Success Metrics

Clinical Success Rate
90.4%

Based on 47 completed trials

Completion Rate
90%(47/52)
Active Trials
5(7%)
Results Posted
62%(29 trials)
Terminated
5(7%)

Phase Distribution

Ph phase_4
10
13%
Ph not_applicable
16
21%
Ph phase_1
4
5%
Ph phase_3
14
18%
Ph phase_2
25
33%
Ph early_phase_1
3
4%

Phase Distribution

7

Early Stage

25

Mid Stage

24

Late Stage

Phase Distribution72 total trials
Early Phase 1First-in-human
3(4.2%)
Phase 1Safety & dosage
4(5.6%)
Phase 2Efficacy & side effects
25(34.7%)
Phase 3Large-scale testing
14(19.4%)
Phase 4Post-market surveillance
10(13.9%)
N/ANon-phased studies
16(22.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.0%

47 of 58 finished

Non-Completion Rate

19.0%

11 ended early

Currently Active

5

trials recruiting

Total Trials

76

all time

Status Distribution
Active(6)
Completed(47)
Terminated(11)
Other(12)

Detailed Status

Completed47
unknown12
Withdrawn6
Terminated5
Recruiting4
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
76
Active
5
Success Rate
90.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (4.2%)
Phase 14 (5.6%)
Phase 225 (34.7%)
Phase 314 (19.4%)
Phase 410 (13.9%)
N/A16 (22.2%)

Trials by Status

active_not_recruiting11%
withdrawn68%
not_yet_recruiting11%
recruiting45%
unknown1216%
terminated57%
completed4762%

Recent Activity

Clinical Trials (76)

Showing 20 of 76 trialsScroll for more
NCT05716516Phase 2

STUDY02001740;22SCH740: Estradiol For ER+ Advanced Breast Cancer (ESTHER)

Recruiting
NCT06005610Phase 2

Estradiol Therapy In Transgender Women to Research Interactions With HIV Therapy

Terminated
NCT05457972Phase 4

Postpartum Vaginal Estrogen for Breastfeeding Patients

Recruiting
NCT04192266Phase 3

Estrogen and Fear in PTSD

Completed
NCT00001481Phase 2

The Role of Hormones in Postpartum Mood Disorders

Completed
NCT06369363Early Phase 1

Estrogen Deficiency on Cardiovascular Risk

Not Yet Recruiting
NCT03689543Phase 2

Estrogen Receptor Beta and Mood

Completed
NCT03401047Early Phase 1

Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome

Recruiting
NCT06247267

The Effect of Sex Steroid Replacement Therapy in the Hypogonadism and Transgender Active-Duty Population

Recruiting
NCT06253702Phase 4

Brain Blood Flow Responses to Stress: Sex Differences

Completed
NCT02238808Phase 2

A Study to See Whether Estrogen Can Slow the Growth of Some ER Positive Breast Cancers

Active Not Recruiting
NCT04036500Early Phase 1

Transgender Estradiol

Completed
NCT05617820Phase 3

Study Comparing Estradiol Vaginal Inserts 4mcg To IMVEXXY ® (Estradiol Vaginal Inerts 4 mcg) In The Treatment Of Dyspareunia in Women With Vulvur and Vaginal Atrophy

Completed
NCT04301934Not Applicable

Fractional CO2 Vaginal LASER Therapy for Recurrent Urinary Tract Infection

Completed
NCT06116201Not Applicable

Influences of Long Term Hormone Therapy on Physical Fitness and Vascular Function in Transgender Women

Completed
NCT05951413Phase 2

The Effect of Sildenafil Citrate on Frozen Embryo Transfer Cycles

Unknown
NCT05783479Not Applicable

Pharmacological Preparation of the Cervix for Hysteroscopy

Completed
NCT03236545Not Applicable

Menopause Effects on Vascular Function

Completed
NCT04225221Phase 2

Neurobiology of Bulimia Nervosa

Completed
NCT04933240Phase 4

Tamoxifen Versus Estradiol for Unscheduled Bleeding in Etonogestrel Implant Users, a Randomized Pilot Trial

Withdrawn

Drug Details

Intervention Type
DRUG
Total Trials
76