Success Metrics

Clinical Success Rate
87.9%

Based on 102 completed trials

Completion Rate
88%(102/116)
Active Trials
22(14%)
Results Posted
75%(76 trials)
Terminated
14(9%)

Phase Distribution

Ph phase_1
18
11%
Ph phase_4
32
20%
Ph phase_2
49
30%
Ph phase_3
41
25%
Ph not_applicable
8
5%
Ph early_phase_1
4
2%

Phase Distribution

22

Early Stage

49

Mid Stage

73

Late Stage

Phase Distribution152 total trials
Early Phase 1First-in-human
4(2.6%)
Phase 1Safety & dosage
18(11.8%)
Phase 2Efficacy & side effects
49(32.2%)
Phase 3Large-scale testing
41(27.0%)
Phase 4Post-market surveillance
32(21.1%)
N/ANon-phased studies
8(5.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

85.0%

102 of 120 finished

Non-Completion Rate

15.0%

18 ended early

Currently Active

22

trials recruiting

Total Trials

162

all time

Status Distribution
Active(26)
Completed(102)
Terminated(18)
Other(16)

Detailed Status

Completed102
unknown15
Terminated14
Recruiting11
Active, not recruiting11
Withdrawn4

Development Timeline

Analytics

Development Status

Total Trials
162
Active
22
Success Rate
87.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (2.6%)
Phase 118 (11.8%)
Phase 249 (32.2%)
Phase 341 (27.0%)
Phase 432 (21.1%)
N/A8 (5.3%)

Trials by Status

suspended11%
withdrawn42%
recruiting117%
terminated149%
active_not_recruiting117%
completed10263%
not_yet_recruiting42%
unknown159%

Recent Activity

Clinical Trials (162)

Showing 20 of 162 trialsScroll for more
NCT06472050Phase 4

Romosozumab Versus Denosumab in Glucocorticoid-induced Osteoporosis: an Extended Observation of a Randomized Controlled Trial at 48 Months

Completed
NCT03921060Phase 4

Markers of Osteoporosis in Cystic Fibrosis

Recruiting
NCT07546552Not Applicable

Clinical Relevance of Modifying RANKL Signaling During Folliculogenesis

Recruiting
NCT06374459Phase 1

Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis

Recruiting
NCT04232657Phase 2

Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI

Active Not Recruiting
NCT07537972Phase 2

Denosumab Strategy for Liver Cancer With Bone Metastases

Not Yet Recruiting
NCT05010590Phase 4

Anabolic Therapy in Postmenopausal Osteoporosis

Active Not Recruiting
NCT04067726Phase 2

RANKL Inhibition and Mammographic Breast Density

Active Not Recruiting
NCT03401060Phase 3

Interest of Denosumab Treatment in Osteoporosis Associated to Systemic Mastocytosis

Completed
NCT03620019Phase 2

Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma

Completed
NCT03839459Phase 2

Denosumab for Smoldering Multiple Myeloma

Completed
NCT05419050Phase 2

Study of Denosumab for Prevention of Skeletal Disease Progression in Children With Fibrous Dysplasia

Completed
NCT05866029Not Applicable

Study of the Key Techniques of Prevention and Treatment of Osteoporotic Refracture

Recruiting
NCT05666310Phase 4

Muscle Impact of Treating Osteoporosis

Active Not Recruiting
NCT06300229Phase 1

NAPO - Novel Approach for Oligospermia

Completed
NCT07283887Phase 4

Romosozumab and Denosumab, Alone or Combined, in Postmenopausal Osteoporosis

Recruiting
NCT07271771Phase 4

The Effect of Denosumab on Muscle and Strength and Insulin Sensitivity

Recruiting
NCT05884372Phase 4

Efficacy and Safety of Combination Denosumab With Eldecalcitol for Postmenopausal Women With Osteoporosis.(ESCORT)

Completed
NCT04087096Phase 4

Denosumab to Prevent High-Turnover Bone Loss After Bariatric Surgery

Completed
NCT05101018Phase 4

Treatment With Romosozumab Versus Denosumab to Improve Bone Mineral Density and Architecture in Subacute SCI

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
162