Success Metrics

Clinical Success Rate
88.9%

Based on 8 completed trials

Completion Rate
89%(8/9)
Active Trials
9(45%)
Results Posted
150%(12 trials)
Terminated
1(5%)

Phase Distribution

Ph phase_3
4
20%
Ph phase_2
8
40%
Ph phase_1
7
35%

Phase Distribution

7

Early Stage

8

Mid Stage

4

Late Stage

Phase Distribution19 total trials
Phase 1Safety & dosage
7(36.8%)
Phase 2Efficacy & side effects
8(42.1%)
Phase 3Large-scale testing
4(21.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

88.9%

8 of 9 finished

Non-Completion Rate

11.1%

1 ended early

Currently Active

9

trials recruiting

Total Trials

20

all time

Status Distribution
Active(11)
Completed(8)
Terminated(1)

Detailed Status

Completed8
Active, not recruiting5
Recruiting4
Not yet recruiting2
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
20
Active
9
Success Rate
88.9%
Most Advanced
Phase 3

Trials by Phase

Phase 17 (36.8%)
Phase 28 (42.1%)
Phase 34 (21.1%)

Trials by Status

terminated15%
completed840%
not_yet_recruiting210%
active_not_recruiting525%
recruiting420%

Recent Activity

Clinical Trials (20)

Showing 20 of 20 trials
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT07437963Phase 1

Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten Worse

Not Yet Recruiting
NCT01711554Phase 1

Lenalidomide and Dinutuximab With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent Neuroblastoma

Active Not Recruiting
NCT03786783Phase 2

Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Active Not Recruiting
NCT02573896Phase 1

Immunotherapy of Relapsed Refractory Neuroblastoma With Expanded NK Cells

Active Not Recruiting
NCT06450041Phase 2

NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

Recruiting
NCT00026312Phase 3

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma

Completed
NCT04238819Phase 1

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Completed
NCT03126916Phase 3

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Recruiting
NCT03794349Phase 2

Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma

Active Not Recruiting
NCT04751383Phase 1

Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma

Completed
NCT07261241Phase 2

NANT 2021-02: Randomized MIBG With Vorinostat/Dinutuximab/Vorinostat + Dinutuximab

Not Yet Recruiting
NCT04385277Phase 2

Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL)

Active Not Recruiting
NCT04211675Phase 1

NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab

Recruiting
NCT03332667Phase 1

MIBG With Dinutuximab +/- Vorinostat

Completed
NCT02484443Phase 2

Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma

Completed
NCT01767194Phase 2

Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma

Completed
NCT01041638Phase 3

Monoclonal Antibody Ch14.18, Sargramostim, Aldesleukin, and Isotretinoin After Autologous Stem Cell Transplant in Treating Patients With Neuroblastoma

Completed
NCT03098030Phase 2

Dinutuximab and Irinotecan Versus Irinotecan to Treat Subjects With Relapsed or Refractory Small Cell Lung Cancer

Completed
NCT02693171

Post-Marketing Assessment of Immunogenicity and Safety of Unituxin® in High-Risk Neuroblastoma Patients

Terminated

All 20 trials loaded

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
20