Success Metrics

Clinical Success Rate
66.7%

Based on 2 completed trials

Completion Rate
67%(2/3)
Active Trials
10(43%)
Results Posted
150%(3 trials)
Terminated
1(4%)

Phase Distribution

Ph phase_3
2
9%
Ph phase_1
6
26%
Ph phase_2
12
52%
Ph phase_4
1
4%

Phase Distribution

6

Early Stage

12

Mid Stage

3

Late Stage

Phase Distribution21 total trials
Phase 1Safety & dosage
6(28.6%)
Phase 2Efficacy & side effects
12(57.1%)
Phase 3Large-scale testing
2(9.5%)
Phase 4Post-market surveillance
1(4.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

66.7%

2 of 3 finished

Non-Completion Rate

33.3%

1 ended early

Currently Active

10

trials recruiting

Total Trials

23

all time

Status Distribution
Active(16)
Completed(2)
Terminated(1)
Other(4)

Detailed Status

Not yet recruiting6
Recruiting5
Active, not recruiting5
unknown4
Completed2
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
23
Active
10
Success Rate
66.7%
Most Advanced
Phase 4

Trials by Phase

Phase 16 (28.6%)
Phase 212 (57.1%)
Phase 32 (9.5%)
Phase 41 (4.8%)

Trials by Status

unknown417%
terminated14%
recruiting522%
active_not_recruiting522%
not_yet_recruiting626%
completed29%

Recent Activity

Clinical Trials (23)

Showing 20 of 23 trialsScroll for more
NCT03155620Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Active Not Recruiting
NCT03213652Phase 2

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Active Not Recruiting
NCT03420508Phase 2

Treating Patients With Melanoma and ALK Alterations With Ensartinib

Active Not Recruiting
NCT05491811Phase 2

Ensartinib in Combination With Bevacizumab in ALK-positive NSCLC Patients With TP53 Mutation

Active Not Recruiting
NCT03737994Phase 2

Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer

Terminated
NCT06563999Phase 2

Neoadjuvant Umbrella Trial for Patients With Unresectable Stage III NSCLC Harboring Rare Mutations.

Recruiting
NCT07448116Phase 1

Study of MCLA-129 in Combination With Ensartinib in Patients With Advanced Solid Tumors.

Recruiting
NCT04837716Phase 1

Ensartinib, Carboplatin, Pemetrexed and Bevacizumab for the Treatment of Stage IIIC or IV or Recurrent ALK-Positive Non-small Cell Lung Cancer

Active Not Recruiting
NCT06955325Phase 3

Umbrella Trial of Adjuvant Therapy in Completely Resected High-risk Stage IA-IB NSCLC: Focus on Driver Mutations

Not Yet Recruiting
NCT06785584Phase 4

Efficacy and Safety of Ensartinib in Neoadjuvant Therapy for Stage IIA - IIIB (Operable or Potentially Operable) ALK-Positive Lung Adenocarcinoma :A Multicenter, Real-World Clinical Study

Not Yet Recruiting
NCT06780839Phase 2

Adjuvant Treatment of ALK-positive Non-small Cell Lung Cancer with Ensartinib Guided by MRD

Not Yet Recruiting
NCT06779539Phase 2

Neoadjuvant Ensartinib in ALK Positive Resectable Stage II to III Non-Small Cell Lung Cancer

Not Yet Recruiting
NCT06762327Phase 2

Ensartinib in the Treatment of ALK Positive or MET Exon 14 Skipping Anvanced Solid Tumors Excluded Lung Cancer

Not Yet Recruiting
NCT05341583Phase 3

Ensartinib as Adjuvant Treatment in Anaplastic Lymphoma Kinase (ALK) Positive Non-small Cell Lung Cancer

Recruiting
NCT06492525Phase 1

A Study To Evaluate The Effect Of Rifampicin Or Ltraconazole On Pharmacokinetics Of Ensartinib In Healthy Volunteers

Not Yet Recruiting
NCT05241028Phase 2

Adjuvant Therapy of Ensartinib in Stage IB-IIIA ALK-positive Non-small Cell Lung Cancer

Recruiting
NCT02959619Phase 1

Ensartinib in Non-small Cell Lung Cancer Patients With Positive ALK

Completed
NCT04146571

Expanded Access to Ensartinib for Participants With ALK+ NSCLC

Unknown
NCT02898116Phase 1

Phase 1/2 Study of Ensartinib and Durvalumab, in ALK-rearranged Non-small Cell Lung Cancer

Completed
NCT05380024Phase 2

A Study of Ensartinib as Neoadjuvant Therapy for Patients With ALK Positive Resectable Non-Small Cell Lung Cancer

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
23