Success Metrics

Clinical Success Rate
80.0%

Based on 8 completed trials

Completion Rate
80%(8/10)
Active Trials
1(8%)
Results Posted
88%(7 trials)
Terminated
2(15%)

Phase Distribution

Ph phase_4
1
8%
Ph phase_1
2
15%
Ph phase_2
6
46%
Ph phase_3
3
23%

Phase Distribution

2

Early Stage

6

Mid Stage

4

Late Stage

Phase Distribution12 total trials
Phase 1Safety & dosage
2(16.7%)
Phase 2Efficacy & side effects
6(50.0%)
Phase 3Large-scale testing
3(25.0%)
Phase 4Post-market surveillance
1(8.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.0%

8 of 10 finished

Non-Completion Rate

20.0%

2 ended early

Currently Active

1

trials recruiting

Total Trials

13

all time

Status Distribution
Active(2)
Completed(8)
Terminated(2)
Other(1)

Detailed Status

Completed8
Terminated2
Active, not recruiting1
unknown1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
13
Active
1
Success Rate
80.0%
Most Advanced
Phase 4

Trials by Phase

Phase 12 (16.7%)
Phase 26 (50.0%)
Phase 33 (25.0%)
Phase 41 (8.3%)

Trials by Status

active_not_recruiting18%
unknown18%
not_yet_recruiting18%
completed862%
terminated215%

Recent Activity

Clinical Trials (13)

Showing 13 of 13 trials
NCT07531251Phase 4

Clinical Trial in Patients With Barth Syndrome- 4TAZPower

Not Yet Recruiting
NCT05168774Phase 1

FRDA Investigator Initiated Study (IIS) With Elamipretide

Completed
NCT06373731Phase 3

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD)

Active Not Recruiting
NCT05162768Phase 3

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD)

Completed
NCT04689360

An Intermediate Size Expanded Access Protocol of Elamipretide

Unknown
NCT03098797Phase 2

A Trial to Evaluate Safety, Tolerability and Efficacy of Elamipretide in Subjects With Barth Syndrome

Completed
NCT03323749Phase 3

A Trial to Evaluate Safety and Efficacy of Elamipretide Primary Mitochondrial Myopathy Followed by Open-Label Extension

Terminated
NCT02976038Phase 2

Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)

Terminated
NCT02848313Phase 1

An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects With Intermediate Age-Related Macular Degeneration

Completed
NCT02914665Phase 2

A Phase 2 Study to Evaluate the Cardiac and Renal Effects of Short Term Treatment With Elamipretide in Patients Hospitalized With Congestion Due to Heart Failure

Completed
NCT02805790Phase 2

Safety, Tolerability, Efficacy of MTP-131 for Treatment of Mitochondrial Disease in Subjects From the MMPOWER Study

Completed
NCT02245620Phase 2

A Phase 2 Study to Evaluate the Impact of MTP-131 (Bendavia™) on Skeletal Muscle Function in Elderly

Completed
NCT02814097Phase 2

A Study to Evaluate the Effects of 4 Weeks Treatment With Subcutaneous Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Preserved Ejection Fraction

Completed

All 13 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
13