketamine in Liver Transplant

Recruiting
NCT06949059Phase 1

Intravenous Hydromorphone for the Treatment of Acute Pain

Recruiting
NCT05027919Phase 2

Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

Recruiting
NCT05842044Phase 2

NSAID Use After Robotic Partial Nephrectomy

Recruiting
NCT03579446Early Phase 1

Levorphanol as a Second Line Opioid in Reducing Pain in Patients With Cancer

Terminated
NCT06406400Phase 1

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Terminated
NCT04230681Early Phase 1

Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery

Completed
NCT06669650Phase 4

Personalized Post-Operative Pain Management

Active Not Recruiting
NCT04258631Phase 4

Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological Malignancies

Completed
NCT03767933Phase 2

Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries

Completed
NCT05565495Phase 2

The Effects of ECMO on the Pharmacokinetics of Hydromorphone

Recruiting
NCT04234191Phase 2

Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
90