Success Metrics

Clinical Success Rate
70.0%

Based on 7 completed trials

Completion Rate
70%(7/10)
Active Trials
46(78%)
Results Posted
100%(7 trials)
Terminated
3(5%)

Phase Distribution

Ph phase_1
16
27%
Ph phase_2
33
56%
Ph phase_3
6
10%
Ph phase_4
2
3%

Phase Distribution

16

Early Stage

33

Mid Stage

8

Late Stage

Phase Distribution57 total trials
Phase 1Safety & dosage
16(28.1%)
Phase 2Efficacy & side effects
33(57.9%)
Phase 3Large-scale testing
6(10.5%)
Phase 4Post-market surveillance
2(3.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

70.0%

7 of 10 finished

Non-Completion Rate

30.0%

3 ended early

Currently Active

46

trials recruiting

Total Trials

59

all time

Status Distribution
Active(49)
Completed(7)
Terminated(3)

Detailed Status

Recruiting35
Active, not recruiting11
Completed7
Terminated3
Not yet recruiting3

Development Timeline

Analytics

Development Status

Total Trials
59
Active
46
Success Rate
70.0%
Most Advanced
Phase 4

Trials by Phase

Phase 116 (28.1%)
Phase 233 (57.9%)
Phase 36 (10.5%)
Phase 42 (3.5%)

Trials by Status

active_not_recruiting1119%
terminated35%
completed712%
not_yet_recruiting35%
recruiting3559%

Recent Activity

Clinical Trials (59)

Showing 20 of 59 trialsScroll for more
NCT04963153Phase 1

Testing Combination Erdafitinib and Enfortumab Vedotin in Metastatic Bladder Cancer After Treatment With Chemotherapy and Immunotherapy

Active Not Recruiting
NCT05756569Phase 2

Enfortumab Vedotin Plus Pembrolizumab for the Treatment of Locally Advanced or Metastatic Bladder Cancer of Variant Histology

Recruiting
NCT06809140Phase 2

Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer

Recruiting
NCT05868265Phase 2

A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract

Active Not Recruiting
NCT07720284Phase 3

An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC

Recruiting
NCT07421700Phase 1

Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

Recruiting
NCT02091999Phase 1

A Study of Escalating Doses of ASG-22CE Given as Monotherapy in Subjects With Metastatic Urothelial Cancer and Other Malignant Solid Tumors That Express Nectin-4

Completed
NCT06356155Phase 2

Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Upper Tract Urothelial Cancer

Recruiting
NCT05775471Phase 2

Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancer

Recruiting
NCT07475806Phase 2

A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder

Recruiting
NCT07139977Phase 2

Study of EV for Recurrent Endometrial Carcinoma

Recruiting
NCT06011954

A Study to Survey Adults in South Korea With Cancer Who Receive PADCEV Injection

Recruiting
NCT07566156Phase 3

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

Recruiting
NCT03924895Phase 3

Perioperative Pembrolizumab (MK-3475) Plus Cystectomy or Perioperative Pembrolizumab Plus Enfortumab Vedotin Plus Cystectomy Versus Cystectomy Alone in Participants Who Are Cisplatin-ineligible or Decline Cisplatin With Muscle-invasive Bladder Cancer (MK-3475-905/KEYNOTE-905/EV-303)

Active Not Recruiting
NCT07663747Phase 2

Enfortumab Vedotin + Pembrolizumab Induction to Spare the Bladder in MIBC

Not Yet Recruiting
NCT06041503Phase 2

Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE)

Recruiting
NCT07667335Phase 1

Enfortumab Vedotin, Pembrolizumab and Quemliclustat for the Treatment of Unresectable Locally Advanced and Metastatic Urothelial Cancer

Not Yet Recruiting
NCT07110038Phase 2

DEPECA-1 - A Phase II Study to Evaluate a First-line Systemic Therapy With Enfortumab Vedotin Plus Avelumab for Advanced and Metastatic Penile Carcinoma

Recruiting
NCT05614739Phase 1

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

Recruiting
NCT06311214Phase 2

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
59