Success Metrics

Clinical Success Rate
60.0%

Based on 3 completed trials

Completion Rate
60%(3/5)
Active Trials
23(72%)
Results Posted
67%(2 trials)
Terminated
2(6%)

Phase Distribution

Ph phase_3
5
16%
Ph phase_1
12
38%
Ph phase_2
12
38%
Ph early_phase_1
1
3%

Phase Distribution

13

Early Stage

12

Mid Stage

5

Late Stage

Phase Distribution30 total trials
Early Phase 1First-in-human
1(3.3%)
Phase 1Safety & dosage
12(40.0%)
Phase 2Efficacy & side effects
12(40.0%)
Phase 3Large-scale testing
5(16.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

3 of 6 finished

Non-Completion Rate

50.0%

3 ended early

Currently Active

23

trials recruiting

Total Trials

32

all time

Status Distribution
Active(26)
Completed(3)
Terminated(3)

Detailed Status

Recruiting20
Active, not recruiting3
Completed3
Not yet recruiting3
Terminated2
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
32
Active
23
Success Rate
60.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (3.3%)
Phase 112 (40.0%)
Phase 212 (40.0%)
Phase 35 (16.7%)

Trials by Status

active_not_recruiting39%
recruiting2063%
terminated26%
completed39%
not_yet_recruiting39%
withdrawn13%

Recent Activity

Clinical Trials (32)

Showing 20 of 32 trialsScroll for more
NCT06120283Phase 1

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

Recruiting
NCT06075953Phase 2

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

Recruiting
NCT06923527Phase 2

Circulating Tumor DNA

Recruiting
NCT05512364Phase 3

Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA)

Recruiting
NCT06492616Phase 3

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Recruiting
NCT07766018Phase 2

A Phase 2 Bridging Study of Elacestrant Monotherapy in Advanced or Metastatic Breast Cancer

Recruiting
NCT05386108Phase 1

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Recruiting
NCT07222215Phase 2

PhII Randomized CAPecitabine + ELAcestrant vs. Capecitabine Alone in ER+ Breast Cancer (CAPELA)

Recruiting
NCT06382948Phase 3

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.

Recruiting
NCT06691035Phase 1

Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer

Active Not Recruiting
NCT07753954Phase 2

Medical Imaging to Re-evaluate Elacestrant Clinical Usage

Not Yet Recruiting
NCT07242352Phase 3

Marker - Adjusted Therapy Comparing Adjuvant Elacestrant With Standard Endocrine Treatment in Genomically and/or Clinically High-risk ER+/HER2- eBC

Recruiting
NCT06638307Phase 1

A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer

Recruiting
NCT05618613Phase 1

Study of Elacestrant in Combination With Onapristone in Patients With Advanced or Metastatic Breast Cancer

Terminated
NCT07209449Phase 2

A Study of Elacestrant Alone or in Combination With Abemaciclib in People With Endometrial Cancer

Recruiting
NCT07563595

Elacestrant in Patients With ER+ HER2- ESR1-mutated Locally Advanced or Metastatic Breast Cancer

Recruiting
NCT05573126Phase 1

Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

Recruiting
NCT05563220Phase 1

Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer

Active Not Recruiting
NCT07198724Phase 1

ERADICATE: A Phase Ib/II Study of Elacestrant Plus Trastuzumab Deruxtecan in Patients With CDK4/6 Inhibitor and Endocrine-resistant HR+/HER2-low or HER2-ultralow Metastatic Breast Cancer

Recruiting
NCT07634601Phase 2

Elacestrant With Everolimus for the Treatment of Recurrent Advanced or Metastatic ER-Positive Endometrial Cancer

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
32