Registry-listed formulations

efalizumab · mesh:C472181

Each study is counted once in the molecule profile. Registry products remain separate. Naming an ingredient does not establish that products are interchangeable or what participants received.

12 source entries across 12 studies. This list may not include all unresolved or historical entries.

  • Raptiva (efalizumab)Registry intervention

    Linked study entry; product equivalence not established

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  • Raptiva (efalizumab)Registry intervention

    Linked study entry; product equivalence not established

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  • Raptiva (efalizumab)Registry intervention

    Linked study entry; product equivalence not established

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  • Raptiva (efalizumab)Registry intervention

    Linked study entry; product equivalence not established

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  • Efalizumab treatmentRegistry intervention

    Linked study entry; product equivalence not established

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  • RaptivaRegistry intervention

    Linked study entry; product equivalence not established

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  • RaptivaRegistry intervention

    Linked study entry; product equivalence not established

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  • RaptivaRegistry intervention

    Linked study entry; product equivalence not established

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  • RaptivaRegistry intervention

    Linked study entry; product equivalence not established

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  • Raptiva (efalizumab)Registry intervention

    Linked study entry; product equivalence not established

    View study and source
  • RaptivaRegistry intervention

    Linked study entry; product equivalence not established

    View study and source
  • Efalizumab (Raptiva)Registry intervention

    Linked study entry; product equivalence not established

    View study and source

Success Metrics

Clinical Success Rate
82.4%

Based on 22 completed trials

Completion Rate
79%(22/28)
Active Trials
0(0%)
Results Posted
55%(12 trials)
Terminated
6(18%)

Phase Distribution

Phase 4
7
21%
Phase 2
7
21%
Phase 1/2
4
12%
Phase 2/3
1
3%
Phase 3
6
18%
Phase 1
6
18%
Not Applicable
2
6%

Phase Distribution

6

Early Stage

12

Mid Stage

13

Late Stage

Phase Distribution33 total trials
Phase 1Safety & dosage
6(18.2%)
Phase 1/2Combined phases
4(12.1%)
Phase 2Efficacy & side effects
7(21.2%)
Phase 2/3Combined phases
1(3.0%)
Phase 3Large-scale testing
6(18.2%)
Phase 4Post-market surveillance
7(21.2%)
N/ANon-phased studies
2(6.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

64.7%

22 of 34 finished

Non-Completion Rate

35.3%

12 ended early

Currently Active

0

trials recruiting

Total Trials

34

all time

Status Distribution
Completed(22)
Terminated(12)

Detailed Status

Completed22
Terminated6
Withdrawn6

Development Timeline

Analytics

Development Status

Total Trials
34
Active
0
Success Rate
82.4%
Most Advanced
Phase 4

Trials by Phase

Phase 16 (18.2%)
Phase 1/24 (12.1%)
Phase 27 (21.2%)
Phase 2/31 (3.0%)
Phase 36 (18.2%)
Phase 47 (21.2%)
N/A2 (6.1%)

Trials by Status

completed2265%
terminated618%
withdrawn618%

Recent Activity

Clinical Trials (34)

Showing 20 of 34 trialsScroll for more
NCT00115076Phase 3

Study of the Drug Efalizumab (Raptiva), for Adult Patients With Moderate to Severe Plaque Psoriasis

Completed
NCT00308204Phase 2

Discoid Lupus Erythematosus of the Scalp and a Trial of Biologic Therapy With Raptiva

Withdrawn
NCT00226057Phase 1

Efalizumab for Moderate to Severe Atopic Dermatitis

Completed
NCT00368654Phase 1/2

Evaluate Whether Combination Therapy With Methotrexate and Raptiva in Psoriasis Patients is Safe and Increases Efficacy

Completed
NCT00287118Phase 4

A Multicentre, Open Label Phase IIIb/IV Study of Subcutaneously Administered Raptiva in the Treatment of Adult Subjects With Moderate to Severe Plaque Psoriasis

Completed
NCT00672204Phase 1/2

Raptiva and Sirolimus in Islet Transplantation for Type 1 Diabetes

Terminated
NCT00729768Phase 2/3

A Study to Evaluate Efalizumab Compared With Cyclosporine As an Immunosuppressant Regimen in De Novo Renal Transplantation

Withdrawn
NCT00669214Phase 4

A Study to Evaluate the Safety and Efficacy of Efalizumab in Adult Patients With Moderate to Severe Plaque Psoriasis With Involvement of the Scalp

Completed
NCT00489216Not Applicable

Efalizumab in Treating Patients With Graft-Versus-Host Disease of the Skin That Did Not Respond to Previous Steroids

Terminated
NCT00312026Phase 4

A Study to Evaluate the Safety and Efficacy of Efalizumab in Adult Patients With Plaque Psoriasis Involving the Hands and/or Feet

Completed
NCT00442650Phase 3

Efalizumab for Treatment of Patients With Moderate to Severe Psoriasis

Completed
NCT00676559Phase 1

Combined aPproach to Treatment Using Ranibizumab and Efalizumab for Diabetic Macular Edema Study: The CAPTURE DME Study

Withdrawn
NCT00276250Phase 2

Islet Transplantation Using Abatacept

Completed
NCT00746980Phase 2

Efalizumab in the Treatment of Alopecia, Phase II

Withdrawn
NCT00344448Phase 2

Pilot Study of Raptiva to Treat Sjogren's Syndrome

Terminated
NCT00336973Phase 4

A Study to Evaluate Raptiva in Subjects With Chronic Moderate or Worse Plaque Psoriasis Who Have Had an Inadequate Response to an Anti-TNF Agent

Completed
NCT00737763Phase 2

Beta Cell Rescue in New Onset Type 1 Diabetes With Efalizumab

Withdrawn
NCT00096603Phase 3

A Study to Evaluate the Safety of Raptiva in Adults With Plaque Psoriasis Previously Enrolled in Study ACD2600g

Completed
NCT00338143Phase 3

A Study to Evaluate Efalizumab in Adults With Plaque Psoriasis, Including Those Who Are Receiving Concomitant Antipsoriatic Therapies

Completed
NCT00972543Phase 4

Raptiva in Palm and Sole Psoriasis

Terminated

Drug Details

Intervention Type
Varies by study
Molecule Type
Antibody
Total Trials
34

External References

Names & Codes

Trade Names

Raptiva

ATC Classification

Research Codes

ANTI-CD11AHU-1124