Success Metrics

Clinical Success Rate
60.0%

Based on 3 completed trials

Completion Rate
60%(3/5)
Active Trials
22(73%)
Results Posted
67%(2 trials)
Terminated
2(7%)

Phase Distribution

Ph phase_3
5
17%
Ph phase_1
12
40%
Ph phase_2
10
33%
Ph early_phase_1
1
3%

Phase Distribution

13

Early Stage

10

Mid Stage

5

Late Stage

Phase Distribution28 total trials
Early Phase 1First-in-human
1(3.6%)
Phase 1Safety & dosage
12(42.9%)
Phase 2Efficacy & side effects
10(35.7%)
Phase 3Large-scale testing
5(17.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

3 of 6 finished

Non-Completion Rate

50.0%

3 ended early

Currently Active

22

trials recruiting

Total Trials

30

all time

Status Distribution
Active(24)
Completed(3)
Terminated(3)

Detailed Status

Recruiting20
Completed3
Not yet recruiting2
Terminated2
Active, not recruiting2
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
30
Active
22
Success Rate
60.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (3.6%)
Phase 112 (42.9%)
Phase 210 (35.7%)
Phase 35 (17.9%)

Trials by Status

not_yet_recruiting27%
recruiting2067%
terminated27%
withdrawn13%
completed310%
active_not_recruiting27%

Recent Activity

Clinical Trials (30)

Showing 20 of 30 trialsScroll for more
NCT06120283Phase 1

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

Recruiting
NCT05386108Phase 1

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Recruiting
NCT05618613Phase 1

Study of Elacestrant in Combination With Onapristone in Patients With Advanced or Metastatic Breast Cancer

Terminated
NCT06075953Phase 2

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

Recruiting
NCT06638307Phase 1

A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer

Recruiting
NCT07209449Phase 2

A Study of Elacestrant Alone or in Combination With Abemaciclib in People With Endometrial Cancer

Recruiting
NCT06492616Phase 3

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Recruiting
NCT06923527Phase 2

Circulating Tumor DNA

Recruiting
NCT07563595

Elacestrant in Patients With ER+ HER2- ESR1-mutated Locally Advanced or Metastatic Breast Cancer

Recruiting
NCT05573126Phase 1

Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

Recruiting
NCT05563220Phase 1

Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer

Active Not Recruiting
NCT07222215Phase 2

PhII Randomized CAPecitabine + ELAcestrant vs. Capecitabine Alone in ER+ Breast Cancer (CAPELA)

Recruiting
NCT07198724Phase 1

ERADICATE: A Phase Ib/II Study of Elacestrant Plus Trastuzumab Deruxtecan in Patients With CDK4/6 Inhibitor and Endocrine-resistant HR+/HER2-low or HER2-ultralow Metastatic Breast Cancer

Recruiting
NCT07634601Phase 2

Elacestrant With Everolimus for the Treatment of Recurrent Advanced or Metastatic ER-Positive Endometrial Cancer

Not Yet Recruiting
NCT07612215Phase 1

Elacestrant in Advanced Triple Positive Breast Cancer

Recruiting
NCT07467772Phase 2

Ph 2 Elacestrant in ER Positive Uterine Sarcomas

Recruiting
NCT05512364Phase 3

Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA)

Recruiting
NCT05596409Phase 2

ELACESTRANT in Women and Men With CDK4/6 Inhibitor-Naive Estrogen Receptor Positive, HER-2 Negative Metastatic Breast Cancer Study

Active Not Recruiting
NCT07242352Phase 3

Marker - Adjusted Therapy Comparing Adjuvant Elacestrant With Standard Endocrine Treatment in Genomically and/or Clinically High-risk ER+/HER2- eBC

Recruiting
NCT05982093Phase 2

Elacestrant With/Without Triptorelin in Premenopausal Women With Luminal Breast Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
30