Success Metrics

Clinical Success Rate
83.1%

Based on 98 completed trials

Completion Rate
83%(98/118)
Active Trials
6(4%)
Results Posted
46%(45 trials)
Terminated
20(13%)

Phase Distribution

Ph phase_1
35
23%
Ph phase_2
41
27%
Ph early_phase_1
5
3%
Ph phase_3
15
10%
Ph not_applicable
18
12%
Ph phase_4
35
23%

Phase Distribution

40

Early Stage

41

Mid Stage

50

Late Stage

Phase Distribution149 total trials
Early Phase 1First-in-human
5(3.4%)
Phase 1Safety & dosage
35(23.5%)
Phase 2Efficacy & side effects
41(27.5%)
Phase 3Large-scale testing
15(10.1%)
Phase 4Post-market surveillance
35(23.5%)
N/ANon-phased studies
18(12.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

79.7%

98 of 123 finished

Non-Completion Rate

20.3%

25 ended early

Currently Active

6

trials recruiting

Total Trials

153

all time

Status Distribution
Active(7)
Completed(98)
Terminated(25)
Other(23)

Detailed Status

Completed98
unknown23
Terminated20
Recruiting5
Withdrawn5
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
153
Active
6
Success Rate
83.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 15 (3.4%)
Phase 135 (23.5%)
Phase 241 (27.5%)
Phase 315 (10.1%)
Phase 435 (23.5%)
N/A18 (12.1%)

Trials by Status

active_not_recruiting11%
terminated2013%
recruiting53%
not_yet_recruiting11%
completed9864%
withdrawn53%
unknown2315%

Recent Activity

Clinical Trials (153)

Showing 20 of 153 trialsScroll for more
NCT05592678Not Applicable

δ in Dementia Clinical Trials

Recruiting
NCT04661280Phase 3

Donepezil Versus Non-drug Treatment in Alzheimer's Disease.

Recruiting
NCT03810794Not Applicable

Clinical Evaluation on the Therapeutic Effect of Acupuncture Treatment for Alzheimer's Disease

Recruiting
NCT06285240Phase 1

Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia Taking Stable Donepezil Treatment (MK-1167-007)

Completed
NCT05438264Early Phase 1

Effect of Donepezil on Speech Recognition in Cochlear Implant Users

Active Not Recruiting
NCT06041789Phase 2

Effect of Acetylcholinesterase Inhibitors on Bone Metabolism

Recruiting
NCT06518941Phase 2

An Open Trial of a Novel Pharmacotherapy for Habit Modification in Anorexia Nervosa

Not Yet Recruiting
NCT06417086Not Applicable

Clinical Evaluation of Acupuncture Treatment on Alzheimer's Disease in APOE e4 Carriers and Non-Carriers

Recruiting
NCT04117178Phase 4

Monitoring Anti-Dementia Drugs by Serum Levels

Completed
NCT02255799Phase 3

Multicenter Evaluation of Memory Remediation After TBI With Donepezil

Completed
NCT04730635Phase 1

Cognition Platform Study in Participants at Risk for Alzheimer's Disease (AD) (MK-0000-413)

Completed
NCT02787746Phase 4

Safety and Efficacy of Donepezil in Mild to Moderate Alzheimer's Disease

Completed
NCT02635750Phase 1

Investigation of Pharmacokinetic Drug-drug Interaction of BI 409306 and Donepezil in Healthy Male and Female Subjects

Completed
NCT04308304Phase 1

MK-1942/Donepezil Interactions in Participants With Alzheimer's Disease (MK-1942-005)

Completed
NCT01442766Phase 1

Donepezil Trial for Motor Recovery in Acute Stroke

Withdrawn
NCT05254639Phase 2

Donepezil for Oxaliplatin-induced Neuropathy Peripheral Neuropathy: Proof of Concept Study

Completed
NCT02580305Phase 2

SUVN-502 With Donepezil and Memantine for the Treatment of Moderate Alzheimer's Disease- Phase 2a Study

Completed
NCT04505670Phase 2

The Effect of Donepezil on Wound Healing

Unknown
NCT05811000Phase 2

A Phase 2 Clinical Study to Explore the Optimal Dosage/Administration of PM012 Tablet in Alzheimer's Disease

Unknown
NCT05540977Early Phase 1

Donepezil Prevents Urinary Retention After Extensive Total Hysterectomy

Unknown

Drug Details

Intervention Type
OTHER
Total Trials
153