Success Metrics

Clinical Success Rate
82.7%

Based on 580 completed trials

Completion Rate
83%(580/701)
Active Trials
217(19%)
Results Posted
55%(321 trials)
Terminated
121(11%)

Phase Distribution

Ph phase_1
266
24%
Ph early_phase_1
12
1%
Ph not_applicable
34
3%
Ph phase_2
556
50%
Ph phase_3
243
22%
Ph phase_4
7
1%

Phase Distribution

278

Early Stage

556

Mid Stage

250

Late Stage

Phase Distribution1118 total trials
Early Phase 1First-in-human
12(1.1%)
Phase 1Safety & dosage
266(23.8%)
Phase 2Efficacy & side effects
556(49.7%)
Phase 3Large-scale testing
243(21.7%)
Phase 4Post-market surveillance
7(0.6%)
N/ANon-phased studies
34(3.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.6%

580 of 738 finished

Non-Completion Rate

21.4%

158 ended early

Currently Active

217

trials recruiting

Total Trials

1,121

all time

Status Distribution
Active(234)
Completed(580)
Terminated(158)
Other(149)

Detailed Status

Completed580
unknown146
Terminated121
Recruiting110
Active, not recruiting107
Withdrawn37

Development Timeline

Analytics

Development Status

Total Trials
1121
Active
217
Success Rate
82.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 112 (1.1%)
Phase 1266 (23.8%)
Phase 2556 (49.7%)
Phase 3243 (21.7%)
Phase 47 (0.6%)
N/A34 (3.0%)

Trials by Status

active_not_recruiting10710%
completed58052%
withdrawn373%
not_yet_recruiting161%
enrolling_by_invitation10%
terminated12111%
suspended30%
unknown14613%
recruiting11010%

Recent Activity

Clinical Trials (1,121)

Showing 20 of 1,121 trialsScroll for more
NCT06406465Phase 2

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT07227597Phase 1

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

Recruiting
NCT07321912Phase 2

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

Recruiting
NCT07005128Phase 3

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

Recruiting
NCT05058651Phase 2

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

Recruiting
NCT05675410Phase 3

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Recruiting
NCT04728230Phase 1

Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial

Active Not Recruiting
NCT04833114Phase 3

Polatuzumab Vedotin Plus Rituximab, Ifosfamide, Carboplatin and Etoposide (Pola-R-ICE) Versus R-ICE Alone in Second Line Treatment of Diffuse Large B-cell Lymphoma (DLBCL)

Completed
NCT06077500Phase 1

DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer

Active Not Recruiting
NCT07472517Phase 3

DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy

Recruiting
NCT07155174Phase 2

A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

Recruiting
NCT06132113Phase 1

DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers

Active Not Recruiting
NCT07544654Phase 3

DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

Not Yet Recruiting
NCT05091567Phase 3

A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer

Active Not Recruiting
NCT06497530Phase 2

Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC

Recruiting
NCT01993810Phase 3

Comparing Photon Therapy To Proton Therapy To Treat Patients With Lung Cancer

Active Not Recruiting
NCT04699838Phase 2

Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

Recruiting
NCT04177004Phase 1

Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant

Active Not Recruiting
NCT06942039Early Phase 1

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,121