Success Metrics

Clinical Success Rate
66.7%

Based on 4 completed trials

Completion Rate
67%(4/6)
Active Trials
6(38%)
Results Posted
150%(6 trials)
Terminated
2(13%)

Phase Distribution

Ph phase_1
1
6%
Ph phase_2
13
81%
Ph phase_3
2
13%

Phase Distribution

1

Early Stage

13

Mid Stage

2

Late Stage

Phase Distribution16 total trials
Phase 1Safety & dosage
1(6.3%)
Phase 2Efficacy & side effects
13(81.3%)
Phase 3Large-scale testing
2(12.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

66.7%

4 of 6 finished

Non-Completion Rate

33.3%

2 ended early

Currently Active

6

trials recruiting

Total Trials

16

all time

Status Distribution
Active(10)
Completed(4)
Terminated(2)

Detailed Status

Recruiting6
Not yet recruiting4
Completed4
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
16
Active
6
Success Rate
66.7%
Most Advanced
Phase 3

Trials by Phase

Phase 11 (6.3%)
Phase 213 (81.3%)
Phase 32 (12.5%)

Trials by Status

recruiting638%
not_yet_recruiting425%
terminated213%
completed425%

Recent Activity

Clinical Trials (16)

Showing 16 of 16 trials
NCT07202598Phase 2

Randomized Stepped Wedge Study of Emapalumab in APECED Enteritis

Recruiting
NCT06285825Phase 2

A Pilot Study of Emapalumab for the Treatment of CAR T-Cell Therapy-Associated Prolonged Cytopenia

Recruiting
NCT07744919Phase 2

Severe Hepatitis Intervention With Emapalumab for Liver Disease

Not Yet Recruiting
NCT06996119Phase 1

Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant

Recruiting
NCT07486869Phase 2

Emapalumab MDA5 Rapidly Progressive Interstitial Lung Disease (RP-ILD) Study

Not Yet Recruiting
NCT05787574Phase 2

A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition

Recruiting
NCT07567014Phase 2

Emapalumab Prophylaxis of Bispecific T-Cell Engagers (BiTEs) Associated CRS and ICANS

Not Yet Recruiting
NCT07538336Phase 2

Targeting Interferon Gamma With Emapalumab to Lung Transplant Recipients With Interferon Gamma-high Acute Lung Allograft Dysfunction

Not Yet Recruiting
NCT05001737Phase 3

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE

Completed
NCT06430788Phase 2

A Study of Emapalumab for Pediatric Aplastic Anemia

Recruiting
NCT06550141Phase 2

Emapalumab Prevention of CAR-T Cell Associated Toxicities

Recruiting
NCT03312751Phase 3

Study to Assess the Efficacy and Safety of Emapalumab in Primary Haemophagocytic Lymphohistiocytosis

Completed
NCT04731298Phase 2

Study to Investigate the Pharmacokinetics, Pharmacodynamics and Assess the Efficacy and Safety to Support Dose Selection of Emapalumab in Pre-empting Graft Failure in Patients at High Risk After HSCT.

Terminated
NCT02069899Phase 2

A Study for Long-term Follow-up of Hemophagocytic Lymphohistiocytosis (HLH) Participants Who Received Treatment With Emapalumab (NI-0501), an Anti-interferon Gamma Monoclonal Antibody

Completed
NCT03311854Phase 2

A Study to Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)

Completed
NCT04324021Phase 2

Efficacy and Safety of Emapalumab and Anakinra in Reducing Hyperinflammation and Respiratory Distress in Patients With COVID-19 Infection.

Terminated

All 16 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
16