Success Metrics

Clinical Success Rate
60.0%

Based on 3 completed trials

Completion Rate
60%(3/5)
Active Trials
20(71%)
Results Posted
33%(1 trials)
Terminated
2(7%)

Phase Distribution

Ph early_phase_1
1
4%
Ph phase_1
11
39%
Ph phase_2
9
32%
Ph phase_3
5
18%

Phase Distribution

12

Early Stage

9

Mid Stage

5

Late Stage

Phase Distribution26 total trials
Early Phase 1First-in-human
1(3.8%)
Phase 1Safety & dosage
11(42.3%)
Phase 2Efficacy & side effects
9(34.6%)
Phase 3Large-scale testing
5(19.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

3 of 6 finished

Non-Completion Rate

50.0%

3 ended early

Currently Active

20

trials recruiting

Total Trials

28

all time

Status Distribution
Active(22)
Completed(3)
Terminated(3)

Detailed Status

Recruiting19
Completed3
Terminated2
Not yet recruiting2
Active, not recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
28
Active
20
Success Rate
60.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (3.8%)
Phase 111 (42.3%)
Phase 29 (34.6%)
Phase 35 (19.2%)

Trials by Status

terminated27%
active_not_recruiting14%
withdrawn14%
recruiting1968%
completed311%
not_yet_recruiting27%

Recent Activity

Clinical Trials (28)

Showing 20 of 28 trialsScroll for more
NCT07242352Phase 3

Marker - Adjusted Therapy Comparing Adjuvant Elacestrant With Standard Endocrine Treatment in Genomically and/or Clinically High-risk ER+/HER2- eBC

Recruiting
NCT06075953Phase 2

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

Recruiting
NCT07563595

Elacestrant in Patients With ER+ HER2- ESR1-mutated Locally Advanced or Metastatic Breast Cancer

Not Yet Recruiting
NCT06923527Phase 2

Circulating Tumor DNA

Recruiting
NCT05982093Phase 2

Elacestrant With/Without Triptorelin in Premenopausal Women With Luminal Breast Cancer

Recruiting
NCT06492616Phase 3

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Recruiting
NCT05596409Phase 2

ELACESTRANT in Women and Men With CDK4/6 Inhibitor-Naive Estrogen Receptor Positive, HER-2 Negative Metastatic Breast Cancer Study

Active Not Recruiting
NCT07467772Phase 2

Ph 2 Elacestrant in ER Positive Uterine Sarcomas

Recruiting
NCT06120283Phase 1

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

Recruiting
NCT06638307Phase 1

A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer

Recruiting
NCT07198724Phase 1

ERADICATE: A Phase Ib/II Study of Elacestrant Plus Trastuzumab Deruxtecan in Patients With CDK4/6 Inhibitor and Endocrine-resistant HR+/HER2-low or HER2-ultralow Metastatic Breast Cancer

Recruiting
NCT04791384Phase 1

Phase Ib/II Trial of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/Her2- Breast Cancer

Terminated
NCT05573126Phase 1

Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

Recruiting
NCT07209449Phase 2

A Study of Elacestrant Alone or in Combination With Abemaciclib in People With Endometrial Cancer

Recruiting
NCT06382948Phase 3

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.

Recruiting
NCT05386108Phase 1

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Recruiting
NCT07222215Phase 2

PhII Randomized CAPecitabine + ELAcestrant vs. Capecitabine Alone in ER+ Breast Cancer (CAPELA)

Recruiting
NCT05563220Phase 1

Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer

Recruiting
NCT06691035Phase 1

Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer

Recruiting
NCT07159451Phase 2

A Short-term Preoperative, Evaluating Activity and Safety of Elacestrant Monotherapy as Compared to Elacestrant + Ovarian Function Suppression (LHRH Agonist) in Premenopausal Patients With Stage I-II ER+/HER2- Breast Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
28