Success Metrics

Clinical Success Rate
81.4%

Based on 48 completed trials

Completion Rate
81%(48/59)
Active Trials
18(20%)
Results Posted
50%(24 trials)
Terminated
11(12%)

Phase Distribution

Ph early_phase_1
1
1%
Ph phase_1
36
39%
Ph phase_3
11
12%
Ph phase_2
43
47%

Phase Distribution

37

Early Stage

43

Mid Stage

11

Late Stage

Phase Distribution91 total trials
Early Phase 1First-in-human
1(1.1%)
Phase 1Safety & dosage
36(39.6%)
Phase 2Efficacy & side effects
43(47.3%)
Phase 3Large-scale testing
11(12.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

77.4%

48 of 62 finished

Non-Completion Rate

22.6%

14 ended early

Currently Active

18

trials recruiting

Total Trials

92

all time

Status Distribution
Active(21)
Completed(48)
Terminated(14)
Other(9)

Detailed Status

Completed48
Recruiting14
Terminated11
unknown8
Active, not recruiting4
Withdrawn3

Development Timeline

Analytics

Development Status

Total Trials
92
Active
18
Success Rate
81.4%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (1.1%)
Phase 136 (39.6%)
Phase 243 (47.3%)
Phase 311 (12.1%)

Trials by Status

terminated1112%
suspended11%
completed4852%
unknown89%
recruiting1415%
withdrawn33%
not_yet_recruiting33%
active_not_recruiting44%

Recent Activity

Clinical Trials (92)

Showing 20 of 92 trialsScroll for more
NCT07221357Phase 2

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Recruiting
NCT07446322Phase 2

FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer

Recruiting
NCT06179160Phase 1

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Recruiting
NCT05004350Phase 2

A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer.

Completed
NCT07381309Phase 2

Oncolytic Virus (H101) + SBRT + Chemotherapy + Targeted Therapy + Immunotherapy for Unresectable CRLM

Not Yet Recruiting
NCT04929223Phase 1

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

Recruiting
NCT05786924Phase 1

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Recruiting
NCT03081143Phase 2

Ramucirumab Plus FOLFIRI Versus Ramucirumab Plus Paclitaxel in Patients With Advanced or Metastatic Gastric Cancer, Who Failed One Prior Line of Palliative Chemotherapy

Active Not Recruiting
NCT06663319Phase 1

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

Recruiting
NCT03798626Phase 1

Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorectal, Gastroesophageal, and Renal Cancers

Completed
NCT05733689Phase 1

Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial)

Recruiting
NCT07318389Early Phase 1

ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic Colorectal Cancer

Not Yet Recruiting
NCT05419479Phase 1

Switch Maintenance in Pancreatic

Suspended
NCT04485013Phase 1

TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

Recruiting
NCT07323576Phase 2

A Study to Evaluate the Efficacy and Safety of Inavolisib When Administered in Combination With Bevacizumab and FOLFOX or FOLFIRI as First Line Therapy in Participants With Colorectal Cancer

Withdrawn
NCT00208260Phase 2

Intensified Chemotherapy in CRC After Resection of Liver Metastases

Completed
NCT06106308Phase 2

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation

Active Not Recruiting
NCT05836324Phase 1

A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors

Recruiting
NCT05008809Phase 3

Post-resection/Ablation Chemotherapy in Patients With Metastatic Colorectal Cancer (FIRE-9 - PORT / AIO-KRK-0418)

Recruiting
NCT06747845Phase 2

Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
92