Success Metrics

Clinical Success Rate
88.6%

Based on 31 completed trials

Completion Rate
89%(31/35)
Active Trials
3(7%)
Results Posted
29%(9 trials)
Terminated
4(9%)

Phase Distribution

Ph early_phase_1
1
2%
Ph phase_4
13
28%
Ph phase_2
5
11%
Ph phase_3
4
9%
Ph not_applicable
2
4%
Ph phase_1
21
46%

Phase Distribution

22

Early Stage

5

Mid Stage

17

Late Stage

Phase Distribution46 total trials
Early Phase 1First-in-human
1(2.2%)
Phase 1Safety & dosage
21(45.7%)
Phase 2Efficacy & side effects
5(10.9%)
Phase 3Large-scale testing
4(8.7%)
Phase 4Post-market surveillance
13(28.3%)
N/ANon-phased studies
2(4.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

86.1%

31 of 36 finished

Non-Completion Rate

13.9%

5 ended early

Currently Active

3

trials recruiting

Total Trials

46

all time

Status Distribution
Active(4)
Completed(31)
Terminated(5)
Other(6)

Detailed Status

Completed31
unknown6
Terminated4
Recruiting2
Active, not recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
46
Active
3
Success Rate
88.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (2.2%)
Phase 121 (45.7%)
Phase 25 (10.9%)
Phase 34 (8.7%)
Phase 413 (28.3%)
N/A2 (4.3%)

Trials by Status

unknown613%
terminated49%
completed3167%
recruiting24%
active_not_recruiting12%
withdrawn12%
not_yet_recruiting12%

Recent Activity

Clinical Trials (46)

Showing 20 of 46 trialsScroll for more
NCT07232589Phase 1

A Study of the Effect of Diltiazem on the Plasma Levels of Nemtabrutinib (MK-1026-022)

Active Not Recruiting
NCT07103655Phase 4

The Therapeutic Value of Mavacamten in Hypertrophic Cardiomyopathy With Mid-to-Apical Left Ventricular Obstruction

Not Yet Recruiting
NCT06534671Phase 4

Diltiazem in Jervell and Lange-Nielsen Syndrome

Completed
NCT06993038Phase 4

Adenosine vs Diltiazem for Treatment of SVT in the ED

Recruiting
NCT06818968Phase 1

A Study of the Effect of Multiple Doses of Diltiazem on the Plasma Levels of MK-6916 in Healthy Participants (MK-6916-005)

Completed
NCT04130438Phase 2

Efficacy of Medical Therapy in Women and Men With Angina and Myocardial Bridging

Terminated
NCT04153032Phase 2

Comparative Evaluation of MEBO Ointment and Topical Diltiazem Ointment in the Treatment of Acute Anal Fissure

Recruiting
NCT06703463Phase 1

A Drug-Drug Interaction Study of Diltiazem and MK-1167 in Healthy Adult Participants (MK-1167-006)

Completed
NCT06692647Phase 1

A Clinical Study of MK-4318 and Diltiazem in Healthy People (MK-4318-003)

Completed
NCT06662396Phase 1

A Study of Diltiazem With a Single Dose of MK-6552 in Healthy Adult Participants (MK-6552-007)

Completed
NCT04551963Phase 1

Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies

Completed
NCT03212716Phase 2

Efficiency of Antagonist Drugs of the Cellular Transcriptomic Signature of Influenza A Virus Infection.

Terminated
NCT05162222Phase 1

A Study to Evaluate the Effect of Co-administration of Itraconazole or Diltiazem on the Single-dose of Danicamtiv in Healthy Participants

Completed
NCT05261464Phase 4

Heart Rate Controller in Computed Tomography Coronary Angiography

Unknown
NCT05294887Phase 4

Randomized Trial to Examine a Differential Therapeutic Response in Symptomatic Patients With Non-obstructive Coronary Artery Disease

Unknown
NCT02695992Phase 4

Rate Control in Atrial Fibrillation II

Completed
NCT04154800Phase 1

A Study to Evaluate the Safety, Tolerability, Drug Levels and Drug Effects of Single and Multiple Doses of BMS-986209 in Healthy Participants

Completed
NCT04790331Early Phase 1

Efficacy of Oral Verapamil and Oral Diltiazim on Reduction of Intraoperative Bleeding During Endoscopic Sinus Surgery Under General Anesthesia

Unknown
NCT02300259Phase 1

A Study of LY2623091 in Healthy Participants

Completed
NCT03930433Phase 4

The Effect of Nebivolol in Hypertensive Patients With Coronary Arterial Spasm

Completed

Drug Details

Intervention Type
DRUG
Total Trials
46