Success Metrics

Clinical Success Rate
73.1%

Based on 136 completed trials

Completion Rate
73%(136/186)
Active Trials
121(33%)
Results Posted
97%(132 trials)
Terminated
50(14%)

Phase Distribution

Ph phase_1
115
32%
Ph not_applicable
3
1%
Ph phase_4
6
2%
Ph early_phase_1
2
1%
Ph phase_3
57
16%
Ph phase_2
166
46%

Phase Distribution

117

Early Stage

166

Mid Stage

63

Late Stage

Phase Distribution349 total trials
Early Phase 1First-in-human
2(0.6%)
Phase 1Safety & dosage
115(33.0%)
Phase 2Efficacy & side effects
166(47.6%)
Phase 3Large-scale testing
57(16.3%)
Phase 4Post-market surveillance
6(1.7%)
N/ANon-phased studies
3(0.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

67.7%

136 of 201 finished

Non-Completion Rate

32.3%

65 ended early

Currently Active

121

trials recruiting

Total Trials

363

all time

Status Distribution
Active(134)
Completed(136)
Terminated(65)
Other(28)

Detailed Status

Completed136
Active, not recruiting61
Recruiting60
Terminated50
unknown28
Withdrawn15

Development Timeline

Analytics

Development Status

Total Trials
363
Active
121
Success Rate
73.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (0.6%)
Phase 1115 (33.0%)
Phase 2166 (47.6%)
Phase 357 (16.3%)
Phase 46 (1.7%)
N/A3 (0.9%)

Trials by Status

completed13637%
unknown288%
active_not_recruiting6117%
recruiting6017%
not_yet_recruiting134%
terminated5014%
withdrawn154%

Recent Activity

Clinical Trials (363)

Showing 20 of 363 trialsScroll for more
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT06625775Phase 1

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Recruiting
NCT05161195Phase 4

Roll-over Study to Allow Continued Access to Ribociclib

Active Not Recruiting
NCT05038735Phase 3

Study to Assess the Efficacy and Safety of Alpelisib Plus Fulvestrant in Participants With HR-positive (HR+), HER2-negative, Advanced Breast Cancer After Treatment With a CDK4/6 Inhibitor and an Aromatase Inhibitor.

Active Not Recruiting
NCT06120283Phase 1

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

Recruiting
NCT05867251Phase 1

Study of AVZO-021 in Patients With Advanced Solid Tumors

Recruiting
NCT06110793Phase 1

A Study of Lenvatinib, Pembrolizumab, and Fulvestrant in People With Breast Cancer

Active Not Recruiting
NCT05646862Phase 3

A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy

Recruiting
NCT07226349Phase 1

A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors

Recruiting
NCT03643510Phase 2

Evaluating Cancer Response to Treatment With Abemaciclib and Fulvestrant in Women With Recurrent Endometrial Cancer

Completed
NCT06979596Phase 2

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

Recruiting
NCT02860000Phase 2

Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer

Completed
NCT04224272Phase 2

Phase 2a Study of ZW25 in Combination With Palbociclib Plus Fulvestrant

Completed
NCT06179303Phase 2

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

Recruiting
NCT05384119Phase 1

Phase 1b/2 Study of TTI-101 in Combination for Patients With Metastatic Hormone Receptor-Positive and HER2-Negative Breast Cancer

Terminated
NCT07174336Phase 3

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Recruiting
NCT04524000Phase 2

Study Assessing the Efficacy and Safety of Treatment With Alpelisib Plus Fulvestrant in Japanese Men and Postmenopausal Women With Advanced Breast Cancer

Active Not Recruiting
NCT04544189Phase 2

Study Assessing the Efficacy and Safety of Treatment With Alpelisib Plus Fulvestrant Versus Placebo Plus Fulvestrant in Chinese Men and Postmenopausal Women With Advanced Breast Cancer

Active Not Recruiting
NCT07679269Phase 2

Roll-Over Study of Alpelisib (BYL719) for Continued Access and Long-Term Safety.

Not Yet Recruiting
NCT07748208Phase 2

A Study Evaluating the Safety of Inavolisib and Fulvestrant With or Without Palbociclib in Participants With Advanced Breast Cancer (ABC) and Type 2 Diabetes

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
363