Success Metrics

Clinical Success Rate
61.1%

Based on 11 completed trials

Completion Rate
61%(11/18)
Active Trials
9(32%)
Results Posted
82%(9 trials)
Terminated
7(25%)

Phase Distribution

Ph phase_3
6
21%
Ph phase_2
12
43%
Ph not_applicable
1
4%
Ph phase_1
9
32%

Phase Distribution

9

Early Stage

12

Mid Stage

6

Late Stage

Phase Distribution28 total trials
Phase 1Safety & dosage
9(32.1%)
Phase 2Efficacy & side effects
12(42.9%)
Phase 3Large-scale testing
6(21.4%)
N/ANon-phased studies
1(3.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

61.1%

11 of 18 finished

Non-Completion Rate

38.9%

7 ended early

Currently Active

9

trials recruiting

Total Trials

28

all time

Status Distribution
Active(9)
Completed(11)
Terminated(7)
Other(1)

Detailed Status

Completed11
Terminated7
Recruiting5
Active, not recruiting4
unknown1

Development Timeline

Analytics

Development Status

Total Trials
28
Active
9
Success Rate
61.1%
Most Advanced
Phase 3

Trials by Phase

Phase 19 (32.1%)
Phase 212 (42.9%)
Phase 36 (21.4%)
N/A1 (3.6%)

Trials by Status

active_not_recruiting414%
terminated725%
recruiting518%
completed1139%
unknown14%

Recent Activity

Clinical Trials (28)

Showing 20 of 28 trialsScroll for more
NCT07654426Phase 2

The CARDIOPROTECT Trial

Recruiting
NCT03020030Phase 3

Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents

Active Not Recruiting
NCT00980460Phase 3

Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer

Completed
NCT01871766Phase 2

Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

Active Not Recruiting
NCT03786783Phase 2

Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Completed
NCT07502521Phase 2

Dexrazoxane to Protect Against Hemorrhagic STEMI

Completed
NCT06647953Phase 3

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

Recruiting
NCT03164057Phase 2

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

Active Not Recruiting
NCT01864109Phase 2

Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing Sarcoma

Active Not Recruiting
NCT05292664Phase 1

Venetoclax Basket Trial for High Risk Hematologic Malignancies

Recruiting
NCT01231906Phase 3

Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma

Completed
NCT06220032Phase 3

Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma

Recruiting
NCT06262438Phase 2

CHIP-AML22/Quizartinib: Quizartinib + Chemotherapy in Newly Diagnosed Pediatric FLT3-ITD+ and NPM1wt AML Patients

Recruiting
NCT05858710Phase 1

Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue Sarcoma

Completed
NCT03930680Phase 1

Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane

Completed
NCT01523977Phase 1

Everolimus With Multiagent Re-Induction Chemotherapy in Pediatric Patients With ALL

Completed
NCT02584309Phase 2

Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma

Completed
NCT04997291Phase 1

Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery

Unknown
NCT03698227Phase 2

OlaReDo - Olaratumab and Rechallenge With Doxorubicin in Soft Tissue Sarcoma Patients

Terminated
NCT00038142Phase 2

Vincristine, Doxorubicin, Cyclophosphamide and Dexrazoxane (VACdxr) in High Risk Ewing's Sarcoma Patients

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
28